High-dose vitamin D supplementation in pregnancy and 25(OH)D sufficiency in childhood reduce the risk of fractures and improve bone mineralization in childhood: Follow-up of a randomized clinical trial

Autor: Nicklas Brustad, Bo L. Chawes, Jonathan Thorsen, Martin Krakauer, Jessica Lasky-Su, Scott T. Weiss, Jakob Stokholm, Klaus Bønnelykke, Hans Bisgaard

Publikováno v: EClinicalMedicine, Vol 43, Iss, Pp 101254-(2022)
eClinicalMedicine
Brustad, N, Chawes, B L, Thorsen, J, Krakauer, M, Lasky-Su, J, Weiss, S T, Stokholm, J, Bønnelykke, K & Bisgaard, H 2022, ' High-dose vitamin D supplementation in pregnancy and 25(OH)D sufficiency in childhood reduce the risk of fractures and improve bone mineralization in childhood : Follow-up of a randomized clinical trial ', EClinicalMedicine, vol. 43, 101254 . https://doi.org/10.1016/j.eclinm.2021.101254
EClinicalMedicine

Background: Exposure to vitamin D in early life has been associated with improved bone mineralization, but no studies have investigated the combined effect of pregnancy supplementation and childhood 25(OH)D concentrations on bone health. Methods: We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c7f0dda05a95ff040299d676ae24ba
http://www.sciencedirect.com/science/article/pii/S2589537021005356

Effect of ErhBMP-2-loaded β-tricalcium phosphate on ulna defects in the osteoporosis rabbit model

Autor: Weng-Ling Yeh, Pei Wei Weng, Jian-Ming Chen, Tse-Yin Huang, Chang-Chin Wu

Publikováno v: Bone Reports, Vol 14, Iss, Pp 100739-(2021)
Bone Reports

Purpose Autografts, the gold standard treatment for large bone defects, present complications, especially in conditions with reduced bone-repair capacity, such as osteoporosis. Escherichia coli-derived recombinant human bone morphogenesis protein-2 (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c142e2dd9044d8b4defa410e19089f06
http://www.sciencedirect.com/science/article/pii/S235218722030499X

Differential time-dependent transcriptional changes in the osteoblast lineage in cortical bone associated with sclerostin antibody treatment in ovariectomized rats

Autor: Rogely W. Boyce, Michael S. Ominsky, Kathrin Locher, Ian Pyrah, Scott Taylor, Rong Hu, Efrain Pacheco

Publikováno v: Bone Reports, Vol 8, Iss, Pp 95-103 (2018)
Bone Reports

Inhibition of sclerostin with sclerostin antibody (Scl-Ab) results in stimulation of bone formation on cancellous (Cn), endocortical (Ec), and periosteal (Ps) surfaces in rodents and non-human primates. With long-term dosing of Scl-Ab, the increase i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc1af9e53755cdc92068b41eaed0ec2
http://www.sciencedirect.com/science/article/pii/S2352187218300147

High-fat/high-sucrose diet results in higher bone mass in aged rats

Autor: Susumu Sakata, Akira Minematsu, Yasue Nishii

Publikováno v: Bone Reports
Bone Reports, Vol 8, Iss, Pp 18-24 (2018)

Intake of high-fat/high-sucrose (HFS) diet or high fat diet influences bone metabolism in young rodents, but its effects on bone properties of aged rodents still remain unclear. This study aimed to examine the effects of HFS diet intake on trabecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3959f184a13b5aaa18c431da7f3cbcd7
https://doi.org/10.1016/j.bonr.2018.01.001

Evaluation of bone mineralization in former preterm born children: Phalangeal quantitative ultrasound cannot replace dual-energy X-ray absorptiometry

Autor: Mayke E. van der Putten, Arno van Heijst, Carmen M.T. Lageweg, Johannes B. van Goudoever, V. Christmann, Ton Feuth, Martin Gotthardt

Publikováno v: Bone Reports, Vol 8, Iss, Pp 38-45 (2018)
Bone Reports, 8, 38-45
Bone Reports, 8, pp. 38-45
Bone Reports
Bone Reports, 8, 38-45. Elsevier Inc.
Lageweg, C M T, van der Putten, M E, van Goudoever, J B, Feuth, T, Gotthardt, M, van Heijst, A F J & Christmann, V 2018, ' Evaluation of bone mineralization in former preterm born children: Phalangeal quantitative ultrasound cannot replace dual-energy X-ray absorptiometry ', Bone Reports, vol. 8, pp. 38-45 . https://doi.org/10.1016/j.bonr.2018.01.004
Bone reports, 8, 38-45. Elsevier Inc.

Background Preterm infants are at risk of impaired bone health in later life. Dual-energy X-ray absorptiometry-scan (DXA) is the gold standard to determine bone mineralization. Phalangeal quantitative ultrasound (pQUS) is an alternative technique tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3738b97af8c9be0e79e0b4bb751ab339
http://www.sciencedirect.com/science/article/pii/S2352187218300044