Zobrazeno 1 - 10
of 492
pro vyhledávání: '"β2-glycoprotein I"'
Publikováno v:
Klinicist, Vol 18, Iss 1, Pp 78-87 (2024)
Antiphospholipid syndrome (APS) is a systemic autoimmune pathology characterized by thrombotic manifestation associated with antiphospholipid antibodies (aPL) and phospholipid-binding proteins circulation. Long-term anticoagulant therapy is a corners
Externí odkaz:
https://doaj.org/article/f4e2cffe008c42558144473cabe0ec9b
Publikováno v:
Rheumatology & Autoimmunity, Vol 3, Iss 3, Pp 131-139 (2023)
Abstract Antiphospholipid syndrome (APS) is typically characterized by increased levels of three classes of antiphospholipid antibodies, namely lupus anticoagulant, anti‐β2‐glycoprotein I (anti‐β2GPI), and anticardiolipin antibodies. β2‐Gl
Externí odkaz:
https://doaj.org/article/b2931fb11b894367a54bd6509ccc4024
Publikováno v:
Immunological Medicine, Vol 44, Iss 2, Pp 124-135 (2021)
Antibodies specific for cardiolipin (CL)-β2-glycoprotein I (β2GPI) are known to induce tissue factor (TF) expression by monocytes and endothelial cells which leads to a prothrombotic state in antiphospholipid syndrome (APS), but the mechanism is no
Externí odkaz:
https://doaj.org/article/01df479967374dbda7921f75dac4a14a
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antiphospholipid antibodies (aPL) are mandatory for the diagnosis but are also a risk factor for the antiphospholipid syndrome (APS) clinical manifestations. Lupus anticoagulant (LA), anticardiolipin (aCL), and anti-beta2 glycoprotein I (β2GPI) assa
Externí odkaz:
https://doaj.org/article/acb269c992f7494794f7c859703c8185
Publikováno v:
Lipids in Health and Disease, Vol 16, Iss 1, Pp 1-10 (2017)
Abstract Background New evidence has shown that reduced β2-glycoprotein I (β2GPI) has anti-oxidative stress and anti-inflammatory activity. However, the details are still poorly understood. This study aims to prepare stable reduced β2GPI with its
Externí odkaz:
https://doaj.org/article/eaefc0bc307a4f2291449da0c5fedd0e
Autor:
Maria Orietta Borghi, Asmaa Beltagy, Emirena Garrafa, Daniele Curreli, Germana Cecchini, Caterina Bodio, Claudia Grossi, Simonetta Blengino, Angela Tincani, Franco Franceschini, Laura Andreoli, Maria Grazia Lazzaroni, Silvia Piantoni, Stefania Masneri, Francesca Crisafulli, Duilio Brugnoni, Maria Lorenza Muiesan, Massimo Salvetti, Gianfranco Parati, Erminio Torresani, Michael Mahler, Francesca Heilbron, Francesca Pregnolato, Martino Pengo, Francesco Tedesco, Nicola Pozzi, Pier Luigi Meroni
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundCritically ill patients with coronavirus disease 2019 (COVID-19) have a profound hypercoagulable state and often develop coagulopathy which leads to organ failure and death. Because of a prolonged activated partial-thromboplastin time (aPTT
Externí odkaz:
https://doaj.org/article/5b099cdbcb0444d7a098a9fdc716fc5b
Publikováno v:
Life, Vol 11, Iss 8, p 801 (2021)
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by autoreactive B and T cells against β2-glycoprotein I (B2GPI), with vascular thrombosis or obstetrical complications. Dendritic cells (DCs) are crucial in the generation of aut
Externí odkaz:
https://doaj.org/article/f6453339999f42c5adceb38ea7d1f151
Akademický článek
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Autor:
Yamada, Kenji Tanimura, Shigeru Saito, Sayaka Tsuda, Yosuke Ono, Hajime Ota, Shinichiro Wada, Masashi Deguchi, Mikiya Nakatsuka, Takeshi Nagamatsu, Tomoyuki Fujii, Gen Kobashi, Hisashi Arase, Hideto
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10958
Anti-β2-glycoprotein I/HLA-DR (anti-β2GPI/HLA-DR) antibody has been reported to be associated with antiphospholipid syndrome and recurrent pregnancy loss (RPL). We conducted a prospective multicenter cross-sectional study aimed at evaluating whethe
Publikováno v:
Molecules, Vol 26, Iss 9, p 2492 (2021)
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the production of β2-glycoprotein I (β2GPI)-dependent autoantibodies, with vascular thrombosis or obstetrical complications. Around 20% of APS patients are refractory to curr
Externí odkaz:
https://doaj.org/article/4270f8980401455b8f5438b8b3f5806b