Zobrazeno 1 - 10
of 26
pro vyhledávání: '"17beta-HSD 1"'
Publikováno v:
Cancer letters. 243(1)
Expression of the estrogen-synthesizing genes aromatase, steroid sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type1 (17beta-HSD(1)) has been shown to be up-regulated in primary breast cancer tissue but their expression status in metastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f372fac4e4a019d65a9a1a35e37d49
https://pubmed.ncbi.nlm.nih.gov/16556483
https://pubmed.ncbi.nlm.nih.gov/16556483
Autor:
Irahara N; Department of Breast and Endocrine Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita-shi, Osaka 565-0871, Japan., Miyoshi Y, Taguchi T, Tamaki Y, Noguchi S
Publikováno v:
Cancer letters [Cancer Lett] 2006 Nov 08; Vol. 243 (1), pp. 23-31. Date of Electronic Publication: 2006 Mar 23.
Publikováno v:
Geburtshilfe und Frauenheilkunde. 68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f013712bc364fb17c74d42fc90418ba5
https://doi.org/10.1055/s-2008-1075767
https://doi.org/10.1055/s-2008-1075767
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Klein, Tobias
Comparing biological activities and thermodynamic profiles obtained for one compound toward proteins, differing only in few residues is a promising strategy to increase the knowledge of protein-ligand interactions and active site topologies thereby e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a2c769eed0765c40196341020f8eb2
Autor:
Mindnich, R.1, Adamski, J. adamski@gsf.de
Publikováno v:
Journal of Steroid Biochemistry & Molecular Biology. May2007, Vol. 104 Issue 3-5, p334-339. 6p.
Publikováno v:
Journal of Endocrinology; January 1999, Vol. 160 Issue: 1 p119-126, 8p
Autor:
Gabriele Möller, Bettina Husen, Dorota Kowalik, Leena Hirvelä, Dariusz Plewczynski, Leszek Rychlewski, Josef Messinger, Hubert Thole, Jerzy Adamski
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10969 (2010)
Steroid-related cancers can be treated by inhibitors of steroid metabolism. In searching for new inhibitors of human 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD 1) for the treatment of breast cancer or endometriosis, novel substances based
Externí odkaz:
https://doaj.org/article/06b4b6d915cf4e4aa8a692666c9b6054
Autor:
Chen-Yan Zhang1,2, Jiong Chen3, Da-Chuan Yin2, Sheng-Xiang Lin1,4 sheng-xiang.lin@crchul.ulaval.ca
Publikováno v:
PLoS ONE. Jan2012, Vol. 7 Issue 1, p1-7. 7p.
Autor:
Dorota Kowalik, Walter Elger, Andrea Rosinus, Dominga Deluca, Gabriele Möller, Peter Droescher, Christian Gege, Alexander Hillisch, Olaf Peters, Jerzy Adamski
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6740-6744
In search for specific drugs against steroid-dependent cancers we have developed a novel set of potent inhibitors of steroidogenic human 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD 1). The X-ray structure of 17beta-HSD 1 in complex with es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c99dcb529fa4520d03d3fe159135b60
https://doi.org/10.1016/j.bmcl.2009.09.113
https://doi.org/10.1016/j.bmcl.2009.09.113