Zobrazeno 1 - 8
of 8
pro vyhledávání: '"‘OPTI-CLOT' study group"'
Autor:
Michael E. Cloesmeijer, Erik Sjögren, Sjoerd F. Koopman, Peter. J. Lenting, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT study group and SYMPHONY consortium
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 10, Pp 1630-1640 (2024)
Abstract Patients with severe and sometimes moderate hemophilia B are prophylactically treated with factor IX concentrates to prevent bleeding. For some time now, various extended terminal half‐life (EHL) recombinant factor IX concentrates are avai
Externí odkaz:
https://doaj.org/article/5f163a5353a04a9587192c9f9d3e1653
Autor:
Alexander Janssen, Mark Hoogendoorn, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT Study Group and SYMPHONY Consortium
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 8, Pp 1100-1110 (2022)
Abstract In population pharmacokinetic (PK) models, interindividual variability is explained by implementation of covariates in the model. The widely used forward stepwise selection method is sensitive to bias, which may lead to an incorrect inclusio
Externí odkaz:
https://doaj.org/article/0ab8e6d545d7478e9376b677b1290db2
Autor:
Alexander Janssen, Frank W. G. Leebeek, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT study group and SYMPHONY consortium
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 7, Pp 934-945 (2022)
Abstract Nonlinear mixed effect (NLME) models are the gold standard for the analysis of patient response following drug exposure. However, these types of models are complex and time‐consuming to develop. There is great interest in the adoption of m
Externí odkaz:
https://doaj.org/article/9c0772ba25f9456fb3e8391b85d47457
Autor:
Jessica M. Heijdra, Ferdows Atiq, Wala Al Arashi, Quincy Kieboom, Esmee Wuijster, Karina Meijer, Marieke J. H. A. Kruip, Frank W. G. Leebeek, Marjon H. Cnossen, in collaboration with the OPTI‐CLOT Study Group
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 6, Pp n/a-n/a (2022)
Abstract Background Individuals with von Willebrand disease (VWD) require desmopressin testing because of interindividual response differences. However, testing is burdensome, while not all patients may need extensive testing. Objectives To provide v
Externí odkaz:
https://doaj.org/article/fef425826bc741c78576e14267ed4a79
Akademický článek
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Autor:
“OPTI‐CLOT" study group, Nederlof, Angelique1, Cnossen, Marjon H.1, Mathôt, Ron A. A.2, Leebeek, Frank W. G.3, Fijnvandraat, Karin4, Fischer, Kathelijn5
Publikováno v:
Haemophilia. Sep2018, Vol. 24 Issue 5, pe369-e372. 4p. 1 Chart.
Autor:
Nederlof, Angelique, Mathôt, Ron A A, Leebeek, Frank W G, Fijnvandraat, Karin, Fischer, Kathelijn, Cnossen, Marjon H, 'OPTI-CLOT' study group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10691::9ee966098b62eef40f4b218c103d9fdd
https://dspace.library.uu.nl/handle/1874/372457
https://dspace.library.uu.nl/handle/1874/372457
Autor:
Lock, J, de Bekker-Grob, E W, Urhan, G, Peters, M, Meijer, K, Brons, P, van der Meer, F J M, Driessens, M H E, Collins, P W, Fijnvandraat, K, Leebeek, F W G, Cnossen, M H, ‘OPTI-CLOT’ study group, Schutgens, REG
INTRODUCTION: Patients', parents' and providers' preferences with regard to medical innovations may have a major impact on their implementation. AIM: To evaluate barriers and facilitators for individualized pharmacokinetic (PK)-guided dosing of proph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10691::e13d3b5c71646586f46ded7ea47d1c18
https://dspace.library.uu.nl/handle/1874/345817
https://dspace.library.uu.nl/handle/1874/345817