Zobrazeno 1 - 10
of 1 151
pro vyhledávání: '"1605 Organic Chemistry"'
Autor:
Andrea Dalle Vedove, Giulia Cazzanelli, Laurent Batiste, Jean-Rémy Marchand, Dimitrios Spiliotopoulos, Jessica Corsi, Vito Giuseppe D’Agostino, Amedeo Caflisch, Graziano Lolli
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1434-1443
BAZ2A is an epigenetic regulator affecting transcription of ribosomal RNA. It is overexpressed in aggressive and recurrent prostate cancer, promoting cellular migration. Its bromodomain is characterized by a shallow and difficult-to-drug pocket. Here
Autor:
Betts, Harley D, Ong, Yih Ching, Anghel, Nicoleta, Keller, Sarah, Karges, Johannes, Voutsara, Niovi, Müller, Joachim, Manoury, Eric, Blacque, Olivier, Cariou, Kevin, Hemphill, Andrew, Gasser, Gilles
Publikováno v:
Organometallics
Organometallics, 2022, ⟨10.1021/acs.organomet.2c00204⟩
Organometallics, 2022, ⟨10.1021/acs.organomet.2c00204⟩
International audience; Toxoplasmosis is an infection contracted by exposure to Toxoplasma gondii and can have deleterious health effects on pregnant women and their children. Current treatments for the infection are complex and have considerable und
Autor:
Grayfer, Tatyana D, Yamani, Khalil, Jung, Erik, Chesnokov, Gleb A, Ferrara, Isabella, Hsiao, Chien-Chi, Georgiou, Antri, Michel, Jeremy, Bailly, Aurélien, Sieber, Simon, Eberl, Leo, Gademann, Karl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382b3f03f24da91709b5ea292e6994d2
https://doi.org/10.5167/uzh-233963
https://doi.org/10.5167/uzh-233963
Autor:
Christian Vahlensieck, Cora Sandra Thiel, Meret Mosimann, Timothy Bradley, Fabienne Caldana, Jennifer Polzer, Beatrice Astrid Lauber, Oliver Ullrich
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1351
Cellular effects of hypergravity have been described in many studies. We investigated the transcriptional dynamics in Jurkat T cells between 20 s and 60 min of 9 g hypergravity and characterized a highly dynamic biphasic time course of gene expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8022dd4c530aedd39d07427e38d2f832
https://www.zora.uzh.ch/id/eprint/231481/
https://www.zora.uzh.ch/id/eprint/231481/
Publikováno v:
Molecules; Volume 28; Issue 1; Pages: 45
Molecules, 28 (1)
Molecules, 28 (1)
Environmental volatile organic compounds (VOCs) from the ambient air potentially influence on-line breath analysis measurements by secondary electrospray ionization high-resolution mass spectrometry (SESI-HRMS). The aim of this study was to investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54fc4671b1149286758bdd2e2238a098
https://doi.org/10.5167/uzh-229478
https://doi.org/10.5167/uzh-229478
Autor:
Jiawei Zhang, Lan Liu, Yaxuan Zhang, Yuan Yuan, Zhijuan Miao, Kaili Lu, Xiaojie Zhang, Ruiqing Ni, Haibing Zhang, Yuwu Zhao, Xiuzhe Wang
Publikováno v:
Redox Biology, 58
Diabetes mellitus is associated with cognitive impairment characterized by memory loss and cognitive inflexibility. Recent studies have revealed that ChemR23 is implicated in both diabetes mellitus and Alzheimer's disease. However, the impact of Chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1b3765c1202640fb70cdb8225c289d
https://www.zora.uzh.ch/id/eprint/225199/
https://www.zora.uzh.ch/id/eprint/225199/
Autor:
Simone Fenk, Elizaveta V. Melnikova, Anastasia A. Anashkina, Yuri M. Poluektov, Pavel I. Zaripov, Vladimir A. Mitkevich, Yaroslav V. Tkachev, Lars Kaestner, Giampaolo Minetti, Heimo Mairbäurl, Jeroen S. Goede, Alexander A. Makarov, Irina Yu Petrushanko, Anna Bogdanova
Fast changes in environmental oxygen availability translate into shifts in mitochondrial free radical production. An increase in intraerythrocytic reduced glutathione (GSH) during deoxygenation would support the detoxification of exogenous oxidants r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aac2dcd0c5c76e372eea2ffe515523f
https://www.zora.uzh.ch/id/eprint/231071/
https://www.zora.uzh.ch/id/eprint/231071/
Autor:
Al-Wahaibi, Lamya H, Alagappan, Kowsalya, Blacque, Olivier, Mohamed, Ahmed A B, Hassan, Hanan M, Percino, María Judith, El-Emam, Ali A, Thamotharan, Subbiah
Publikováno v:
Molecules; Volume 27; Issue 23; Pages: 8425
Two biologically active adamantane-linked hydrazine-1-carbothioamide derivatives, namely 2-(adamantane-1-carbonyl)-N-(tert-butyl)hydrazine-1-carbothioamide) 1 and 2-(adamantane-1-carbonyl)-N-cyclohexylhydrazine-1-carbothioamide 2, have been synthesiz