Zobrazeno 1 - 10
of 831
pro vyhledávání: '"β2-adrenergic receptor"'
Autor:
Qi Jia, Yinyin Zhou, Li Song, Ximeng Shi, Xuan Jiang, Ruizhi Tao, Aiyun Wang, Yuanyuan Wu, Zhonghong Wei, Yinan Zhang, Xiaoman Li, Yin Lu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 7, Pp 100934- (2024)
Recent studies have shown that stress can substantially facilitate breast cancer metastasis, which can be reduced by nonselective β1/β2-adrenergic receptor (β1/β2-AR) blocker. However, several side effects were identified. Thus, it is extremely w
Externí odkaz:
https://doaj.org/article/3f195f7905b14f668ed6e7891f94f7df
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 17891-17900 (2023)
Abstract Background Vascular endothelial growth factor (VEGF) was initially known as vascular permeability factor and identified as a driver of tumour angiogenesis. Recently, its role in supporting an immunosuppressive tumour microenvironment was dem
Externí odkaz:
https://doaj.org/article/167becbf3b684e7d9079b03d33c074fb
Publikováno v:
Iranian Journal of Immunology, Vol 20, Iss 1, Pp 16-25 (2023)
Background: Recent research in our laboratory shows that CD4+ T cells express the β2 adrenergic receptor (β2-AR), and the sympathetic neurotransmitter norepinephrine regulates the function of T cells via β2-AR signaling. However, the immunoregulat
Externí odkaz:
https://doaj.org/article/42a1518c6f70439cbd5db4704b50ebd1
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/8840a5369fb341f09087aa7f858bca6a
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 423 (2024)
This study assessed the suitability of the complementarity-determining region 2 (CDR2) of the nanobody (Nb) as a template for the derivation of nanobody-derived peptides (NDPs) targeting active-state β2-adrenergic receptor (β2AR) conformation. Sequ
Externí odkaz:
https://doaj.org/article/a2834c4a3f96422ba8ccea76a859eb4b
Akademický článek
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Akademický článek
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Autor:
Saereh Hosseindoost, Seyed Mojtaba Mousavi, Ahmad Reza Dehpour, Seyed Amirhossein Javadi, Babak Arjmand, Ali Fallah, Mahmoudreza Hadjighassem
Publikováno v:
Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 76-87 (2022)
Glioblastoma multiforme (GBM) is the most invasive form of primary brain astrocytoma. Gene therapy using the herpes simplex virus thymidine kinase/ganciclovir (HSV-TK/GCV) is a new strategy for GBM treatment. As the connexin 43 (Cx43) levels are down
Externí odkaz:
https://doaj.org/article/e06ab83454df478392e62d14327a3808
Autor:
Yang Xiaochun, Liang Xuegang, Guo Haohui, Ma Long, Jian Li, Zhao Xin, Wang Jian, Yang Lvlin, Meng Zhiqiang, Jin Qunhua
Publikováno v:
Open Medicine, Vol 17, Iss 1, Pp 1031-1044 (2022)
An important causative factor in osteoarthritis (OA) is the abnormal mechanical stress-induced bone remodeling of the subchondral bone. β2-adrenergic receptor (Adrb2) plays a major role in mechanical stresses that induce bone remodeling. The medial
Externí odkaz:
https://doaj.org/article/aa328e50e4c649f8b367bcf8c08dd62f
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 6360-6374 (2022)
G protein-coupled receptors (GPCRs) are promising drug targets because they play a large role in physiological processes by modulating diverse signaling pathways in the human body. The GPCR-mediated signaling pathways are regulated by four types of l
Externí odkaz:
https://doaj.org/article/ad658ad191854517bf4e5433cfb433c6