Zobrazeno 1 - 10
of 35
pro vyhledávání: '"二甲双胍"'
Autor:
Leili Gao, Xingwu Ran, Xuejun Liu, Xingping Shen, Shuchun Chen, Fuqiang Liu, Dong Zhao, Yan Bi, Qing Su, Yao Lu, Minxiang Lei, Yanfang Wang, Linong Ji
Publikováno v:
Journal of Diabetes, Vol 15, Iss 9, Pp 765-776 (2023)
Abstract Aims To evaluate the prevalence of vitamin B12 deficiency in Chinese patients with type 2 diabetes mellitus receiving metformin treatment and to investigate the effects of metformin daily dose and treatment duration on the prevalence of vita
Externí odkaz:
https://doaj.org/article/068742a8a5794cf597617e3a69f2f461
Autor:
Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb, Athanasios Alexiou, Marios Papadakis, Eman Hassan Nadwa, Sarah M. Albogami, Mohammed Alorabi, Hebatallah M. Saad, Gaber El‐Saber Batiha
Publikováno v:
Journal of Diabetes, Vol 14, Iss 12, Pp 806-814 (2022)
Abstract Type 2 diabetes mellitus (T2DM) is a chronic endocrine disorder due to the reduction of insulin sensitivity and relative deficiency of insulin secretion. Growth differentiation factor 15 (GDF15) belongs to the transforming growth factor beta
Externí odkaz:
https://doaj.org/article/cb0faae2b681447ca78abf9c856e75ef
Publikováno v:
Zhongshan Daxue xuebao. Yixue kexue ban, Vol 43, Pp 905-915 (2022)
目的对比分析屋尘螨（HDM）诱导的过敏性哮喘小鼠模型26 d的急性模型和59 d的慢性模型，评价二甲双胍和孟鲁司特对气道炎症和气道重塑病理效应的改善作用。方法HDM致敏和激发构建急性和
Externí odkaz:
https://doaj.org/article/fa175371137b476eb220d17a57f9f99d
Publikováno v:
Journal of Diabetes, Vol 14, Iss 10, Pp 658-669 (2022)
Abstract Metformin is a hypoglycemic drug widely used in the treatment of type 2 diabetes. It has been proven to have analgesic and neuroprotective effects. Metformin can reverse pain in rodents, such as diabetic neuropathic pain, neuropathic pain ca
Externí odkaz:
https://doaj.org/article/e3ae031a8ae2405d856b15b032512825
Publikováno v:
Zhongshan Daxue xuebao. Yixue kexue ban, Vol 43, Pp 522-529 (2022)
目的探讨二甲双胍（Met）作用AD细胞模型M146L的淀粉样蛋白-β（Aβ）病理改善作用及其潜在机制。方法MTT比色法检测不同浓度Met对细胞活力的影响；Western Blotting检测Met处理后Aβ42、生成Aβ相关
Externí odkaz:
https://doaj.org/article/571ad52d4d734ae6981cd9ad262c8dc0
Autor:
张敏，李洪伟，隋长百，高越，赵咏梅，徐丽霞，孟霞
Publikováno v:
Zhongguo cuzhong zazhi, Vol 16, Iss 4, Pp 408-412 (2021)
Externí odkaz:
https://doaj.org/article/b418d63f58104ce8b899e6e9ef4ecd9d
Publikováno v:
Zhongshan Daxue xuebao. Yixue kexue ban, Vol 38 (2017)
【目的】观察二甲双胍对于肥胖儿童非酒精性脂肪性肝病（NAFLD）的治疗效果。【方法】回顾性分析2013年 7月10日至2016年8月23日中山大学附属第一医院儿科内分泌门诊诊断为NAFLD，伴ALT、AST
Externí odkaz:
https://doaj.org/article/002ddbc916c347bd94a13fd1119b8dd9
Autor:
黎洁洁，彭玉晶，王拥军
Publikováno v:
Zhongguo cuzhong zazhi, Vol 13, Iss 8, Pp 934-839 (2018)
目的 研究糖尿病前期对短暂局灶脑缺血后长期认知功能的影响，以及早期二甲双胍治疗的效果。 方法 给予6周龄的雄性Wistar大鼠高脂饮食构建糖尿病前期模型。糖尿病前期大鼠在10周龄时给
Externí odkaz:
https://doaj.org/article/d23b3db47ed84df082ccdb18d2cd9a0d
Publikováno v:
Zhongshan Daxue xuebao. Yixue kexue ban, Vol 35 (2014)
摘 要: 【目的】 探讨二甲双胍对多囊卵巢综合征(PCOS)大鼠胰岛素敏感性的作用及机制?【方法】 应用脱氢表雄酮制备PCOS大鼠模型20只,随机分为二甲双胍干预组?PCOS组各10只,同批大鼠设为正常
Externí odkaz:
https://doaj.org/article/c21fe5dd8a4546e7aba6dd846c7cb9d0
Publikováno v:
Zhongshan Daxue xuebao. Yixue kexue ban, Vol 27 (2006)
[目的]以逆转录（RT）和实时定量聚合酶链式反应（real-time qPCR）方法检测和分析非酒精性脂肪肝（NAFLD）大鼠模型的药物干预效果.[方法]以高脂饲料饲喂雄性Wistar大鼠12周诱发NAFLD,然后转以基
Externí odkaz:
https://doaj.org/article/3655c5f3e02f4a4096d1ca731b8252eb