Zobrazeno 1 - 10
of 42
pro vyhledávání: '"0604 Genetics, 1103 Clinical Sciences"'
Publikováno v:
Genetics in Medicine. 24:2144-2154
PURPOSE: There is significant interest in the use of polygenic risk score (PRS) tests to improve cancer risk assessment and stratified prevention. Our current understanding of preferences regarding different aspects of this novel testing approach is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396c4755c1ff76bc9b55c5499622f341
https://doi.org/10.1016/j.gim.2022.07.011
https://doi.org/10.1016/j.gim.2022.07.011
Publikováno v:
European Journal of Human Genetics. 30:756-765
There is currently no consensus on the key outcomes of reproductive genetic carrier screening (RGCS). This has led to a large amount of variability in approaches to research, limiting direct comparison and synthesis of findings. In a recently publish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecceae82503f138c7028e0b0e966e45d
https://doi.org/10.1038/s41431-022-01090-1
https://doi.org/10.1038/s41431-022-01090-1
Publikováno v:
Genetics in Medicine. 24:1-14
Purpose: Current practice recommendations support the widespread implementation of reproductive genetic carrier screening (RGCS). These consensus-based recommendations highlight a research gap, with findings from current studies being insufficient to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88063f2cf5f3303cf84a37554b19c87
https://doi.org/10.1016/j.gim.2021.08.005
https://doi.org/10.1016/j.gim.2021.08.005
Autor:
Erin Turbitt, Jennefer N. Kohler, Frank Angelo, Ilana M. Miller, Katie L. Lewis, Katrina A.B. Goddard, Benjamin S. Wilfond, Barbara B. Biesecker, Michael C. Leo
PURPOSE: People report experiencing value from learning genomic results even in the absence of clinically actionable information. Such personal utility has emerged as a key concept in genomic medicine. The lack of a validated patient-reported outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17abbf070a4bd6c824643df0723668e9
https://hdl.handle.net/10453/166278
https://hdl.handle.net/10453/166278
Autor:
Bronwyn Terrill, Mary-Anne Young, Mandy L. Ballinger, Alison McEwen, Amanda M. Willis, Angela Pearce
Publikováno v:
Eur J Hum Genet
Researchers and research participants increasingly support returning clinically actionable genetic research findings to participants, but researchers may lack the skills and resources to do so. In response, a genetic counsellor-led program to facilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeac01199bb95f9c663247300d328f94
https://doi.org/10.1038/s41431-021-00973-z
https://doi.org/10.1038/s41431-021-00973-z
Autor:
Amelia L. Parker, Elise Bowman, Adriana Zingone, Brid M. Ryan, Wendy A. Cooper, Maija Kohonen-Corish, Curtis C. Harris, Thomas R. Cox
Publikováno v:
Genome Medicine. 14
Background Squamous cell carcinoma (SqCC) is a subtype of non-small cell lung cancer for which patient prognosis remains poor. The extracellular matrix (ECM) is critical in regulating cell behavior; however, its importance in tumor aggressiveness rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd80624d061c8fec006620c431e120f
https://doi.org/10.1186/s13073-022-01127-6
https://doi.org/10.1186/s13073-022-01127-6
Autor:
Clare A. Primiero, Amy M. Baker, Courtney K. Wallingford, Ellie J. Maas, Tatiane Yanes, Lindsay Fowles, Monika Janda, Mary-Anne Young, Amy Nisselle, Bronwyn Terrill, Jason M. Lodge, Jane M. Tiller, Paul Lacaze, Hayley Andersen, Gemma McErlean, Erin Turbitt, H. Peter Soyer, Aideen M. McInerney-Leo
Publikováno v:
Frontiers in Genetics. 13
Background:Melanoma genetic testing reportedly increases preventative behaviour without causing psychological harm. Genetic testing for familial melanoma risk is now available, yet little is known about dermatologists’ perceptions regarding the uti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1451713fb0c8498b31c329f4a26062b
https://doi.org/10.3389/fgene.2022.919134
https://doi.org/10.3389/fgene.2022.919134
Autor:
Roya, Ramezankhani, Afshin Abdi, Ghavidel, Saadyeh, Rashidi, Mahbubeh, Rojhannezhad, Hamid Reza, Abolkheir, Malihe, Mirhosseini, Sara, Taleahmad, Massoud, Vosough
Pancreatic cancer (PC) is one of the leading causes of cancer mortality worldwide, and its incidence and mortality rate in several regions is higher in male patients. Although numerous efforts have been made to enhance the clinical outcomes of existi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e20333840ec4420042591e9d967b03
https://hdl.handle.net/10453/169990
https://hdl.handle.net/10453/169990
Autor:
Caitlin G. Allen, Alison E. Fohner, Megan C. Roberts, Amelia K Smit, Dana Lee Olstad, Latrice Landry, Erin Turbitt
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-10 (2021)
Genome Medicine
Genome Medicine
Precision public health is a relatively new field that integrates components of precision medicine, such as human genomics research, with public health concepts to help improve population health. Despite interest in advancing precision public health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e580dc81b69d5e4aa663bb6aa69cff7
https://doaj.org/article/fd1812512ef344c19ec0020b1f1f55ee
https://doaj.org/article/fd1812512ef344c19ec0020b1f1f55ee
Genetic information can provide clinical benefits to families of palliative patients. However, integration of genetics into mainstream medicine has not focused on palliative populations. We explored the views and experiences of genetic health profess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcf41aae5d42bc74ce56bdf5a741857
https://hdl.handle.net/10453/163927
https://hdl.handle.net/10453/163927