Zobrazeno 1 - 10
of 688
pro vyhledávání: '"β1 integrin"'
Autor:
Léo-Paul Tricou, William Mouton, Andréa Cara, Sophie Trouillet-Assant, Daniel Bouvard, Frédéric Laurent, Alan Diot, Jérôme Josse
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Staphylococcus aureus main internalization mechanism in osteoblasts relies on a tripartite interaction between bacterial fibronectin-binding proteins, extracellular matrix soluble fibronectin, and osteoblasts’ β1 integrins. Caveolins, and
Externí odkaz:
https://doaj.org/article/43219f17f5b4416dbe0418f83e74c908
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-18 (2024)
Abstract Background The involvement of tetraspanins in cancer development has been widely implicated. In this study, the function and molecular mechanisms of tetraspanin 3 (TSPAN3) in non-small cell lung cancer (NSCLC) cells were explored. Methods Ti
Externí odkaz:
https://doaj.org/article/ae027286651c465396b7230f19b9f7f1
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36595- (2024)
Background: Layilin (LAYN) plays an important role in tumor progression, invasion, and metastasis; however, its role in cholangiocarcinoma (CHOL) has not been elucidated. Methods: We utilized the GEPIA, STRING, and hTFtarget databases for bioinformat
Externí odkaz:
https://doaj.org/article/117e38d86e334b3f86953722477681f7
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Interactions between extracellular matrix (ECM) proteins and β1 integrins play an essential role maintaining vascular integrity in the brain, particularly under vascular remodeling conditions. As blood vessels in the spinal cord are reporte
Externí odkaz:
https://doaj.org/article/2087fb5ca2174f71b2bd6bae24a15573
Autor:
Franziska Wirth, Caren Zoeller, Alexander Lubosch, Jutta Schroeder-Braunstein, Guido Wabnitz, Inaam A. Nakchbandi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 58, Iss , Pp 101058- (2024)
Tumor cells can migrate from a primary cancer and form metastases by localizing to niches within other organs including the bone marrow, where tumor cells may exploit the hematopoietic stem cell niche. The precise composition of the premetastatic and
Externí odkaz:
https://doaj.org/article/7a41e04d0d844ecabbb935af4efe6cc8
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Immune system recognizes invading microbes at both pathogen and antigen levels. Toll-like receptors (TLRs) play a key role in the first-line defense against pathogens. Major functions of TLRs include cytokine and chemokine production. TLRs share comm
Externí odkaz:
https://doaj.org/article/ce97a850bb164120bb6ee1759eecb9e6
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Background Maintaining a tight blood–brain barrier (BBB) is an important prerequisite for the preservation of neurological health, though current evidence suggests it declines with age. While extracellular matrix-integrin interactions play
Externí odkaz:
https://doaj.org/article/5d0b48c365d6408cb41c6c0149a70f6b
Autor:
Yu. Yu. Rakina, N. V. Krakhmal, D. S. Pismenny, A. V. Zavyalov, S. V. Vtorushin, S. G. Afanasyev, M. V. Zavyalova
Publikováno v:
Сибирский онкологический журнал, Vol 22, Iss 2, Pp 93-102 (2023)
Background. Pancreatic cancer is characterized by pronounced invasive growth and a high tendency to lymphogenous and hematogenous metastasis. Molecular mechanisms underlying the epithelial-mesenchymal transition, in particular, changes in the express
Externí odkaz:
https://doaj.org/article/5daee5faa0794537b0d6aff43b278629
Autor:
Fu Jing, Peng Shengkun
Publikováno v:
Open Life Sciences, Vol 18, Iss 1, Pp 91-113 (2023)
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that exhibits aggressive tumor phenotypes, including rapid metastasis and tumor recurrence. Integrins belong to the family of transmembrane glycoproteins involved in regulating cell a
Externí odkaz:
https://doaj.org/article/8bbbc45df95b4ef8a3d25f20d505f4ff
Autor:
Maria Teresa Schettino, Eleonora Petra Preti, Valeria Vietri, Nadia Agrillo, Nicola Iavazzo, Diego Domenico Fasulo, Pasquale De Franciscis, Maria Rosaria Campitiello, Maria Giovanna Vastarella, Gaetano Riemma, Barbara Gardella, Filippo Murina
Publikováno v:
Medicina, Vol 60, Iss 3, p 364 (2024)
Background and Objectives: Available evidence reports the overexpression of β1 integrin in dysplastic rather than normal cervical tissue. We aimed to evaluate the involvement of β1 (CD29) integrin in the progressive pathogenesis of cervical intraep
Externí odkaz:
https://doaj.org/article/7c5431ac8b844d8188adc7491d31e9e6