Výsledky vyhledávání - "2,4 thiazolidinedione derivative"

Effect of natural products on commercial oral antidiabetic drugs in enhancing 2-deoxyglucose uptake by 3T3-L1 adipocytes

Autor: Pranav Kumar Prabhakar, Mukesh Doble

Publikováno v: Therapeutic Advances in Endocrinology and Metabolism, Vol 2 (2011)

Objective: The management of diabetes with insulin and synthetic oral hypoglycemic drugs (OHDs) can produce serious side effects and in addition fails to prevent diabetes-related complications in many patients. A new diabetes management strategy is n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d81c08a6e9eee73ca921a1078ffcbb
https://doi.org/10.1177/2042018811411356

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Phthalates efficiently bind to human peroxisome proliferator activated receptor and retinoid X receptor ?, ?, ? subtypes: An in silico approach

Autor: Sarath Josh, M.K., Pradeep, S., Vijayalekshmi Amma, K.S., Balachandran, S., Abdul Jaleel, U.C., Doble, M., Spener, F., Benjamin, S.

Publikováno v: IndraStra Global.

This exhaustive in silico study looks into the molecular interactions of phthalates and their metabolites with human peroxisome proliferator-activated receptor (hPPAR) and retinoid X receptor (hRXR) ?, ? and ? subtypes - the nuclear receptor proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=issn23813652::cbed98f0f71c299a77f3dd0ccd38daac
http://hdl.handle.net/11717/15361

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Comparative genotoxic and cytotoxic effects of the oral antidiabetic drugs sitagliptin, rosiglitazone, and pioglitazone in patients with type-2 diabetes: A cross-sectional, observational pilot study

Autor: Soner Cander, Dilek Yilmaz, Ozen Oz Gul, Nilufer Cinkilic, Ozgur Vatan, Canan Ersoy, Ercan Tuncel, Cuma Bulent Gul

This cross-sectional, observational pilot. study was designed to investigate the frequency of different endpoints of genotoxicity (sister-chromatid exchange, total chromosome aberrations, and micronucleus formation) and cytotoxicity (mitotic index, r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181df4e57d25c63e67ea8fb6cc904880
http://hdl.handle.net/11452/29781

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Interaction of cinnamic acid derivatives with commercial hypoglycemic drugs on 2-deoxyglucose uptake in 3T3-L1 adipocytes

Autor: Mukesh Doble, Pranav Kumar Prabhakar

Publikováno v: Journal of agricultural and food chemistry. 59(18)

Hydroxycinnamic acid derivatives are naturally occurring substances found in fruits, vegetables, and flowers and are consumed as dietary phenolic compounds. The effect of cinnamic acid, ferulic acid, p-coumaric acid, eugenol, chlorogenic acid, and ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ceab36b5166fb900442eee5831cb06
https://pubmed.ncbi.nlm.nih.gov/21870829

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Metformin monotherapy for type 2 diabetes mellitus

Autor: Saenz A., Fernandez-Esteban I., Mataix A., Ausejo Segura M., Roqué i Figuls M., Moher D.

Publikováno v: Cochrane Database of Systematic Reviews
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Background: Metformin is an anti-hyperglycaemic agent used for the treatment of type 2 diabetes mellitus. Type 2 diabetes may present long-term complications: micro- (retinopathy, nephropathy and neuropathy) and macrovascular (stroke, myocardial infa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ff80754829e66b599b81f45c4667c4bc
https://www.scopus.com/inward/record.uri?eid=2-s2.0-32944456100&doi=10.1002/14651858.CD002966.pub3&partnerID=40&md5=dd36873a738a2a9b5e92d9805eadedc4

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