Zobrazeno 1 - 10
of 47
pro vyhledávání: '"14/35"'
Autor:
Ludek Koreny, Brandon N. Mercado-Saavedra, Christen M. Klinger, Konstantin Barylyuk, Simon Butterworth, Jennifer Hirst, Yolanda Rivera-Cuevas, Nathan R. Zaccai, Victoria J. C. Holzer, Andreas Klingl, Joel B. Dacks, Vern B. Carruthers, Margaret S. Robinson, Simon Gras, Ross F. Waller
Acknowledgements: This work was supported by the Wellcome Trust, United Kingdom, Investigator award 214298/Z/18/Z to R.F.W., a Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) grant 464878930 to S.G., and a DFG Equipment grant INST 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d2d5773dfd5d2a6bf8621c64d002b9
Autor:
C. Albert, L. Bracaglia, A. Koide, J. DiRito, T. Lysyy, L. Harkins, C. Edwards, O. Richfield, J. Grundler, K. Zhou, E. Denbaum, G. Ketavarapu, T. Hattori, S. Perincheri, J. Langford, A. Feizi, D. Haakinson, S. A. Hosgood, M. L. Nicholson, J. S. Pober, W. M. Saltzman, S. Koide, G. T. Tietjen
Funder: U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
Funder: American Association for the Study of Liver Diseases (AASLD); doi: https://doi.org/10.13039/100005347
Vascular
Funder: American Association for the Study of Liver Diseases (AASLD); doi: https://doi.org/10.13039/100005347
Vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0a45c754fc5f3ce581000952f7d946
https://www.repository.cam.ac.uk/handle/1810/342002
https://www.repository.cam.ac.uk/handle/1810/342002
Autor:
Roberto Carlos Segura, Clemens Cabernard, Nicole MynYi Lee, Jennifer Taylor, Chantal Roubinet, Bharath Sunchu
Hybrid cells derived through fertilization or somatic cell fusion recognize and separate chromosomes of different origins. The underlying mechanisms are unknown but could prevent aneuploidy and tumor formation. Here, we acutely induce fusion between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214d13eda29285ded549f052fe70c1ec
https://www.repository.cam.ac.uk/handle/1810/342367
https://www.repository.cam.ac.uk/handle/1810/342367
Autor:
Yu Yuan, Dawid Jaślan, Taufiq Rahman, Stephen R. Bolsover, Vikas Arige, Larry E. Wagner, Carla Abrahamian, Rachel Tang, Marco Keller, Jonas Hartmann, Anna S. Rosato, Eva-Maria Weiden, Franz Bracher, David I. Yule, Christian Grimm, Sandip Patel
Two-pore channels are endo-lysosomal cation channels with malleable selectivity filters that drive endocytic ion flux and membrane traffic. Here we show that TPC2 can differentially regulate its cation permeability when co-activated by its endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71859e25e0ebfbb43c889752e0fbccca
https://www.repository.cam.ac.uk/handle/1810/339751
https://www.repository.cam.ac.uk/handle/1810/339751
Autor:
Alejandro Carnicer-Lombarte, James W. Fawcett, Bart Nieuwenhuis, Sam Hilton, Joost Verhaagen, Barbara Hobo, Barbara Haenzi
Publikováno v:
Gene Therapy
Gene Therapy, 28, 56-74. Nature Publishing Group
Gene Therapy, 28(1-2), 56-74. Nature Publishing Group
Nieuwenhuis, B, Haenzi, B, Hilton, S, Carnicer-Lombarte, A, Hobo, B, Verhaagen, J & Fawcett, J W 2021, ' Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract : comparison of four promoters ', Gene Therapy, vol. 28, no. 1-2, pp. 56-74 . https://doi.org/10.1038/s41434-020-0169-1
Gene Therapy, 28, 56-74. Nature Publishing Group
Gene Therapy, 28(1-2), 56-74. Nature Publishing Group
Nieuwenhuis, B, Haenzi, B, Hilton, S, Carnicer-Lombarte, A, Hobo, B, Verhaagen, J & Fawcett, J W 2021, ' Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract : comparison of four promoters ', Gene Therapy, vol. 28, no. 1-2, pp. 56-74 . https://doi.org/10.1038/s41434-020-0169-1
Funder: This research was funded by a Nathalie Rose Barr award (NRB110) from the International Spinal Research Trust, and support from Medical Research Council (MR/R004544/1 & MR/R004463/1), NWO (013-16-002), Czech Ministry of Education (CZ.02.1.01/0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9571c9d4b325646d814e8ee8b8e9ef35
https://doi.org/10.1038/s41434-020-0169-1
https://doi.org/10.1038/s41434-020-0169-1
Autor:
Steurer, Barbara, Janssens, Roel C, Geijer, Marit E, Aprile-Garcia, Fernando, Geverts, Bart, Theil, Arjan F, Hummel, Barbara, Van Royen, Martin E, Evers, Bastiaan, Bernards, René, Houtsmuller, Adriaan B, Sawarkar, Ritwick, Marteijn, Jurgen
Funder: Oncode Institute
The precise regulation of RNA Polymerase II (Pol II) transcription after genotoxic stress is crucial for proper execution of the DNA damage-induced stress response. While stalling of Pol II on transcription-blocking lesi
The precise regulation of RNA Polymerase II (Pol II) transcription after genotoxic stress is crucial for proper execution of the DNA damage-induced stress response. While stalling of Pol II on transcription-blocking lesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834a9b8389b04eed753b66e9255fd0fa
https://www.repository.cam.ac.uk/handle/1810/339497
https://www.repository.cam.ac.uk/handle/1810/339497
Autor:
Yang Zhang, Laura Garcia-Ibanez, Carolin Ulbricht, Laurence S. C. Lok, Jeremy A. Pike, Jennifer Mueller-Winkler, Thomas W. Dennison, John R. Ferdinand, Cameron J. M. Burnett, Juan C. Yam-Puc, Lingling Zhang, Raul Maqueda Alfaro, Yousuke Takahama, Izumi Ohigashi, Geoffrey Brown, Tomohiro Kurosaki, Victor L. J. Tybulewicz, Antal Rot, Anja E. Hauser, Menna R. Clatworthy, Kai-Michael Toellner
Publikováno v:
Nature Communications. 13
Infection or vaccination leads to the development of germinal centers (GC) where B cells evolve high affinity antigen receptors, eventually producing antibody-forming plasma cells or memory B cells. Here we follow the migratory pathways of B cells em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25548d1e4f1affa2d95453c431a6768
https://doi.org/10.1038/s41467-022-29978-y
https://doi.org/10.1038/s41467-022-29978-y
Autor:
Jason S. L. Yu, Clara Correia-Melo, Francisco Zorrilla, Lucia Herrera-Dominguez, Mary Y. Wu, Johannes Hartl, Kate Campbell, Sonja Blasche, Marco Kreidl, Anna-Sophia Egger, Christoph B. Messner, Vadim Demichev, Anja Freiwald, Michael Mülleder, Michael Howell, Judith Berman, Kiran R. Patil, Mohammad Tauqeer Alam, Markus Ralser
Publikováno v:
Nature Microbiology
Funder: United Arab Emirates University (UAEU); doi: https://doi.org/10.13039/501100006013
Microbial communities are composed of cells of varying metabolic capacity, and regularly include auxotrophs that lack essential metabolic pathways. Throug
Microbial communities are composed of cells of varying metabolic capacity, and regularly include auxotrophs that lack essential metabolic pathways. Throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a320f8b9f32dc7be966627c6272171
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Defects in chromosome-microtubule attachment can cause chromosomal instability (CIN), frequently associated with infertility and aggressive cancers. Chromosome-microtubule attachment is mediated by a large macromolecular structure, the kinetochore. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbbd287c4dc7bebf9e03789798ad417
https://www.repository.cam.ac.uk/handle/1810/333073
https://www.repository.cam.ac.uk/handle/1810/333073
Publikováno v:
Nature Structural & Molecular Biology
Many regulatory PPP1R subunits join few catalytic PP1c subunits to mediate phosphoserine and phosphothreonine dephosphorylation in metazoans. Regulatory subunits engage the surface of PP1c, locally affecting flexible access of the phosphopeptide to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3922eb945c18d759d1bcc706e6bfaac5
https://www.repository.cam.ac.uk/handle/1810/329189
https://www.repository.cam.ac.uk/handle/1810/329189