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Hydrogen sulfide mitigates skeletal muscle mitophagy‐led tissue remodeling via epigenetic regulation of the gene writer and eraser function

Autor: Mahavir Singh, Sathnur Pushpakumar, Yuting Zheng, Rubens P. Homme, Irina Smolenkova, Sri Prakash L. Mokshagundam, Suresh C. Tyagi

Publikováno v: Physiological Reports, Vol 10, Iss 16, Pp n/a-n/a (2022)

Abstract Ketone bodies (KB) serve as the food for mitochondrial biogenetics. Interestingly, probiotics are known to promote KB formation in the gut (especially those that belong to the Lactobacillus genus). Furthermore, Lactobacillus helps produce fo

Externí odkaz: https://doaj.org/article/fe138af1462448f78b23570c045ce853

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Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic Analysis

Autor: Anna Shcherbina, Jacqueline Larouche, Paula Fraczek, Benjamin A. Yang, Lemuel A. Brown, James F. Markworth, Carolina H. Chung, Mehwish Khaliq, Kanishka de Silva, Jeongmoon J. Choi, Mohammad Fallahi-Sichani, Sriram Chandrasekaran, Young C. Jang, Susan V. Brooks, Carlos A. Aguilar

Publikováno v: Cell Reports, Vol 32, Iss 4, Pp 107964- (2020)

Summary: During aging, there is a progressive loss of volume and function in skeletal muscle that impacts mobility and quality of life. The repair of skeletal muscle is regulated by tissue-resident stem cells called satellite cells (or muscle stem ce

Externí odkaz: https://doaj.org/article/4c25cc2531574597b3eba84ef930cfd5

Cardiovascular manifestations of intermediate and major hyperhomocysteinemia due to vitamin B12 and folate deficiency and/or inherited disorders of one-carbon metabolism: a 3.5-year retrospective cross-sectional study of consecutive patients

Autor: Elise Jeannesson, Julien Levy, Stéphane Ziuly, Rosa-Maria Rodriguez-Guéant, Jean-Louis Guéant, Abderrahim Oussalah, Denis Wahl

Publikováno v: American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, American Society for Nutrition, 2021, 113 (5), pp.1157-1167. ⟨10.1093/ajcn/nqaa432⟩

International audience; ABSTRACT Background The association of moderate hyperhomocysteinemia (HHcy) (15–30 μmol/L) with cardiovascular diseases (CVD) has been challenged by the lack of benefit of vitamin supplementation to lowering homocysteine. C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4566f889eedf0a64e0972cf4adb769b
https://doi.org/10.1093/ajcn/nqaa432