Zobrazeno 1 - 10
of 127
pro vyhledávání: '"† and Antonio J. Costa-Filho"'
Autor:
Carlos Y. Fernández, Analu Rocha, Mohammad Azam, Natalia Alvarez, Kim Min, Alzir A. Batista, Antonio J. Costa-Filho, Javier Ellena, Gianella Facchin
Publikováno v:
Inorganics, Vol 11, Iss 10, p 398 (2023)
Coordination compounds of copper exhibit cytotoxic activity and are suitable for the search for novel drug candidates for cancer treatment. In this work, we synthesized three copper(II) carboxylate complexes, [Cu2(3-(4-hydroxyphenyl)propanoate)4(H2O)
Externí odkaz:
https://doaj.org/article/a33e4b5eeecd410193bad9a54b3f2520
Autor:
Natalia Alvarez, Analu Rocha, Victoria Collazo, Javier Ellena, Antonio J. Costa-Filho, Alzir A. Batista, Gianella Facchin
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1345 (2023)
Coordination complexes may act as anticancer agents. Among others, the formation of the complex may facilitate the ligand uptake by the cell. Searching for new copper compounds with cytotoxic activity, the complex Cu-dipicolinate was studied as a neu
Externí odkaz:
https://doaj.org/article/a76adc44a34744b0a3bc66ec74b82e55
Autor:
Carlos Y. Fernández, Natalia Alvarez, Analu Rocha, Javier Ellena, Antonio J. Costa-Filho, Alzir A. Batista, Gianella Facchin
Publikováno v:
Molecules, Vol 28, Iss 2, p 896 (2023)
Searching for new copper compounds which may be useful as antitumor drugs, a series of new [Cu(L-dipeptide)(batho)] (batho:4,7-diphenyl-1,10-phenanthroline, L-dipeptide: Gly-Val, Gly-Phe, Ala-Gly, Ala-Ala, Ala-Phe, Phe-Ala, Phe-Val and Phe-Phe) compl
Externí odkaz:
https://doaj.org/article/e25655d39de041259c1033f036143b1f
Autor:
Raquel Fonseca-Maldonado, Luana P. Meleiro, Luís F. S. Mendes, Luana F. Alves, Sibeli Carli, Lucas D. Morero, Luis G. M. Basso, Antonio J. Costa-Filho, Richard J. Ward
Publikováno v:
Biotechnology for Biofuels, Vol 10, Iss 1, Pp 1-11 (2017)
Abstract Background The Bacillus subtilis endo-β-1,4-glucanase (BsCel5A) hydrolyzes β-1,3-1,4-linked glucan, and the enzyme includes a family 3 carbohydrate-binding module (CBM3) that binds β-1,4-linked glucan. Methods Here we investigate the BsCe
Externí odkaz:
https://doaj.org/article/e226be144c934782a05dbb7e70717051
Autor:
Nathan Nunes Evangelista, Mariana C Micheletto, Luis Felipe Santos Mendes, Antonio J Costa-Filho
Polycyclic aromatic hydrocarbons (PAHs) are molecules with two or more fused aromatic rings that occur naturally in the environment due to incomplete combustion of organic substances. However, the increased demand for fossil fuels in recent years has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::269a23525c0245424fbdb3ff1aa13263
https://doi.org/10.1101/2023.05.29.542454
https://doi.org/10.1101/2023.05.29.542454
Autor:
Marco A S Kadowaki, Anikó Várnai, John-Kristian Jameson, Ana E T Leite, Antonio J Costa-Filho, Patricia S Kumagai, Rolf A Prade, Igor Polikarpov, Vincent G H Eijsink
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202148 (2018)
Thermophilic fungi are a promising source of thermostable enzymes able to hydrolytically or oxidatively degrade plant cell wall components. Among these enzymes are lytic polysaccharide monooxygenases (LPMOs), enzymes capable of enhancing biomass hydr
Externí odkaz:
https://doaj.org/article/af7dbd3d5da247f88350202833feb109
Publikováno v:
Biophysical Reviews
The 20th IUPAB Congress took place online, together with the annual meetings of the Brazilian Biophysical Society and the Brazilian Society for Biochemistry and Molecular Biology, from the 4th to the 8th of October, 2021. The ten keynote lectures, 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eff81d12d9af7fc7418c33cca956fb8
http://europepmc.org/articles/PMC8590420
http://europepmc.org/articles/PMC8590420
Autor:
Marília L. Cirqueira, Leandro O. Bortot, Maytê Bolean, Mariana A.A. Aleixo, Pedro H. Luccas, Antonio J. Costa-Filho, Ana Paula Ramos, Pietro Ciancaglini, M. Cristina Nonato
Publikováno v:
International journal of biological macromolecules. 221
Due to its severe burden and geographic distribution, Chagas disease (CD) has a significant social and economic impact on low-income countries. Benznidazole and nifurtimox are currently the only drugs available for CD. These are prodrugs activated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe46af5a61fe1820225e0f007748c93d
https://pubmed.ncbi.nlm.nih.gov/36100001
https://pubmed.ncbi.nlm.nih.gov/36100001
Autor:
Natalia Alvarez, Priscilla Freddi, Stephanie Castellani, Nicolás Veiga, Gianella Facchin, Antonio J. Costa-Filho
Publikováno v:
Brazilian Journal of Physics. 52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d48d78ae42de99dd09fedff6755a79c
https://doi.org/10.1007/s13538-022-01114-7
https://doi.org/10.1007/s13538-022-01114-7
Autor:
Antonio J. Costa-Filho, Natália A. Fontana, Luis F.S. Mendes, Vladimir N. Uversky, S. Thirupathi Reddy
Publikováno v:
International Journal of Biological Macromolecules. 164:3632-3644
Golgi Reassembly and Stacking Proteins (GRASPs) were firstly described as crucial elements in determining the structure of the Golgi complex. However, data have been accumulating over the years showing GRASPs can actually participate in various cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cbb44a59aef645ac50f3784ef63fa1
https://doi.org/10.1016/j.ijbiomac.2020.08.203
https://doi.org/10.1016/j.ijbiomac.2020.08.203