Zobrazeno 1 - 10
of 2 649
pro vyhledávání: '"γδ T‐cells"'
Autor:
Junhong Ai, Haijuan Xiao, Linlin Zhang, Honghao Ma, Dong Wang, Dilara Dilmurat, Ran Wang, Zhengde Xie
Publikováno v:
Italian Journal of Pediatrics, Vol 50, Iss 1, Pp 1-4 (2024)
Abstract Chronic active Epstein-Barr virus infection (CAEBV) is a progressive and life-threatening disease characterized by persistent or recurrent EBV activation. It has been reported that, γδ T cells, a type of cytotoxic lymphocyte, play a critic
Externí odkaz:
https://doaj.org/article/ae4d981bfcb54508b812f638be6fa696
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Congenital cytomegalovirus (cCMV) infection can lead to a range of adverse outcomes. The majority of cCMV neonates with clinical symptoms are infected postnatally; however, established cases of intrauterine infection are uncommon,
Externí odkaz:
https://doaj.org/article/2614ec6330ad4025b20195345af3f59a
Autor:
Faisal Al Agrafi, Ahmed Gaballa, Paula Hahn, Lucas C. M. Arruda, Adrian C. Jaramillo, Maartje Witsen, Sören Lehmann, Björn Önfelt, Michael Uhlin, Arwen Stikvoort
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Despite the considerable progress in acute myeloid leukemia (AML) treatment, relapse after allogeneic hematopoietic stem cell transplantation (HSCT) is still frequent and associated with a poor prognosis. Relapse has been shown to be correlated with
Externí odkaz:
https://doaj.org/article/ca872293916e48378654b84df2a21822
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In recent years, the use of chimeric antigen receptor (CAR)-T cells has emerged as a promising immunotherapy in multiple diseases. CAR-T cells are T cells genetically modified to express a surface receptor, known as CAR, for the targeting of cognate
Externí odkaz:
https://doaj.org/article/2034b41992f04b37a7e0df79baa6c910
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Gamma delta (γδ) T cells demonstrate strong cytotoxicity against diverse cancer cell types in an MHC-independent manner, rendering them promising contenders for cancer therapy. Although amplification and adoptive transfer of γδ T cells a
Externí odkaz:
https://doaj.org/article/c43fdf6e702a468791d6c388ff0a63c9
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Undeniably, cancer immunotherapies have expanded the spectrum of cancer treatment, however, some patients do not respond to immunotherapies. This scenario is no different for lung cancer, whose two main types, non-small cell lung cancer (NSC
Externí odkaz:
https://doaj.org/article/69bfd3fa7c6a4ad7981fd82e32a8349f
Autor:
Yunxiong Wei, Guangyong Sun, Yang Yang, Mingyang Li, Shimeng Zheng, Xiyu Wang, Xinjie Zhong, Zihan Zhang, Xiaotong Han, Haiyan Cheng, Dong Zhang, Xueling Mei
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Psoriasis is a chronic immune-mediated skin condition. Although biologic treatments are effective in controlling psoriasis, some patients do not respond or lose response to these therapies. Thus, new strategies for psoriasis treat
Externí odkaz:
https://doaj.org/article/14a0b7e707184f559c80ca7b3905f442
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
γδ T-cells are a rare population of T-cells with both adaptive and innate-like properties. Despite their low prevalence, they have been found to be implicated various human diseases. γδ T-cell infiltration has been associated with improved clinic
Externí odkaz:
https://doaj.org/article/4d003fdcc7094e72971a427d4acca1ef
Autor:
Yarob Ibraheem, Ganchimeg Bayarsaikhan, Maria Lourdes Macalinao, Kazumi Kimura, Katsuyuki Yui, Taiki Aoshi, Shin-Ichi Inoue
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
γδ T cells facilitate the CD4+ T helper 1 (Th1) cell response against Plasmodium infection by activating conventional dendritic cells (cDCs), although the underlying mechanism remains elusive. Our study revealed that γδ T cells promote the comple
Externí odkaz:
https://doaj.org/article/af27847c4be24183adb6ba57fc052517
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundGamma-delta (γδ) T cells are a major immune cell subset in pigs. Approximately 50% of circulating T cells are γδ T cells in young pigs and up to 30% in adult sows. Despite this abundance, the functions of porcine γδ T cells are mostly
Externí odkaz:
https://doaj.org/article/62a118bca24048aa972a2d42a418934f