Zobrazeno 1 - 10
of 73
pro vyhledávání: '"13/51"'
Autor:
Dick W. Zijlmans, Irene Talon, Sigrid Verhelst, Adam Bendall, Karlien Van Nerum, Alok Javali, Andrew A. Malcolm, Sam S. F. A. van Knippenberg, Laura Biggins, San Kit To, Adrian Janiszewski, Danielle Admiraal, Ruth Knops, Nikky Corthout, Bradley P. Balaton, Grigorios Georgolopoulos, Amitesh Panda, Natarajan V. Bhanu, Amanda J. Collier, Charlene Fabian, Ryan N. Allsop, Joel Chappell, Thi Xuan Ai Pham, Michael Oberhuemer, Cankat Ertekin, Lotte Vanheer, Paraskevi Athanasouli, Frederic Lluis, Dieter Deforce, Joop H. Jansen, Benjamin A. Garcia, Michiel Vermeulen, Nicolas Rivron, Maarten Dhaenens, Hendrik Marks, Peter J. Rugg-Gunn, Vincent Pasque
Publikováno v:
Nature Cell Biology, 24, pp. 858-871
Nature Cell Biology, 24, 858-871
Nature Cell Biology
NATURE CELL BIOLOGY
Nature Cell Biology, 24, 858-871
Nature Cell Biology
NATURE CELL BIOLOGY
Funder: The Marks lab is supported by an NWO-XS grant
Funder: M.V. is part of the Oncode Institute, which is partly funded by the Dutch Cancer Society
Funder: D.W.Z. is part of the Oncode Institute, which is partly funded by the Dutch Cance
Funder: M.V. is part of the Oncode Institute, which is partly funded by the Dutch Cancer Society
Funder: D.W.Z. is part of the Oncode Institute, which is partly funded by the Dutch Cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384bde611e7af191bfec5692d05cf021
https://doi.org/10.1038/s41556-022-00932-w
https://doi.org/10.1038/s41556-022-00932-w
Autor:
Lindsey Van Haute, Emily O’Connor, Héctor Díaz-Maldonado, Benjamin Munro, Kiran Polavarapu, Daniella H. Hock, Gautham Arunachal, Alkyoni Athanasiou-Fragkouli, Mainak Bardhan, Magalie Barth, Dominique Bonneau, Nicola Brunetti-Pierri, Gerarda Cappuccio, Nikeisha J. Caruana, Natalia Dominik, Himanshu Goel, Guy Helman, Henry Houlden, Guy Lenaers, Karine Mention, David Murphy, Bevinahalli Nandeesh, Catarina Olimpio, Christopher A. Powell, Veeramani Preethish-Kumar, Vincent Procaccio, Rocio Rius, Pedro Rebelo-Guiomar, Cas Simons, Seena Vengalil, Maha S. Zaki, Alban Ziegler, David R. Thorburn, David A. Stroud, Reza Maroofian, John Christodoulou, Claes Gustafsson, Atchayaram Nalini, Hanns Lochmüller, Michal Minczuk, Rita Horvath
Funder: EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c2dc7e42ec43005037539b14834e6e
Autor:
Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J. Garringer, Ruben Vidal, Grace I. Hallinan, Kathy L. Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gabor G. Kovacs, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G. Murzin, Michel Goedert, Sjors H. W. Scheres
Publikováno v:
Nature, 605(7909), 310-314. Nature Publishing Group
Many age-dependent neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, are characterized by abundant inclusions of amyloid filaments. Filamentous inclusions of the proteins tau, amyloid-β, α-synuclein and transactive response DNA-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ded8584e1f06a89d4adb15b9b46d57c
https://pure.eur.nl/en/publications/11fb046e-f3ec-4d89-b0e9-695ac325b3cc
https://pure.eur.nl/en/publications/11fb046e-f3ec-4d89-b0e9-695ac325b3cc
Autor:
McQuillan, H James, Clarkson, Jenny, Kauff, Alexia, Han, Su Young, Yip, Siew Hoong, Cheong, Isaiah, Porteous, Robert, Heather, Alison K, Herbison, Allan E
The mechanisms underlying the homeostatic estrogen negative feedback pathway central to mammalian fertility have remained unresolved. Direct measurement of gonadotropin-releasing hormone (GnRH) pulse generator activity in freely behaving mice with GC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fd2e677550524e4fb6f8a923cab320
Autor:
Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S. H. Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R. Zecchini, Sabrina H. Rossi, Charlie Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent Gnanapragasam, Anne Y. Warren, Grant D. Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza
Publikováno v:
Sciacovelli, M, Dugourd, A, Jiminez, L V, Yang, M, Nikitopoulou, E, Costa, A S H, Tronci, L, Caraffini, V, Rodrigues, P, Schmidt, C, Ryan, D, Young, T, Zicchini, V R, Rossi, S H, Massie, C, Lohoff, C, Masid, M, Hatzimanikatis, V, Kuppe, C, von Kriegsheim, A, Kramann, R, Gnanapragasam, V J, Warren, A Y, Stewart, G, Erez, A, Vanharanta, S, Saez-Rodriguez, J & Frezza, C 2022, ' Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression ', Nature Communications . https://doi.org/10.1038/s41467-022-35036-4
Nature Communications, 13(1):7830. Nature Publishing Group
Nature Communications 13(1), 7830 (2022). doi:10.1038/s41467-022-35036-4
Nature Communications, 13(1):7830. Nature Publishing Group
Nature Communications 13(1), 7830 (2022). doi:10.1038/s41467-022-35036-4
Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and metastatic clonally-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08279ff7c405b8dc36d9ce9cc4afaab
http://hdl.handle.net/10138/355207
http://hdl.handle.net/10138/355207
Autor:
Timothy M. Moore, Lijing Cheng, Dane M. Wolf, Jennifer Ngo, Mayuko Segawa, Xiaopeng Zhu, Alexander R. Strumwasser, Yang Cao, Bethan L. Clifford, Alice Ma, Philip Scumpia, Orian S. Shirihai, Thomas Q. de Aguiar Vallim, Markku Laakso, Aldons J. Lusis, Andrea L. Hevener, Zhenqi Zhou
Publikováno v:
Nature communications, vol 13, iss 1
Funder: UCLA Intercampus Medical Genetics Training Program (T32GM008243), NRSA predoctoral fellowship (F31DK108657), Carl V. Gisolfi Memorial Research grant from the American College of Sports Medicine, and a predoctoral graduate student award from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3ebae09621fea66c235cca9888ce18
https://doi.org/10.1038/s41467-022-34468-2
https://doi.org/10.1038/s41467-022-34468-2
Autor:
Mangolini, Maurizio, Maiques-Diaz, Alba, Charalampopoulou, Stella, Gerhard-Hartmann, Elena, Bloehdorn, Johannes, Moore, Andrew, Giachetti, Giorgia, Lu, Junyan, Roamio Franklin, Valar Nila, Chilamakuri, Chandra Sekkar Reddy, Moutsopoulos, Ilias, Rosenwald, Andreas, Stilgenbauer, Stephan, Zenz, Thorsten, Mohorianu, Irina, D'Santos, Clive, Deaglio, Silvia, Hodson, Daniel J, Martin-Subero, Jose I, Ringshausen, Ingo
Hotspot mutations in the PEST-domain of NOTCH1 and NOTCH2 are recurrently identified in B cell malignancies. To address how NOTCH-mutations contribute to a dismal prognosis, we have generated isogenic primary human tumor cells from patients with Chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11899aea8fad9f4ca973b6120f75a29
Publikováno v:
Nature Communications, 13
MicroRNAs (miRNAs) modulate physiological responses by repressing the expression of gene networks. We found that global deletion of microRNA-7 (miR-7), the most enriched miRNA in the hypothalamus, causes obesity in mice. Targeted deletion of miR-7 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc6f25cf8c49cca849549d6f21cbfc6
https://www.repository.cam.ac.uk/handle/1810/341547
https://www.repository.cam.ac.uk/handle/1810/341547
Autor:
Rai, Shivam, Grockowiak, Elodie, Hansen, Nils, Luque Paz, Damien, Stoll, Cedric B, Hao-Shen, Hui, Mild-Schneider, Gabriele, Dirnhofer, Stefan, Farady, Christopher J, Méndez-Ferrer, Simón, Skoda, Radek C
Interleukin-1β (IL-1β) is a master regulator of inflammation. Increased activity of IL-1β has been implicated in various pathological conditions including myeloproliferative neoplasms (MPNs). Here we show that IL-1β serum levels and expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a2b22bf39b9c82c3e92acd50018096
https://www.repository.cam.ac.uk/handle/1810/341003
https://www.repository.cam.ac.uk/handle/1810/341003
Autor:
Clement, M, Forbester, JL, Marsden, M, Sabberwal, P, Sommerville, MS, Wellington, D, Dimonte, S, Clare, S, Harcourt, K, Yin, Z, Nobre, L, Antrobus, R, Jin, B, Chen, M, Makvandi-Nejad, S, Lindborg, JA, Strittmatter, SM, Weekes, MP, Stanton, RJ, Dong, T, Humphreys, IR
Publikováno v:
Nature Communications. 13
Interferon-induced transmembrane protein 3 (IFITM3) is a restriction factor that limits viral pathogenesis and exerts poorly understood immunoregulatory functions. Here, using human and mouse models, we demonstrate that IFITM3 promotes MyD88-dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6894078c1439ff835f4fcc2c2ee842fc
https://doi.org/10.1038/s41467-022-32587-4
https://doi.org/10.1038/s41467-022-32587-4