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Hydrophobic natural deep eutectic-solvent bar microextraction combined with HPLC-DAD for determination of urinary 1-hydroxypyrene of smokers

Autor: Nabil N. AL-Hashimi, Husam Abed Alfattah, Amjad H. El-Sheikh, Jafar I. Abdelghani, Abdelrahim M.A. Alqudah, Alaa S. Alfawaz

Publikováno v: Emerging Contaminants, Vol 9, Iss 4, Pp 100250- (2023)

1-hydroxypyrene (1-OHP) is a metabolite of pyrene, which is a type of polycyclic aromatic hydrocarbons (PAHs) found in tobacco smoke and preferred use as a biomarker to determine exposure to PAHs from smoking. This paper reports a new and simple micr

Externí odkaz: https://doaj.org/article/5f19cd0edf6445469aa7253ca6c58e58

1‐Hydroxypyrene mediates renal fibrosis through aryl hydrocarbon receptor signalling pathway.

Autor: Miao, Hua¹ (AUTHOR), Wu, Xia‐Qing¹ (AUTHOR), Wang, Yan‐Ni¹ (AUTHOR), Chen, Dan‐Qian¹ (AUTHOR), Chen, Lin¹ (AUTHOR), Vaziri, Nosratola D.² (AUTHOR), Zhuang, Shougang^3,4 (AUTHOR), Guo, Yan⁵ (AUTHOR), Su, Wei⁶ (AUTHOR), Ma, Shi‐Xing⁶ (AUTHOR), Zhang, Huan‐Qiao⁶ (AUTHOR), Shang, You‐Quan⁶ (AUTHOR), Yu, Xiao‐Yong⁷ (AUTHOR), Zhao, Yan‐Long⁷ (AUTHOR), Mao, Jia‐Rong⁷ (AUTHOR), Gao, Ming⁸ (AUTHOR), Zhang, Jin‐Hua⁸ (AUTHOR), Zhao, Jin⁸ (AUTHOR), Zhang, Yuan⁸ (AUTHOR), Zhang, Li⁸ (AUTHOR)

Publikováno v: British Journal of Pharmacology. Jan2022, Vol. 179 Issue 1, p103-124. 22p. 8 Graphs.

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Identification and characterization of 1-hydroxypyrene contents in urine as a marker of exposure to pah in workers of electrolysis workshops at aluminum production

Autor: S.F. Shayakhmetov, A.N. Alekseenko, A.V. Merinov, O.M. Zhurba

Publikováno v: Analiz Riska Zdorovʹû, Iss 3, Pp 90-97 (2022)

Potential harmful effects produced by highly toxic aromatic hydrocarbons (PAH) on health of workers employed at aluminum production make it necessary to identify biomarkers of exposure to the toxicants and to assess health risks. Our research goal

Externí odkaz: https://doaj.org/article/c69933b44ebd4c8baf5ea3c41e386223