1,25(OH)2D3 deficiency-induced gut microbial dysbiosis degrades the colonic mucus barrier in Cyp27b1 knockout mouse model

Autor: Wenjing Zhu, Jiayao Yan, Chunchun Zhi, Qianwen Zhou, Xiaoqin Yuan

Publikováno v: Gut Pathogens, Vol 11, Iss 1, Pp 1-11 (2019)

Abstract Background The relationship between disturbances of the gut microbiota and 1,25(OH)2D3 deficiency has been established both in humans and animal models with a vitamin D poor diet or a lack of sun exposure. Our prior study has demonstrated th

Externí odkaz: https://doaj.org/article/f42fabac3ebe4d999a84f85688f8d6f4

1,25(OH) 2 D 3 deficiency-induced gut microbial dysbiosis degrades the colonic mucus barrier in Cyp27b1 knockout mouse model.

Autor: Zhu W; 1Department of Anatomy, Histology and Embryology, Nanjing Medical University, Xuehai Building, Rm D509, 101 Longmian Avenue, Jiangning District, Nanjing, 211166 China., Yan J; 2Department of Clinical Medicine, First Clinical Medicine College, Nanjing Medical University, Nanjing, 211166 China., Zhi C; 4Department of Pathology, Nanjing Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210002 China., Zhou Q; 1Department of Anatomy, Histology and Embryology, Nanjing Medical University, Xuehai Building, Rm D509, 101 Longmian Avenue, Jiangning District, Nanjing, 211166 China., Yuan X; 1Department of Anatomy, Histology and Embryology, Nanjing Medical University, Xuehai Building, Rm D509, 101 Longmian Avenue, Jiangning District, Nanjing, 211166 China.; 3Key Laboratory for Aging & Disease, Nanjing Medical University, Nanjing, 211166 China.

Publikováno v: Gut pathogens [Gut Pathog] 2019 Feb 20; Vol. 11, pp. 8. Date of Electronic Publication: 2019 Feb 20 (Print Publication: 2019).