Zobrazeno 1 - 10
of 94
pro vyhledávání: '"10024 Center for Microscopy and Image Analysis"'
The kidney is a structurally and functionally complex organ responsible for the control of water, ion, and other solute homeostasis. Moreover, the kidneys excrete metabolic waste products and produce hormones, such as renin and erythropoietin. The fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c45aca0fd5502aa960016e2f3b99b0
https://doi.org/10.5167/uzh-222736
https://doi.org/10.5167/uzh-222736
Autor:
Polesel, Marcello, Kaminska, Monika, Haenni, Dominik, Bugarski, Milica, Schuh, Claus, Jankovic, Nevena, Kaech, Andres, Mateos, Jose M, Berquez, Marine, Hall, Andrew M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dca6a7f46a328d6d2050b159d5e8bbe
https://www.zora.uzh.ch/id/eprint/222786/
https://www.zora.uzh.ch/id/eprint/222786/
Publikováno v:
J Am Soc Nephrol
BACKGROUND: The kidney plays an important role in maintaining normal blood pH. Metabolic acidosis (MA) upregulates the pathway that mitochondria in the proximal tubule (PT) use to produce ammonia and bicarbonate from glutamine, and is associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e5489349120ba488ea12d2a262f9ba
https://doi.org/10.1681/asn.2020071003
https://doi.org/10.1681/asn.2020071003
Autor:
Dominik Haenni, Marcello Polesel, Joana Raquel Martins, Claus Schuh, Andrew M. Hall, Milica Bugarski
The development of intravital imaging with multiphoton microscopy has had a major impact on kidney research. It provides the unique opportunity to visualize dynamic behavior of cells and organelles in their native environment and to relate this to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c52668788d2443f28790953e5bd4a3
https://doi.org/10.5167/uzh-204373
https://doi.org/10.5167/uzh-204373
Autor:
Ghazi, Susan, Bourgeois, Soline, Gomariz, Alvaro, Bugarski, Milica, Haenni, Dominik, Martins, Joana R, Nombela-Arrieta, César, Unwin, Robert J, Wagner, Carsten A, Hall, Andrew M, Craigie, Eilidh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______885::149a034879330ee514fde8464aa7496f
https://doi.org/10.5167/uzh-187880
https://doi.org/10.5167/uzh-187880
Autor:
Anne Kristine Meinild Lundby, Urs Ziegler, Petra S. Dittrich, Susan Ghazi, Claus-Dieter Schuh, Andrew M. Hall, Adam Pearson, Michael Duss, Milica Bugarski, Esther M. Gottwald, Patrick Drücker, Marcello Polesel, Ehud M. Landau, Carsten Lundby, Andres Kaech, Dominik Haenni
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports, 10 (1)
Scientific Reports
Scientific Reports, 10 (1)
The iron chelator Deferasirox (DFX) causes severe toxicity in patients for reasons that were previously unexplained. Here, using the kidney as a clinically relevant in vivo model for toxicity together with a broad range of experimental techniques, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83be6af9de3d8fe53dfdabe3b6f53496
https://doi.org/10.5167/uzh-183367
https://doi.org/10.5167/uzh-183367
Autor:
Natsuko Tokonami, Susan Ghazi, Alkaly Gassama, Evgenia Platonova, Marcello Polesel, Urs Ziegler, Andrew M. Hall, Milica Bugarski, Olivier Devuyst, Claus-Dieter Schuh, Dominik Haenni
Publikováno v:
Journal of the American Society of Nephrology. 29:2696-2712
Background The kidney proximal convoluted tubule (PCT) reabsorbs filtered macromolecules via receptor-mediated endocytosis (RME) or nonspecific fluid phase endocytosis (FPE); endocytosis is also an entry route for disease-causing toxins. PCT cells ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4195725dac85857c2787b00d272f45
https://doi.org/10.1681/asn.2018050522
https://doi.org/10.1681/asn.2018050522
Autor:
Ehud M. Landau, Claus-Dieter Schuh, Jenny A. Prange, Olivier Devuyst, Raffaele Mezzenga, Marek Komisarski, Andrew M. Hall, Alessandro Luciani, Simone Aleandri, Andres Käch
The use of lipid-based nanoparticles for the delivery of biomacromolecules has attracted considerable attention due to the current interest in protein-based therapeutics. Cubosomes protect the incorporated therapeutics, which are susceptible to degra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7887790f409117b540090737afb7068c
https://doi.org/10.5167/uzh-179839
https://doi.org/10.5167/uzh-179839
Autor:
Mathias Ackermann, Andres Kaech, Anna Paula de Oliveira, Cornel Fraevel, Elisabeth M. Schraner, Sabine Leisinger, Jana Doehner, Peter J. Wild
Publikováno v:
F1000Research
Background: Capsids of herpes simplex virus 1 (HSV-1) are assembled in the nucleus, translocated either to the perinuclear space by budding at the inner nuclear membrane acquiring tegument and envelope, or released to the cytosol in a “naked” sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae894369521185c0023689426732bac8
http://europepmc.org/articles/PMC6584977
http://europepmc.org/articles/PMC6584977