Zobrazeno 1 - 10
of 10
pro vyhledávání: '"060114 Systems Biology"'
Publikováno v:
Journal of the Royal Society Interface
Stochasticity is a key characteristic of intracellular processes such as gene regulation and chemical signalling. Therefore, characterizing stochastic effects in biochemical systems is essential to understand the complex dynamics of living things. Ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b47eacfc83174b66664360036385cc
https://europepmc.org/articles/PMC6408336/
https://europepmc.org/articles/PMC6408336/
Autor:
Dimitri Perrin, Guido Zuccon
Publikováno v:
F1000Research
Biological networks are highly modular and contain a large number of clusters, which are often associated with a specific biological function or disease. Identifying these clusters, or modules, is therefore valuable, but it is not trivial. In this ar
Autor:
Dee A. Carter, Simone S. Li, Leona T. Campbell, Ben Herbert, Matthew P. Padula, Hin Siong Chong, Cameron J. Hill, Marc R. Wilkins, Elizabeth J. Harry
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e42835 (2012)
PLoS ONE, Vol 7, Iss 8, p e42835 (2012)
Cryptococcus gattii is an encapsulated fungus capable of causing fatal disease in immunocompetent humans and animals. As current antifungal therapies are few and limited in efficacy, and resistance is an emerging issue, the development of new treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78eed0bfb0682b9e8acf10b71ca8e2b
https://hdl.handle.net/2123/10102
https://hdl.handle.net/2123/10102
Publikováno v:
BMC Systems Biology, Vol 5, Iss 1, p 35 (2011)
BMC Systems Biology
BMC Systems Biology
Background Cancer has remarkable complexity at the molecular level, with multiple genes, proteins, pathways and regulatory interconnections being affected. We introduce a systems biology approach to study cancer that formally integrates the available
Autor:
Netzel-Anett, Sarah, Bugge, Thomas, Hess, Rex, Carnes, Kay, Stringer, Brett, Scarman, Anthony, Hooper, John, Tonks, Ian, Kay, Graham, Antalis, Toni
Publikováno v:
Biology of Reproduction
Publikováno v:
Computational Models For Life Sciences (CMLS '07): Proceedings of International Symposium on Computational Models for Life Sciences
Recently, an analysis of the response curve of the vascular endothelial growth factor (VEGF) receptor and its application to cancer therapy was described in [T. Alarcón, and K. Page, J. R. Soc. Lond. Interface 4, 283–304 (2007)]. The analysis is s
Publikováno v:
Positive Systems ISBN: 9783540347712
Lecture Notes in Control and Information Science: The Second Multidisciplinary International Symposium on Positive Systems : Theory and Applications (POSTA 06)
Monash University
Lecture Notes in Control and Information Science: The Second Multidisciplinary International Symposium on Positive Systems : Theory and Applications (POSTA 06)
Monash University
Biologists are increasingly conscious of the critical role that noise plays in cellular functions such as genetic regulation, often in connection with fluctuations in small numbers of key regulatory molecules. This has inspired the development of mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fe21b132d8dbe9094054200cdd2d05
https://doi.org/10.1007/3-540-34774-7_46
https://doi.org/10.1007/3-540-34774-7_46
Autor:
H. C. Harsha, G. Hanumanthu, Salil Sharma, H N Shivashankar, Raghunath Reddy, Tejal K. Gandhi, Krishna S. Deshpande, Vidya Niranjan, K. S. Arun, S. Reshma, D. Julie, K. S. Mangala, Malabika Sarker, Sreenath Chandran, M. Suresh, P. Chatterjee, L. Karthick, Babylakshmi Muthusamy, Anuradha Nalli, Akhilesh Pandey, Nandan P. Deshpande, Madhu Mahesh, S. Lynate John, G. Vishnupriya, Shubha Suresh, K N Chandrika, Trafina Jadhav, Raghothama Chaerkady, T. S. Keshava Prasad, P. Bala, B. M. Vrushabendra, Kaushik Dhar, Subburaman Mohan, D. Sudhir, D. Srinivas, Kshitish Palvankar, Goparani Mishra, B. Rekha, N. Kannabiran, N. S. Rashmi
Publikováno v:
Proteomics
Plasma is one of the best studied compartments in the human body and serves as an ideal body fluid for the diagnosis of diseases. This report provides a detailed functional annotation of all the plasma proteins identified to date. In all, gene produc
Autor:
Robert J. Matusik, Colleen C. Nelson, Yajun Yi, Tatjana Radmilovic, Thomas C. Case, Karen D. Tsuchiya, Srinivas Nandana
Publikováno v:
Molecular Cytogenetics
Molecular Cytogenetics, Vol 2, Iss 1, p 18 (2009)
Molecular Cytogenetics, Vol 2, Iss 1, p 18 (2009)
Background The purpose of this study was to identify candidate metastasis suppressor genes from a mouse allograft model of prostate cancer (NE-10). This allograft model originally developed metastases by twelve weeks after implantation in male athymi
Publikováno v:
Trends in Biochemical Sciences
article free to read on journal website Although the signaling pathways downstream of receptors such as cytokine receptors are quite well understood, the exact mechanisms employed by many other transmembrane proteins are yet to be fully elucidated. A