Zobrazeno 1 - 10
of 275
pro vyhledávání: '"β-arrestin2"'
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Objective Temporomandibular joint osteoarthritis (TMJOA) is a chronic degenerative joint disorder characterized by extracellular matrix degeneration and inflammatory response of condylar cartilage. β-arrestin2 is an important regulator of i
Externí odkaz:
https://doaj.org/article/ade90469ce8f408a8b0b5760b993b9e7
Autor:
Sangita Sutradhar, Hydar Ali
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAllergic asthma has been linked to the activation of mast cells (MCs) by the neuropeptide substance P (SP), but the mechanism underlying this neuroimmune interaction is unknown. Substance P produced from cutaneous nociceptors activates MC
Externí odkaz:
https://doaj.org/article/05484dd38ed54c9eb0840f506c65c3bd
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 781-799 (2024)
Xinting Wang,1,* Jiahui Yang,1,* Cheng Lu,2 Yinqin Hu,1 Zhaohui Xu,1 Qiqi Wan,1 Meng Zhang,1 Tianyun Shi,1 Zhirui Liu,1 Yongming Liu1 1Department of Cardiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medici
Externí odkaz:
https://doaj.org/article/4977a148bb5b4319b662c8c4ff8cf43e
Autor:
Yuhao Zhou, Fei Li, Bangyu Zou, Xiaofeng Zhou, Lianmin Luo, Sicheng Dong, Zhiqing He, Zhixiong Zhang, Liqiong Liao, Hongxing Liu, Chao Cai, Di Gu, Xiaolu Duan
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Purpose To investigate the influence of β-arrestin2 on the docetaxel resistance in castration-resistant prostate cancer (CRPC) and elucidate the underlying molecular mechanisms. Methods PC3 and DU145 cells with stable β-arrestin2 overexpre
Externí odkaz:
https://doaj.org/article/01069a0d2c2b407ba4c607822e9381c5
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115830- (2023)
Thyrotropin-releasing hormone (TRH) is known to activate several cellular signaling pathway, but the activation of the TRH receptor (TRH-R) has not been reported to regulate gene transcription. The aim of this study was to identify phosphosignaling p
Externí odkaz:
https://doaj.org/article/163744d5ecf24ee0af4b6693f3e50865
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 3, Pp 456-461 (2023)
Objective To investigate the regulation and mechanism of Herkinorin preconditioning on NOD-like receptor protein 3 (NLRP3) in brain tissue of transient middle cerebral artery occlusion (tMCAO) rats. Methods Rats were randomly divided into sham operat
Externí odkaz:
https://doaj.org/article/b6b9abbc99aa4707b8da4ace0e666c97
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3395 (2024)
Arrestins are known to be involved not only in the desensitization and internalization of G protein-coupled receptors but also in the G protein-independent activation of mitogen-activated protein (MAP) kinases, such as extracellular signal-regulated
Externí odkaz:
https://doaj.org/article/fac5ea2426944d08bf986590504225bd
Autor:
Yang Liu, Nanshan Song, Hang Yao, Siyuan Jiang, Yueping Wang, Ying Zheng, Yuanzhang Zhou, Jianhua Ding, Gang Hu, Ming Lu
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Major depressive disorder (MDD) is a prevalent and devastating psychiatric illness. Unfortunately, the current therapeutic practice, generally depending on the serotonergic system for drug treatment is unsatisfactory and shows int
Externí odkaz:
https://doaj.org/article/55a35af0ffc947ebb73efd322adade43
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Akademický článek
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