Zobrazeno 1 - 10
of 189
pro vyhledávání: '"18F-Fluoromisonidazole"'
Autor:
Emiko Desvaux, Alan Courteau, Pierre-Simon Bellaye, Mélanie Guillemin, Camille Drouet, Paul Walker, Bertrand Collin, Richard A. Decréau
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-6 (2018)
Abstract Purpose Molecular imaging techniques visualise biomarkers for both drug development and personalised medicine. In this field, Cherenkov luminescence imaging (CLI) seems to be very attractive by allowing imaging with clinical PET radiotracers
Externí odkaz:
https://doaj.org/article/26005c11dfde4e85b19e399fcb8ad5f7
Autor:
Aya Asano, Shigeto Ueda, Ichiei Kuji, Tomohiko Yamane, Hideki Takeuchi, Eiko Hirokawa, Ikuko Sugitani, Hiroko Shimada, Takahiro Hasebe, Akihiko Osaki, Toshiaki Saeki
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-8 (2018)
Abstract Background Hypoxia is a key driver of cancer progression. We evaluated the prognostic impact of 18F-fluoromisonidazole (FMISO) prior to treatment in patients with breast cancer. Methods Forty-four patients with stage II/III primary breast ca
Externí odkaz:
https://doaj.org/article/71ea1e4447a34fafa8bdccd6ca52018a
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-4 (2018)
Abstract Background Quantitative imaging can facilitate patient stratification in clinical trials. The hypoxia-activated prodrug evofosfamide recently failed a phase III trial in pancreatic cancer. However, the study did not attempt to select for pat
Externí odkaz:
https://doaj.org/article/9677037b00144563a5848dafe17d01ee
Autor:
Kilian Krzysztof, Rogulski Zbigniew, Cheda Łukasz, Drzał Agnieszka, Gerszewska Marina, Cudny Michał, Elas Martyna
Publikováno v:
Nukleonika, Vol 61, Iss 2, Pp 219-223 (2016)
A method of automated synthesis of [18F]fluoromisonidazole ([18F]FMISO) for application in preclinical studies on small animals was presented. A remote-controlled synthesizer Synthra RNplus was used for nucleophilic substitution of NITTP (1′-(2′-
Externí odkaz:
https://doaj.org/article/ac99132527aa43d6b969de20f348ce05
Akademický článek
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Akademický článek
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Autor:
Masahiro Hiraoka, Kohei Sano, Yoichi Shimizu, Michio Yoshimura, Yuji Nakamoto, Mitsue Kawamura, Takayoshi Ishimori, Takashi Mizowaki
Publikováno v:
Molecular Imaging and Biology. 23:597-603
Positron emission tomography (PET)/computed tomography (CT) using 18F-fluoromisonidazole (FMISO) has been used as an imaging tool for tumour hypoxia. However, it remains unclear whether they are useful when scanning is performed earlier, e.g. at 2-h
Autor:
Eisuke Ueshima, Kayako Isohashi, Koji Sasaki, Takuya Okada, Koji Maruyama, Masato Yamaguchi, Munenobu Nogami, Takeshi Ueha, Yasukazu Kanai, Hayato Ikeda, Jun Hatazawa, Tomoyuki Gentsu, Takamichi Murakami, Keitaro Sofue, Koji Sugimoto, Yoshitada Sakai
Publikováno v:
Oncology Letters
Carbon dioxide (CO2) treatment is reported to have an antitumor effect owing to the improvement in intratumoral hypoxia. Previous studies were based on histological analysis alone. In the present study, the improvement in intratumoral hypoxia by perc
Autor:
Nagara Tamaki, Toshihisa Anzai, Noriko Oyama-Manabe, Kohsuke Kudo, Kenji Hirata, Hiroshi Ohira, Keiichi Magota, Osamu Manabe, Sho Furuya, Masanao Naya, Tadao Aikawa, Ichizo Tsujino, Yuji Kuge, Tohru Shiga, Kazuhiro Koyanagawa
Publikováno v:
Journal of Nuclear Cardiology. 28:2141-2148
18F-fluoromisonidazole (FMISO) is a hypoxia positron emission tomography (PET) tracer. Here, we evaluated cardiac and extra-cardiac sarcoidosis using both FMISO and 18F-fluorodeoxyglucose (FDG) PET/CT in a prospective cohort of patients with sarcoido
Autor:
Takuya Toyonaga, Shunsuke Terasaka, Kohsuke Kudo, Sho Furuya, Shigeru Yamaguchi, Keiichi Magota, Tohru Shiga, Nagara Tamaki, Osamu Manabe, Hiroyuki Kobayashi, Kentaro Kobayashi, Yuji Kuge, Kenji Hirata
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 47:1833-1842
18F-fluoromisonidazole (18F-FMISO) is the most widely used positron emission tomography (PET) tracer for imaging tumor hypoxia. Previous reports suggested that the time from injection to the scan may affect the assessment of 18F-FMISO uptake. Herein,