Zobrazeno 1 - 10
of 48 831
pro vyhledávání: '"-omics"'
Autor:
Wen Li, Zhining Zhang, Bo Xie, Yunlin He, Kangming He, Hong Qiu, Zhiwei Lu, Chunlan Jiang, Xuanyu Pan, Yuxiao He, Wenyu Hu, Wenjian Liu, Tengcheng Que, Yanling Hu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 659-668 (2024)
Analyzing the vast amount of omics data generated comprehensively by high-throughput sequencing technology is of utmost importance for scientists. In this context, we propose HiOmics, a cloud-based platform equipped with nearly 300 plugins designed f
Externí odkaz:
https://doaj.org/article/cc3d4f483fd84cf4ac82b8b3937ad17e
Autor:
William DeGroat, Habiba Abdelhalim, Elizabeth Peker, Neev Sheth, Rishabh Narayanan, Saman Zeeshan, Bruce T. Liang, Zeeshan Ahmed
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Cardiovascular diseases (CVDs) are complex, multifactorial conditions that require personalized assessment and treatment. Advancements in multi-omics technologies, namely RNA sequencing and whole-genome sequencing, have provided translationa
Externí odkaz:
https://doaj.org/article/b57cbcd9db094e298b7798240d408a22
Autor:
Xiaoting Zhu, Wubin Long, Jing Zhang, Congcong Jian, Jianghua Chen, Jiaxin Huang, Shilin Li, Jie Zhang, Liang Wang, Yan Chen, Jianhong Wu, Tingting Wang, Qinghua Zou, Jing Zhu, Fanxin Zeng
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Objectives Patients with rheumatoid arthritis (RA) commonly experience a high prevalence of multiple metabolic diseases (MD), leading to higher morbidity and premature mortality. Here, we aimed to investigate the pathogenesis of MD in RA pat
Externí odkaz:
https://doaj.org/article/95b718d7d78e4deabf236f3f6c92b549
Autor:
Sulong Wang, Xin Yang, Kai Liu, Debin Xiong, Ainizier Yalikun, Yimurang Hamiti, Aihemaitijiang Yusufu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Muscle atrophy caused by denervation is common in neuromuscular diseases, leading to loss of muscle mass and function. However, a comprehensive understanding of the overall molecular network changes during muscle denervation atrop
Externí odkaz:
https://doaj.org/article/20b3e31df8fc40ab8137871cc5cecb78
Autor:
Kaidi Guo, Twan van den Beucken
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Drug-induced liver injury (DILI) refers to drug-mediated damage to the structure and function of the liver, ranging from mild elevation of liver enzymes to severe hepatic insufficiency, and in some cases, progressing to liver failure. The me
Externí odkaz:
https://doaj.org/article/c120c6014f13434a9d28e66c1f362f61
Publikováno v:
BioData Mining, Vol 17, Iss 1, Pp 1-36 (2024)
Abstract Background High-dimensional omics data integration has emerged as a prominent avenue within the healthcare industry, presenting substantial potential to improve predictive models. However, the data integration process faces several challenge
Externí odkaz:
https://doaj.org/article/6782224d4d6e4c348559e330ec160841
Autor:
Zhenjiang Wang, Mingyi Guo, Sen Yang, Yuping Chen, Jianbin Cheng, Zaiwei Huang, Tongxu Wang, Xiaobei Luo, Xingxiang He, Dali Wang, Xiaohong Xu
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Specific intestinal metabolites are closely associated with the classification, severity, and necrosis of acute pancreatitis (AP) and provide novel insights for in-depth clinical investigations. In this study, the gut microbiota and metaboli
Externí odkaz:
https://doaj.org/article/5b979c29c87e4f6cb346471eb84d613e
Autor:
Fan Yang, Long-You Zhao, Wen-Qi Yang, Shan Chao, Zong-Xin Ling, Bo-Yao Sun, Li-Ping Wei, Li-Juan Zhang, Li-Mei Yu, Guang-Yong Cai
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Multiple sclerosis (MS) is an autoimmune disorder caused by chronic inflammatory reactions in the central nervous system. Currently, little is known about the changes of plasma proteomic profiles in Chinese patients with MS (CpwMS) and its r
Externí odkaz:
https://doaj.org/article/f80fd94812b14049b824072f4ac492c4
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Uterine sarcoma (US) is a rare malignant tumor that has various pathological types and high heterogeneity in the female reproductive system. Its subtle early symptoms, frequent recurrence, and resistance to radiation and chemotherapy make th
Externí odkaz:
https://doaj.org/article/e36a336511214308baa93c616ffcb8e7
Autor:
Aswin Thacharodi, Prabhakar Singh, Ramu Meenatchi, Z. H. Tawfeeq Ahmed, Rejith R. S. Kumar, Neha V, Sanjana Kavish, Mohsin Maqbool, Saqib Hassan
Publikováno v:
Health Care Science, Vol 3, Iss 5, Pp 329-349 (2024)
Abstract The increasing integration of new technologies is driving a fundamental revolution in the healthcare sector. Developments in artificial intelligence (AI), machine learning, and big data analytics have completely transformed the diagnosis, tr
Externí odkaz:
https://doaj.org/article/a658ff9bd9674f9b966f19c189af7142