Zobrazeno 1 - 10
of 161
pro vyhledávání: '"острая токсичность"'
Autor:
M. V. Filimonova, A. S. Saburova, L. I. Shevchenko, V. M. Makarchuk, A. A. Lychagin, A. S. Filimonov
Publikováno v:
Радиационная гигиена, Vol 14, Iss 1, Pp 68-74 (2021)
According to leading experts, the vast arsenal of radioprotective agents available in the world today does not fully meet modern practical needs, both in the field of radiation protection, and in the prevention and treatment of complications of radio
Externí odkaz:
https://doaj.org/article/6331e11be97d44b6bb0dbe440939c556
Publikováno v:
Российский паразитологический журнал, Vol 12, Iss 2, Pp 62-67 (2019)
The purpose of the research: to study acute toxicity and anthelmintic efficacy of khimedol, a new anthelmintic preparation. Materials and methods. Khimedol, anthelmintic preparation which was received by means of streamlined synthesis in the Institut
Externí odkaz:
https://doaj.org/article/726def794b4b400ab24c245777d97d42
Autor:
S. V. Alekseeva, A. V. Sorokina, A. V. Volkova, V. V. Zabrodina, I. A. Miroshkina, K. S. Kachalov, I. V. Alekseev, A. D. Zaharov, P. Yu. Povarnina, A. D. Durnev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 46-50 (2019)
Resume. The study of acute and chronic toxicity of the finished dosage form (SFF) GSB-106, the active substance of which is the substituted dimeric peptide, hexamethylenediamine bis (N-monosuccinyl-L-seryl-L-lysine), which has antidepressant and neur
Externí odkaz:
https://doaj.org/article/e0abd8e20ff84910a7ef8e1979857f06
Autor:
A. V. Sorokina, S. V. Alekseeva, I. A. Miroshkina, A. V. Volkova, V. V. Zabrodina, K. S. Kachalov, I. V. Alekseev, A. D. Zaharov, P. Yu. Povarnina, A. D. Durnev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 51-58 (2019)
Resume. The paper presents the data of preclinical studies of the acute and chronic toxicity of the finished dosage form of the compound GK-2, which has neuroprotective properties. It has been established that GK-2 does not cause the death of animals
Externí odkaz:
https://doaj.org/article/db57a712217b442a81b26cd8d5f115e4
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 65-70 (2018)
Resume. Relevance. The acute toxicity evaluation is the anecessary stage of preclinical research of the new original anxiolytic drug GML-1. The present investigation aim is study of the GML-1 acute toxicity. Methods. GML-1 was administered once orall
Externí odkaz:
https://doaj.org/article/22cfcf93faf6444296ff674403a38424
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 0, Iss 3, Pp 36-41 (2018)
Animal experiments are fundamental for the biomedical science. The development of new drugs is always associated with a large number of preclinical experiments in animals. Experimental data make it possible to predict the drug efficacy and safety in
Externí odkaz:
https://doaj.org/article/902b3dcb3e6a42f6bab4afdfd2725033
Publikováno v:
Российский паразитологический журнал, Vol 41, Iss 3, Pp 263-265 (2019)
Objective of research. The aim of this study was to estimate of acute oral toxicity for white mice and determine the hazard class of chlorfenapyr-containing baits for mammals. Materials and methods. The material of study was the insecticidal chlorfen
Externí odkaz:
https://doaj.org/article/6acfa530e41249b3afcc5bf22043d658
Анализ новых комплексных соединений на основе семикарбазида и хинальдиновой кислоты методом in silico для консенсусной оценки прогнозируе
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01fc06ae9dfb2a0bb6ba892cb9b0f328
Анализ новых комплексных соединений на основе семикарбазида и хинальдиновой кислоты методом in silico для консенсусной оценки прогнозируе
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7283ad96941520ebcf50b6585cefac64
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 39-42 (2017)
It was determined endurable, toxic and fatal doses of a new original anti-migraine medicine Tropoxin in tablet form at unitary oral and intraperitoneal introduction to outbreeding white mice and rats. Periods of intoxication and death of animals with
Externí odkaz:
https://doaj.org/article/a81f6623102840c4b0c7fc57cdfddb3d