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pro vyhledávání: '"潘晓光(Pan Xiaoguang)"'
Autor:
潘晓光(Pan Xiaoguang)
Extrachromosomal circular DNA is a newly evolved hallmark in cancer and is associated with cancer genome instability, oncogene amplification, acquired resistance, and disease progression. A Cancer Circular Genome Atlas (CCGA) consortium is formed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f0e0c5784d8b4c62a7905355071f71f
Autor:
潘晓光(Pan Xiaoguang)
Extrachromosomal circular DNAs (eccDNAs) are circular and mobile DNA molecules derived from linear chromosomes. They have been found in various tumor types. However, the genomic characterization and the potential role of eccDNAs in the carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d2a1c01b4859ace92fb5fb58b07c31c
Autor:
潘晓光(Pan Xiaoguang)
Extrachromosomal circular DNA (eccDNA) is evolving as a valuable biomarker while little is known about its presence in urine. Here we report the discovery and analysis of urinary cell free eccDNAs (ucf-eccDNA) in healthy controls and patients with ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4821bb3d1458046fb99fa93c4a9f0378
Autor:
潘晓光(Pan Xiaoguang)
A major challenge of CRISPR/Cas9-mediated genome engineering is that not all guide RNAs cleave DNA efficiently. Here, we show that local gRNA-DNA interactions resulting from Cas9 sliding on overlapping protospacer adjacent motifs profoundly impact gR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5a430a200177b1b3269ffe34e621589