Anti-EFG1 2′-OMethylRNA oligomer inhibits Candida albicans filamentation and attenuates the candidiasis in Galleria mellonella

Autor: Mariana Henriques, Dalila Mil-Homens, Daniela Araújo, Sónia Silva

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 27, Iss, Pp 517-523 (2022)
Molecular Therapy. Nucleic Acids
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

EFG1 is a central transcriptional regulator of filamentation that is an important virulence factor of Candida albicans. This study serves to assess in vivo the applicability of the anti-EFG1 2-OMethylRNA oligomer for inhibiting Candida albicans filam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8ec732ce2e08545126fdcdd6cd483e
http://www.sciencedirect.com/science/article/pii/S2162253121003218

Anti- EFG1 2'- O MethylRNA oligomer inhibits Candida albicans filamentation and attenuates the candidiasis in Galleria mellonella .

Autor: Araújo D; LIBRO - Laboratório de Investigação em Biofilmes Rosário Oliveira, CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal., Mil-Homens D; iBB-Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Lisbon University, 1049-001 Lisbon, Portugal., Henriques M; LIBRO - Laboratório de Investigação em Biofilmes Rosário Oliveira, CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal., Silva S; LIBRO - Laboratório de Investigação em Biofilmes Rosário Oliveira, CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal.; National Institute for Agrarian and Veterinary Research, Vairão, 4485-655 Vila do Conde, Portugal.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2021 Dec 16; Vol. 27, pp. 517-523. Date of Electronic Publication: 2021 Dec 16 (Print Publication: 2022).