Zobrazeno 1 - 10
of 49
pro vyhledávání: '"0601 Biochemistry and Cell Biology, 1115 Pharmacology and Pharmaceutical Sciences"'
Autor:
Jesus Shrestha, Keshav Raj Paudel, Hojjatollah Nazari, Vivek Dharwal, Sajad Razavi Bazaz, Matt D. Johansen, Kamal Dua, Philip M. Hansbro, Majid Ebrahimi Warkiani
Publikováno v:
Medicinal Research Reviews.
The global burden of respiratory diseases is enormous, with many millions of people suffering and dying prematurely every year. The global COVID-19 pandemic witnessed recently, along with increased air pollution and wildfire events, increases the urg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265570c77220d1f636885e5cfdbe0d8b
https://doi.org/10.1002/med.21956
https://doi.org/10.1002/med.21956
Autor:
Jaskiran, Kaur, Monica, Gulati, Niraj Kumar, Jha, John, Disouza, Vandana, Patravale, Kamal, Dua, Sachin Kumar, Singh
Publikováno v:
Drug Discovery Today. 27:1495-1512
Polymeric micelles (PMs) have been explored pre-clinically for the delivery of chemotherapeutics to treat cancer. Their unique features, such as easy surface functionalization, stimuli-responsiveness, good stability, ability to modify drug release, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c806e71b49ef75ca0181b8cc8291f620
https://doi.org/10.1016/j.drudis.2022.02.005
https://doi.org/10.1016/j.drudis.2022.02.005
Publikováno v:
Drug Testing and Analysis. 14:983-990
The concept of biomarker measurements in the form of a ratio has not been explored in detail. This is surprising considering the current and future potential for biomarkers incorporating endogenous reference compounds (ERCs) in a range of fields. A s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1707a7c24f9ba968ad55d1ed217e3b8e
https://doi.org/10.1002/dta.3250
https://doi.org/10.1002/dta.3250
Autor:
Petur Dalsgaard, Daniel Pasin, Meiru Pan, Brian Schou Rasmussen, Kristian Linnet, Christian Brinch Mollerup
Publikováno v:
Pasin, D J, Pan, M, Rasmussen, B S, Linnet, K, Dalsgaard, P W & Mollerup, C B 2022, ' Metabolomics-driven determination of targets for salicylic acid and ibuprofen in positive electrospray ionization using LC-HRMS ', Drug Testing and Analysis, vol. 14, no. 4, pp. 747-756 . https://doi.org/10.1002/dta.3215
Due to the large number of basic therapeutic and illicit drugs, systematic toxicological analysis has widely been performed with liquid chromatography coupled to mass spectrometry using positive electrospray ionization. However, there exist a smaller
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07efdf2dc21d11792ca9a6b6e01c0ebb
https://doi.org/10.1002/dta.3215
https://doi.org/10.1002/dta.3215
Aging is one of the major risk factors for most neurodegenerative disorders including Parkinson's disease (PD). More than 10 million people are affected with PD worldwide. One of the predominant factors accountable for progression of PD pathology cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e15ce5170ace84ffe37904785d75ed31
https://hdl.handle.net/10453/170137
https://hdl.handle.net/10453/170137
Autor:
Alharbi, KS, Javed Shaikh, MA, Imam, SS, Alshehri, S, Ghoneim, MM, Almalki, WH, Singh, SK, Kumar, D, Kumar, AP, Dua, K, Chellappan, DK, Paudel, KR, Gupta, G
More than 10 million people worldwide have Alzheimer's disease (AD), a degenerative neurological illness and the most prevalent form of dementia. AD's progression in memory loss, cognitive deterioration, and behavioral changes are all symptoms. Amylo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::cdbd7bf8a1a7fcd4d083c9215b0c17f4
https://hdl.handle.net/10453/165114
https://hdl.handle.net/10453/165114
Publikováno v:
Journal of Chromatography B. 1220:123652
The use of catechol-O-methyltransferase inhibitors may mask doping agents, primarily levodopa, administered to racehorses and prolong the stimulating effects of dopaminergic compounds such as dopamine. It is known that 3-methoxytyramine is a metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ecfc4e31ec19604167988956a6f677
https://doi.org/10.1016/j.jchromb.2023.123652
https://doi.org/10.1016/j.jchromb.2023.123652
Autor:
Isabella Francis, Jesus Shrestha, Keshav Raj Paudel, Philip M. Hansbro, Majid Ebrahimi Warkiani, Suvash C. Saha
With the global burden of respiratory diseases, rapid identification of the best therapeutic measures to combat these diseases is essential. Animal models and 2D cell culture models do not replicate the findings observed in vivo. To gain deeper insig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b0b459717edc1d413a4319ba71552a
https://hdl.handle.net/10453/158239
https://hdl.handle.net/10453/158239
Publikováno v:
Drug Testing and Analysis. 13:990-1000
The constant evolution of the illicit drug market makes the identification of unknown compounds problematic. Obtaining certified reference materials for a broad array of new analogues can be difficult and cost prohibitive. Machine learning provides a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255aab92f52fc5505d8d20f12ca52dff
https://doi.org/10.1002/dta.2976
https://doi.org/10.1002/dta.2976