Zobrazeno 1 - 10
of 16
pro vyhledávání: '"1O2, singlet oxygen"'
Autor:
Jason R. Cook, Jeanne Duong, Srivalleesha Mallidi, Nashielli Diaz, Kimberly A. Homan, Marvin Xavierselvan
Publikováno v:
Photoacoustics, Vol 25, Iss, Pp 100306-(2022)
Photoacoustics
Photoacoustics
Photodynamic therapy (PDT) is a well-known cancer therapy that utilizes light to excite a photosensitizer and generate cytotoxic reactive oxygen species (ROS). The efficacy of PDT primarily depends on the photosensitizer and oxygen concentration in t
Autor:
Swarnmala Samal, Mukesh Meena
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 6, Iss, Pp 745-758 (2019)
Toxicology Reports, Vol 6, Iss, Pp 745-758 (2019)
Graphical abstract
Highlights • Alternaria is responsible to cause pathogenic diseases on several crops. • Alternaria species produce several types of host-specific and non-host-specific toxins. • HSTs have devastating effects on host plan
Highlights • Alternaria is responsible to cause pathogenic diseases on several crops. • Alternaria species produce several types of host-specific and non-host-specific toxins. • HSTs have devastating effects on host plan
Autor:
Nicolai Lehnert, Dhiman Maitra, Stephen W. Ragsdale, Laure Rittié, M. Bishr Omary, Alexey I. Nesvizhskii, Haoming Zhang, Matthew W. Wolf, Harald Herrmann, Venkatesha Basrur, Rani Richardson, Yoichi Osawa, Eric L. Carter
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 4, Pp 659-682.e1 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Porphyrias are caused by porphyrin accumulation resulting from defects in the heme biosynthetic pathway that typically lead to photosensitivity and possible end-stage liver disease with an increased risk of hepatocellular carcinoma.
Autor:
Juliana Bragazzi Cunha, Jordan A. Shavit, Herbert L. Bonkovsky, Dhiman Maitra, Jared S. Elenbaas, M. Bishr Omary
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 4, Pp 535-548 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Genetic porphyrias comprise eight diseases caused by defects in the heme biosynthetic pathway that lead to accumulation of heme precursors. Consequences of porphyria include photosensitivity, liver damage and increased risk of hepatocellular carcinom
Autor:
Haiyan Zheng, Dhiman Maitra, M. Bishr Omary, Benjamin M. Pinsky, Ruma Banerjee, Amenah Soherawardy
Publikováno v:
The Journal of Biological Chemistry
Porphyrias are rare blood disorders caused by genetic defects in the heme biosynthetic pathway and are associated with the accumulation of high levels of porphyrins that become cytotoxic. Porphyrins, due to their amphipathic nature, spontaneously ass
Publikováno v:
Biochimica et Biophysica Acta. Molecular Basis of Disease
SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) also in pregnant women. Infection in pregnancy leads to maternal and placental functional alterations. Pregnant women with vascular defects such as preeclampsia show high susceptibility to SARS-Co
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 5, Iss 4, Pp 285-299 (2015)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The Keap1–Nrf2–ARE pathway is an important antioxidant defense mechanism that protects cells from oxidative stress and the Keap1–Nrf2 protein–protein interaction (PPI) has become an important drug target to upregulate the expression of ARE-co
Publikováno v:
Redox Biology
Photodynamic therapy (PDT) against cancer has gained attention due to the successful outcome in some cancers, particularly those on the skin. However, there have been limitations to PDT applications in deep cancers and, occasionally, PDT treatment re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a2a85eacc8fcbea6efea6778c8ccbb
https://escholarship.org/uc/item/5t4270wx
https://escholarship.org/uc/item/5t4270wx
Akademický článek
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Autor:
Reto Brem, Peter Karran
Publikováno v:
DNA Repair
Solar UVB is carcinogenic. Nucleotide excision repair (NER) counteracts the carcinogenicity of UVB by excising potentially mutagenic UVB-induced DNA lesions. Despite this capacity for DNA repair, non-melanoma skin cancers and apparently normal sun-ex