Zobrazeno 1 - 10
of 141
pro vyhledávání: '"101/28"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J. Garringer, Ruben Vidal, Grace I. Hallinan, Kathy L. Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gabor G. Kovacs, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G. Murzin, Michel Goedert, Sjors H. W. Scheres
Publikováno v:
Nature, 605(7909), 310-314. Nature Publishing Group
Many age-dependent neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, are characterized by abundant inclusions of amyloid filaments. Filamentous inclusions of the proteins tau, amyloid-β, α-synuclein and transactive response DNA-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ded8584e1f06a89d4adb15b9b46d57c
https://pure.eur.nl/en/publications/11fb046e-f3ec-4d89-b0e9-695ac325b3cc
https://pure.eur.nl/en/publications/11fb046e-f3ec-4d89-b0e9-695ac325b3cc
Publikováno v:
Nature. 603:743-748
The fungal class D1 G-protein-coupled receptor (GPCR) Ste2 has a different arrangement of transmembrane helices compared with mammalian GPCRs and a distinct mode of coupling to the heterotrimeric G protein Gpa1–Ste2–Ste181. In addition, Ste2 lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a00b52c83b6da6a0f3f5846c3d80fe
https://doi.org/10.1038/s41586-022-04498-3
https://doi.org/10.1038/s41586-022-04498-3
Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2
Autor:
Kuan-Ying A. Huang, Xiaorui Chen, Arpita Mohapatra, Hong Thuy Vy Nguyen, Lisa Schimanski, Tiong Kit Tan, Pramila Rijal, Susan K. Vester, Rory A. Hills, Mark Howarth, Jennifer R. Keeffe, Alexander A. Cohen, Leesa M. Kakutani, Yi-Min Wu, Md Shahed-Al-Mahmud, Yu-Chi Chou, Pamela J. Bjorkman, Alain R. Townsend, Che Ma
Antibody-mediated immunity plays a crucial role in protection against SARS-CoV-2 infection. We isolated a panel of neutralizing anti-receptor-binding domain (RBD) antibodies elicited upon natural infection and vaccination and showed that they recogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a192fe78e6d7c16f5bbabcac7481c3
Autor:
Stephens, Amberley D, Villegas, Ana Fernandez, Chung, Chyi Wei, Vanderpoorten, Oliver, Pinotsi, Dorothea, Mela, Ioanna, Ward, Edward, McCoy, Thomas M, Cubitt, Robert, Routh, Alexander F, Kaminski, Clemens F, Kaminski Schierle, Gabriele S
Publikováno v:
Communications Biology, 6
Monomeric alpha-synuclein (aSyn) is a well characterised protein that importantly binds to lipids. aSyn monomers assemble into amyloid fibrils which are localised to lipids and organelles in insoluble structures found in Parkinson's disease patient's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baa7f119b85759d35dccc34ca72fcad
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, 12 (1)
Nature Communications
Nature Communications, 12 (1)
Nature Communications
Our innate immune responses to viral RNA are vital defenses. Long cytosolic double-stranded RNA (dsRNA) is recognized by MDA5. The ATPase activity of MDA5 contributes to its dsRNA binding selectivity. Mutations that reduce RNA selectivity can cause a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be0473d4f75a5612346c5478f88ed7f
https://doaj.org/article/4ed51115fdf7407f8d5ba6033a51c511
https://doaj.org/article/4ed51115fdf7407f8d5ba6033a51c511
Autor:
Nejc Kejzar, Elina Laanto, Ilona Rissanen, Vahid Abrishami, Muniyandi Selvaraj, Sylvain Moineau, Janne Ravantti, Lotta-Riina Sundberg, Juha T. Huiskonen
The origin of viruses remains an open question. While lack of detectable sequence similarity hampers the analysis of distantly related viruses, structural biology investigations of conserved capsid protein structures facilitate the study of distant e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b7e34a0bc0a832805b8698253da5b5
Autor:
Jan Böhning, Mnar Ghrayeb, Conrado Pedebos, Daniel K. Abbas, Syma Khalid, Liraz Chai, Tanmay A. M. Bharat
Many bacteria in nature exist in multicellular communities termed biofilms, where cells are embedded in an extracellular matrix that provides rigidity to the biofilm and protects cells from chemical and mechanical stresses. In the Gram-positive model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae94cd0ad40ef069d0eb60f8ed9c9381
https://www.repository.cam.ac.uk/handle/1810/344554
https://www.repository.cam.ac.uk/handle/1810/344554