Zobrazeno 1 - 10
of 2 226
pro vyhledávání: '"δ opioid receptor"'
Autor:
Yoshihisa UENOYAMA, Miku NONOGAKI, Hitomi TSUCHIDA, Marina TAKIZAWA, Sena MATSUZAKI, Naoko INOUE, Hiroko TSUKAMURA
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 5, Pp 327-337 (2024)
In mammals, secretion of tonic (pulsatile) gonadotropin-releasing hormone (GnRH)/luteinizing hormone (LH) is often suppressed during lactation. Suppression of GnRH/LH pulses in lactating dams is assumed to be caused by suckling stimuli and a chronic
Externí odkaz:
https://doaj.org/article/1de02d5e56d340ed8d509f7bff937d8b
Publikováno v:
Medicine in Drug Discovery, Vol 21, Iss , Pp 100176- (2024)
Despite being the most widely prescribed and misused type of medication, opioids continue to function as robust pain relief agents; however, overdosing is a significant cause of fatalities among opioid users. The δ-opioid receptor (DOR) has immense
Externí odkaz:
https://doaj.org/article/d343eaea64cb4d81930ddeaa6fdd245a
Autor:
Yuki Moriya, Yoshiyuki Kasahara, Masafumi Shimada, Yasufumi Sakakibara, Hideaki Fujii, Hiroshi Nagase, Soichiro Ide, Kazutaka Ikeda, F. Scott Hall, George R. Uhl, Ichiro Sora
Publikováno v:
Journal of Pharmacological Sciences, Vol 151, Iss 3, Pp 135-141 (2023)
Previous pharmacological data have shown the possible existence of functional interactions between μ- (MOP), κ- (KOP), and δ-opioid receptors (DOP) in pain and mood disorders. We previously reported that MOP knockout (KO) mice exhibit a lower stre
Externí odkaz:
https://doaj.org/article/09bb7dc779c5447daf3862372f76af88
Autor:
Runjie Guo, Yongjie Zhang, Yue Geng, Ping Chen, Tiantian Fu, Yong Xia, Ren Zhang, Yuan Zhu, Jingling Jin, Nange Jin, Hong Xu, Xuesong Tian
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2023)
Objectives: Retinal ischemia-reperfusion injury (RIRI) is the common pathological basis of many ophthalmic diseases in the later stages, and inflammation is the primary damage mechanism of RIRI. Our study aimed to assess whether electroacupuncture (E
Externí odkaz:
https://doaj.org/article/30d62917ef9c4fb2b893c051d6afe990
Akademický článek
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Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Hypoxia and ischemia cause inflammatory injury and critically participate in the pathogenesis of various diseases in various organs. However, the protective strategies against hypoxic and ischemic insults are very limited in clinical settings up to d
Externí odkaz:
https://doaj.org/article/cb542427a4ba48f2a4808efd5ae7cf51
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Microglia are involved in the regulation of cerebral homeostasis and pathogen confrontation. There is, however, evidence showing that excessive microglia activation is implicated in various age-related cerebral diseases. On the other hand, microglia
Externí odkaz:
https://doaj.org/article/e203f9d7b22a4fa4b0276d05b89e18ce
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Hypoxic-ischemic brain damage (HIBD) is a relatively common malignant complication that occurs in newborn infants, but promising therapies remain limited. In this study, we focused on the role of miR-326 and its target gene δ-opioid recepto
Externí odkaz:
https://doaj.org/article/642fd8c0094544dab2ec663d0d4ace58
Autor:
Kalpana Subedi, Hongmin Wang
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 1, Pp 20-24 (2020)
Ischemic stroke is a global epidemic condition due to an inadequate supply of blood and oxygen to a specific area of brain either by arterial blockage or by narrowing of blood vessels. Despite having advancement in the use of thrombolytic and clot re
Externí odkaz:
https://doaj.org/article/90faf1200e8446b883344569174e9392