Zobrazeno 1 - 10
of 599
pro vyhledávání: '"γδT cells"'
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 6, Pp 763-771 (2024)
Objective To construct chimeric antigen receptors modified γδT cells targeting at BCMA (BCMA CAR-γδT) and to evaluate its efficacy of anti-multiple myeloma in vitro. Methods Lentiviral vectors containing BCMA single-chain variable fragment were c
Externí odkaz:
https://doaj.org/article/724286e5e0c244a399c78fa0f26bea6b
Autor:
Yinxiao Chen, Zhaodong Li, Liding Bai, Bin Lu, Yanfei Peng, Pengjuan Xu, Xinbo Song, Yuhong Bian, Xiangling Wang, Shuwu Zhao
Publikováno v:
FEBS Open Bio, Vol 14, Iss 6, Pp 1011-1027 (2024)
Tumor immunotherapy can be a suitable cancer treatment option in certain instances. Here we investigated the potential immunomodulatory effect of oral glycyrrhiza polysaccharides (GCP) on the antitumor function of γδT cells in intestinal epithelial
Externí odkaz:
https://doaj.org/article/fb95ea00ecc04175a947b1ff9c5c6624
Autor:
Zhixiong Zhu, Hexian Li, Qizhong Lu, Zongliang Zhang, Jia Li, Zeng Wang, Nian Yang, Zhengyu Yu, Chen Yang, Yongdong Chen, Huaqing Lu, Wei Wang, Ting Niu, Chunlai Nie, Aiping Tong
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Clinical trials of Chimeric Antigen Receptor T‐cell (CAR‐T) therapy have demonstrated remarkable success in treating both solid tumors and hematological malignancies. Nanobodies (Nbs) have emerged as promising antigen‐targeting domains
Externí odkaz:
https://doaj.org/article/8b15ce605dcc484b9a66e75fbf9aa14f
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Tumor immune microenvironment (TIME) is a tiny structure that contains multiple immune cell components around tumor cells, which plays an important role in tumorigenesis, and is also the potential core area of activated immunotherapy. How immune cell
Externí odkaz:
https://doaj.org/article/5bd95d65ed9043da83c2205797bf24c2
Autor:
A. P. Toptygina
Publikováno v:
Медицинская иммунология, Vol 26, Iss 3, Pp 449-464 (2024)
In addition to the subsets of T lymphocytes and innate lymphocytes (innate lymphoid cells), the well-known players in adaptive immunity, there is an intermediate group of lymphocytes (innate-like cells) that already possess the T cell receptor, but w
Externí odkaz:
https://doaj.org/article/4126afcaedd24543a44ebac0bde513b4
Publikováno v:
Vestnik Dermatologii i Venerologii, Vol 100, Iss 1, Pp 31-37 (2024)
Psoriasis is a frequently occurring inflammatory skin disease. Fundamental research into the pathogenesis of psoriasis has significantly expanded our understanding of skin immunology, which has enabled the introduction of innovative and highly effect
Externí odkaz:
https://doaj.org/article/7a6dea464dd24a68b1fb1b0dd4d495cc
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 721-736 (2024)
Hong Di,* Xinxin Han,* Yue Yin, Yun Zhang, Xuejun Zeng Department of Family Medicine & Division of General Internal Medicine, Department of Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, State Key Labora
Externí odkaz:
https://doaj.org/article/e502c40175614584851fabba8b3d8141
Autor:
Lucía Paniagua-Herranz, Cristina Díaz-Tejeiro, Adrián Sanvicente, Jorge Bartolomé, Cristina Nieto-Jiménez, Alberto Ocana
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Therapeutic strategies targeting non-adaptive immune cells are currently in clinical development. γδT cells are a small subtype of T cells (1-10% of total T cells) that mediate their effector function without the necessity of the antigen presenting
Externí odkaz:
https://doaj.org/article/7d774cf911074c7781f4b84be65f5c1a
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Atherosclerosis poses a significant threat to human health, impacting overall well-being and imposing substantial financial burdens. Current treatment strategies mainly focus on managing low-density lipids (LDL) and optimizing liver functions. Howeve
Externí odkaz:
https://doaj.org/article/f66d68614a7742709e6ea25c93339f64
Publikováno v:
Mycology, Vol 15, Iss 1, Pp 57-69 (2024)
Candida albicans is one of the most common opportunistic fungi in cancer patients. This study explored the influence of C. albicans on gut microbiota in oral tumour-bearing mice by means of 16S rRNA sequencing and ITS sequencing. It was found that C.
Externí odkaz:
https://doaj.org/article/831d4574474746439d818443b9551576