Zobrazeno 1 - 10
of 550
pro vyhledávání: '"19F NMR"'
Autor:
Sophia Li, Emma Wang, Leia Pei, Sourodeep Deb, Prashanth Prabhala, Sai Hruday Reddy Nara, Raina Panda, Shiven Eltepu, Marx Akl, Larry McMahan, Edward Njoo
Publikováno v:
Artificial Intelligence Chemistry, Vol 2, Iss 2, Pp 100078- (2024)
The introduction of fluorine in compounds plays a crucial role in drug development as it greatly influences their final pharmacokinetic and dynamic properties. Due to the prevalence of fluorine in FDA-approved drugs in recent years, identifying the m
Externí odkaz:
https://doaj.org/article/8c8bb13b058d48de96b0962d2a1bb63a
Enantiodifferentiation of chiral diols and diphenols via recognition-enabled chromatographic 19F NMR
Publikováno v:
Magnetic Resonance Letters, Vol 4, Iss 4, Pp 200112- (2024)
A novel and efficient method for distinguishing between chiral diols and diphenols has been established through the use of 19F NMR spectroscopy. Central to this system's efficacy is a chiral amine, strategically modified with a CF3 group. This amine
Externí odkaz:
https://doaj.org/article/964687bd19aa45758edc197b26b43e25
Autor:
Peiyao Chen, Shuang Zhuang, Weiguang Chen, Zhijian Chen, Rongzhen Li, Fangyu Chen, Tingting Jiang, Xiaobin Fu
Publikováno v:
Magnetic Resonance Letters, Vol 4, Iss 3, Pp 100097- (2024)
Aqueous film-forming foams (AFFFs) are the primary source of toxic perfluoroalkyl and polyfluoroalkyl substances (PFAS) in wastewater. Thus, it is urgent to develop a facile and fast method for identifying fluorosurfactants in commercially available
Externí odkaz:
https://doaj.org/article/3d51108973734123afeec1f8522b1a16
Autor:
Vladislav V. Komarov, Vyacheslav I. Krasnov, Victor M. Karpov, Dmitriy A. Parkhomenko, Tatyana V. Mezhenkova
Publikováno v:
Molbank, Vol 2024, Iss 3, p M1842 (2024)
The title compound was synthesized from perfluoro-1-ethyltetralin and 1,2,3,4-tetrafluorobenzene under the action of antimony pentafluoride as a mixture of cis- and trans-isomers in a 71% isolated yield. The structure and cis-/trans-configuration of
Externí odkaz:
https://doaj.org/article/ad49f6673308492f93afb1d70ef37419
Publikováno v:
Inorganics, Vol 12, Iss 7, p 187 (2024)
When synthesizing the versatile precursors (NMe4)[Ni(CF3)3(MeCN)] we recently encountered the problem that marked amounts of C2F5 were incorporated instead of CF3 under the chosen reaction conditions forming mixed-ligand nickelates [Ni(CF3)x(C2F5)y(M
Externí odkaz:
https://doaj.org/article/acaeb62823f24bf9a85dcd3ac5b95e35
Autor:
Hesna Kara, Alexander Axer, Frederick W. Muskett, Carlos J. Bueno-Alejo, Vasileios Paschalis, Andrea Taladriz-Sender, Sumera Tubasum, Marina Santana Vega, Zhengyun Zhao, Alasdair W. Clark, Andrew J. Hudson, Ian C. Eperon, Glenn A. Burley, Cyril Dominguez
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Protein-RNA interactions are central to numerous cellular processes. In this work, we present an easy and straightforward NMR-based approach to determine the RNA binding site of RNA binding proteins and to evaluate the binding of pairs of proteins to
Externí odkaz:
https://doaj.org/article/2051e50dad5a4945b5af04fd03395abe
Publikováno v:
Журнал органічної та фармацевтичної хімії, Vol 21, Iss 2, Pp 21-28 (2023)
Aim. To analyze commercially available fluorine containing compounds for the possibility of their use in the 19F NMR FAXS method. Materials and methods. The selection of fluorine-containing fragments for the study was performed using 3.9 million ins
Externí odkaz:
https://doaj.org/article/47c7c33a962d4ca7a76185e73677472b
Autor:
Deepak Kumar, Samanwita Pal
Publikováno v:
Magnetic Resonance Letters, Vol 3, Iss 2, Pp 197-205 (2023)
The present study aims to investigate the motional dynamics of risperidone within polylactic co-glycolic acid (PLGA) microsphere by employing solution state 1H and 19F nuclear magnetic resonance (NMR) measurements. Risperidone, a second-generation fl
Externí odkaz:
https://doaj.org/article/ce8190b71c7347a5bfa611045b87c8c1
Autor:
Leonhard Geist, Paola Martinelli, Shereena Mohideen-Ali, Patrick Werni, Gerhard Fischer, Julian E. Fuchs, Klaus Rumpel, Moriz Mayer
Publikováno v:
Journal of Magnetic Resonance Open, Vol 12, Iss , Pp 100075- (2022)
Inhibition of the exonuclease activity of Three-prime Repair EXonuclease 1 (TREX1) has emerged as a potential novel immunotherapeutic strategy. Herein we describe our screening approach to find initial low-affinity fragment hits for TREX1 from our 19
Externí odkaz:
https://doaj.org/article/89944a6f4a7c4c1e9a8c96a64ec685de
Publikováno v:
Journal of Magnetic Resonance Open, Vol 12, Iss , Pp 100070- (2022)
1H and 19F NMR methods based on chemical shift measurements of different hydrogen bond donors used for quantifying hydrogen bond strength were analyzed and compared. The extracted values from these different methods are shown to be highly correlated
Externí odkaz:
https://doaj.org/article/66abaf4598454b999f97aeb4404585d9