Zobrazeno 1 - 10
of 81
pro vyhledávání: '"‡ and Amy-Joan L. Ham"'
Autor:
Sunil K. Halder, Yong-Jig Cho, Arunima Datta, Govindaraj Anumanthan, Amy-Joan L. Ham, David P. Carbone, Pran K. Datta
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 10, Pp 912-922 (2011)
Lung carcinogenesis in humans involves an accumulation of genetic and epigenetic changes that lead to alterations in normal lung epithelium, to in situ carcinoma, and finally to invasive and metastatic cancers. The loss of transforming growth factor
Externí odkaz:
https://doaj.org/article/b431d89ea4e441fbb8223b728f6d5aa1
Autor:
Nicole F Neel, Jiqing Sai, Amy-Joan L Ham, Tammy Sobolik-Delmaire, Raymond L Mernaugh, Ann Richmond
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23813 (2011)
Chemotaxis is essential for a number of physiological processes including leukocyte recruitment. Chemokines initiate intracellular signaling pathways necessary for chemotaxis through binding seven transmembrane G protein-couple receptors. Little is k
Externí odkaz:
https://doaj.org/article/2bab39ab5da447f18f05055eca573578
Publikováno v:
Currents in Pharmacy Teaching and Learning. 8:589-597
Objective To assess the reliability and construct validity of the MUSIC Model of Academic Motivation Inventory in a student pharmacist population. Methods The MUSIC Inventory was administered via Qualtrics two weeks prior to mid-semester examinations
Autor:
Robert W. Sprung, Mary Kay Washington, Daniel C. Liebler, Carlos L. Arteaga, Melinda E. Sanders, Misti A. Martinez, Kristen L. Carpenter, Amy-Joan L. Ham
Publikováno v:
Journal of Proteome Research
We compared the reproducibility of multiple reaction monitoring (MRM) mass spectrometry-based peptide quantitation in tryptic digests from formalin-fixed, paraffin-embedded (FFPE) and frozen clear cell renal cell carcinoma tissues. The analyses targe
Autor:
Violeta Sanchez, Carlos L. Arteaga, R Sprung, Amy-Joan L. Ham, Daniel C. Liebler, Melinda E. Sanders, Suzanne Manning
Publikováno v:
Cancer Research. 71:P1-07
HER2 (ERBB2) is overexpressed in about 25% of breast cancers and predicts clinical benefit from trastuzumab, as well as response to anthracycline-based chemotherapy. Fluorescence in situ hybridization (FISH) to detect HER2 gene copy number and immuno
Autor:
Carlos L. Arteaga, Jenny C. Chang, Daniel C. Liebler, Ana M. Gonzalez-Angulo, Amy-Joan L. Ham, N. De Matos Granja-Ingram, Cammie Rinehart, Gordon B. Mills, Bhuvanesh Dave, Brent N. Rexer, Salisha Hill
Publikováno v:
Oncogene
Despite the initial effectiveness of the tyrosine kinase inhibitor lapatinib against HER2 gene-amplified breast cancers, most patients eventually relapse after treatment, implying that tumors acquire mechanisms of drug resistance. To discover these m
Autor:
Karl R. Clauser, Fred E. Regnier, Steven A. Carr, Paul A. Rudnick, Lisa E. Kilpatrick, Dean Billheimer, Thomas A. Neubert, Helene L. Cardasis, Daniel C. Liebler, Cliff Spiegelman, David L. Tabb, Mehdi Mesri, Amy-Joan L. Ham, Christopher R. Kinsinger, Pei Wang, David M. Bunk, Paul Tempst, Asokan Mulayath Variyath, Bradford W. Gibson, Lisa J. Zimmerman, Stephen E. Stein, Lorenzo Vega-Montoto, Jeffrey R. Whiteaker, Susan J. Fisher, Birgit Schilling, Tony J. Tegeler, Kevin A. Kowalski, Ronald K. Blackman, Amanda G. Paulovich, Jacob D. Jaffe, Henry Rodriguez, Mu Wang
Publikováno v:
Journal of Proteome Research. 9:761-776
The complexity of proteomic instrumentation for LC-MS/MS introduces many possible sources of variability. Data-dependent sampling of peptides constitutes a stochastic element at the heart of discovery proteomics. Although this variation impacts the i
Autor:
Mark J. Koury, Zhixiong Xu, Jingping Xie, Stephen J. Brandt, Amy-Joan L. Ham, Scott W. Hiebert, Ying Cai
Publikováno v:
Biochemical and Biophysical Research Communications. 390:295-301
The TAL1 (or SCL) gene, originally discovered through its involvement by a chromosomal translocation in T-cell acute lymphoblastic leukemia, encodes a basic helix-loop-helix (bHLH) transcription factor essential for hematopoietic and vascular develop
Autor:
Helene L. Cardasis, Lei Zhao, Angela M. Jackson, Christopher R. Kinsinger, Richard K. Niles, Jason M. Held, Steven J. Skates, Asokan Mulayath Variyath, Susan E. Abbatiello, David L. Tabb, Daniel C. Liebler, Charles Buck, Tara Hiltke, Mu Wang, Paul A. Rudnick, Terri A. Addona, Jeffrey R. Whiteaker, Ronald K. Blackman, Amanda G. Paulovich, Derek Smith, D. R. Mani, Trenton C. Pulsipher, Lorenzo Vega-Montoto, Mehdi Mesri, Bradford W. Gibson, Asa Wahlander, Michael P. Cusack, David F. Ransohoff, Christoph H. Borchers, Eric B. Johansen, Susan J. Fisher, Simon Allen, Clifford H. Spiegelman, Henry Rodriguez, Steven A. Carr, David M. Bunk, Paul Tempst, Nathan G. Dodder, Fred E. Regnier, Sofia Waldemarson, Hasmik Keshishian, Thomas A. Neubert, N. Leigh Anderson, Steven C. Hall, Birgit Schilling, Jing Li, Tony J. Tegeler, Amy-Joan L. Ham, Lisa J. Zimmerman
Publikováno v:
Nature Biotechnology. 27:633-641
Verification of candidate biomarkers relies upon specific, quantitative assays optimized for selective detection of target proteins, and is increasingly viewed as a critical step in the discovery pipeline that bridges unbiased biomarker discovery to
Publikováno v:
The Journal of General Physiology
Changes in phosphorylation regulate the activity of various ClC anion transport proteins. However, the physiological context under which such regulation occurs and the signaling cascades that mediate phosphorylation are poorly understood. We have exp