Green method for 17-hydroxyprogesterone extraction and determination using PDMS stir bar sorptive extraction coupled with HPLC: optimization by response surface methodology

Autor: Maedeh Noori, Zahra Talebpour

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Abstract Quantifying small amounts of the 17-hydroxyprogesterone in various matrix is crucial for different purposes. In this study, a commercial polydimethylsiloxane stir bar was used to extract hormone from water and urine samples. Analysis was per

Externí odkaz: https://doaj.org/article/0892e9f977da409a87467fe33064362a

Adrenal adenoma secreting 17-hydroxyprogesterone mimicking non-classical 21-hydroxylase deficiency

Autor: Beata Woźniak, Dorota Leszczyńska, Alicja Szatko, Karolina Nowak, Radosław Samsel, Anna Siejka, Lucyna Papierska, Wojciech Zgliczyński, Henrik Falhammar, Piotr Glinicki

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

In adrenal steroidogenesis, 17-hydroxyprogesterone (17-OHP) is a substrate for 21-hydroxylase, one of the crucial enzymes of the cortisol and aldosterone biosynthesis pathway. Thus, measurement serum 17-OHP concentration is used when the diagnosis of

Externí odkaz: https://doaj.org/article/2df03d3f3cea474d8972cdffaf47cd47

Diurnal 11-ketotestosterone and 17-hydroxyprogesterone saliva profiles in paediatric classical congenital adrenal hyperplasia.

Autor: Dubinski, Ilja, Bechtold-Dalla Pozza, Susanne, Bidlingmaier, Martin, Hawley, James, Keevil, Brian, Kunz, Sonja, Nowotny, Hannah Franziska, Reisch, Nicole, Schiergens, Katharina, Tschaidse, Lea, Schmidt, Heinrich

Publikováno v: Journal of Pediatric Endocrinology & Metabolism; May2024, Vol. 37 Issue 5, p419-424, 6p

Adrenal adenoma secreting 17-hydroxyprogesterone mimicking non-classical 21-hydroxylase deficiency.

Autor: Woźniak B; Department of Endocrinology, Centre of Postgraduate Medical Education, Warsaw, Poland., Leszczyńska D; Department of Endocrinology, Centre of Postgraduate Medical Education, Warsaw, Poland., Szatko A; Department of Endocrinology, Centre of Postgraduate Medical Education, Warsaw, Poland.; EndoLab Laboratory, Centre of Postgraduate Medical Education, Warsaw, Poland., Nowak K; Department of Endocrinology, Centre of Postgraduate Medical Education, Warsaw, Poland., Samsel R; Department of Surgery, Clinic of Surgical Oncology and Neuroendocrine Tumors, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Siejka A; Clinical Biochemistry Department, The Children's Memorial Health Institute, Warsaw, Poland., Papierska L; Department of Endocrinology, Centre of Postgraduate Medical Education, Warsaw, Poland., Zgliczyński W; Department of Endocrinology, Centre of Postgraduate Medical Education, Warsaw, Poland., Falhammar H; Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Glinicki P; Department of Endocrinology, Centre of Postgraduate Medical Education, Warsaw, Poland.; EndoLab Laboratory, Centre of Postgraduate Medical Education, Warsaw, Poland.

Publikováno v: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 Nov 21; Vol. 15, pp. 1499836. Date of Electronic Publication: 2024 Nov 21 (Print Publication: 2024).

The impact of neonatal 17-hydroxyprogesterone cutoff determination in a public newborn screening program for congenital adrenal hyperplasia in Southern Brazil: 3 years’ experience

Autor: Simone Martins de Castro, Paloma Wiest, Poli Mara Spritzer, Cristiane Kopacek

Publikováno v: Endocrine Connections, Vol 12, Iss 12, Pp 1-9 (2023)

Congenital adrenal hyperplasia (CAH) occurs due to enzyme defects in adrenal steroidogenesis. The 21-hydroxylase deficiency accounts for 90–95% of cases, triggering accumulation of 17-hydroxyprogesterone (17-OHP). Early diagnosis through neonatal s

Externí odkaz: https://doaj.org/article/f6faf3bfb1a74e8bb44b1fd7b6526f1f