Effect of organic co-solvents in the evaluation of the hydroxyl radical scavenging activity by the 2-deoxyribose degradation assay: The paradigmatic case of α-lipoic acid

Autor: Andrea Brizzolari, Mario C. Foti, Luciano Saso, Nima Razzaghi-Asl, Giuseppe Matteo Campisi, Enzo Santaniello

Publikováno v: Biophysical chemistry
220 (2017): 1–6. doi:10.1016/j.bpc.2016.10.005
info:cnr-pdr/source/autori:Andrea Brizzolari, Giuseppe M. Campisi, Enzo Santaniello, Nima Razzaghi-Asl, Luciano Saso, Mario C. Foti/titolo:Effect of organic co-solvents in the evaluation of the hydroxyl radical scavenging activity by the 2-deoxyribose degradation assay: The paradigmatic case of ?-lipoic acid/doi:10.1016%2Fj.bpc.2016.10.005/rivista:Biophysical chemistry (Print)/anno:2017/pagina_da:1/pagina_a:6/intervallo_pagine:1–6/volume:220

The 2-deoxyribose degradation assay (2-DR assay) is an in vitro method broadly used for evaluating the scavenging activity against the hydroxyl radical (HO ). One of the major drawbacks of the assay, however, is that only water soluble compounds can

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https://pubmed.ncbi.nlm.nih.gov/27825024

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