Zobrazeno 1 - 10
of 10 271
pro vyhledávání: '"β-amyloid"'
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 7993-8008 (2024)
Chi-Chen Huang,1 Sheng-Feng Tsai,2,3 Shu-Cheng Liu,4 Mei-Chen Yeh,5 Hao-Chang Hung,5 Chu-Wan Lee,6 Ching-Li Cheng,6 Pei-Ling Hsu,7– 9 Yu-Min Kuo2,3 1Division of Neurosurgery, Department of Surgery, National Cheng Kung University Hospital, College o
Externí odkaz:
https://doaj.org/article/dd07563a26044af284d5fcdb7e35f483
Publikováno v:
Journal of Innate Immunity, Vol 16, Iss 1, Pp 501-512 (2024)
Introduction: Osteoarthritis (OA) is a prevalent chronic joint disorder. It is characterized by an immune response that maintains a low level of inflammation throughout its progression. During OA, cartilage degradation leads to the release of damage-
Externí odkaz:
https://doaj.org/article/152dd123181c4a98bbc3d73f8adaa8d5
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disease that causes cognitive dysfunction in older adults. One of the AD pathological factors, β-Amyloid (Aβ), triggers inflammatory responses and phagocytosis of microglia. C-ty
Externí odkaz:
https://doaj.org/article/8fec39495d024e938bed4c6fc44d369b
Autor:
Richa Arya, Smita Jain, Sarvesh Paliwal, Kirtika Madan, Swapnil Sharma, Achal Mishra, Prashant Tiwari, Sunil Kumar Kadiri
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 14, Iss 9, Pp 369-381 (2024)
Alzheimer’s disease is a neurological disorder marked by the accumulation of amyloid beta (Aβ) aggregates, resulting from mutations in the amyloid precursor protein. The enzyme β-secretase, also known as β-site amyloid precursor protein cleaving
Externí odkaz:
https://doaj.org/article/951eb488d02145528b4cd5f5f3dabbf5
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-48 (2024)
Abstract Alzheimer’s disease (AD) is the most common neurodegenerative disorder, characterized pathologically by extracellular deposition of β-amyloid (Aβ) into senile plaques and intracellular accumulation of hyperphosphorylated tau (pTau) as ne
Externí odkaz:
https://doaj.org/article/7e1c77e3b8ed40e2ae273155ed209e53
Autor:
Oliwia Koszła, Przemysław Sołek
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract The primary challenge in today’s world of neuroscience is the search for new therapeutic possibilities for neurodegenerative disease. Central to these disorders lies among other factors, the aberrant folding, aggregation, and accumulation
Externí odkaz:
https://doaj.org/article/decd79ac91bf42d9af4d437c2b88473e
Autor:
Ji-Won Lee, Kaito Mizuno, Haruhisa Watanabe, In-Hee Lee, Takuya Tsumita, Kyoko Hida, Yasutaka Yawaka, Yoshimasa Kitagawa, Akira Hasebe, Tadahiro Iimura, Sek Won Kong
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Multinucleated microglia have been observed in contexts associated with infection, inflammation, and aging. Though commonly linked to pathological conditions, the larger cell size of multinucleated microglia might enhance their phagocytic fu
Externí odkaz:
https://doaj.org/article/42390726e32e40f7b382cf7f7dcc8d93
Publikováno v:
Journal of Taibah University Medical Sciences, Vol 19, Iss 3, Pp 549-565 (2024)
الملخص: تطور مرض ألزهايمر كنتيجة لتكوين علامتين رئيسيتين، والتي تتضمن تشكيل طفيليات البيتا-أميلويد خارج الخلو وفرط فسفرة بروتين الـ تاو
Externí odkaz:
https://doaj.org/article/7285c341bed94ce79ecdb3672abd03de
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Recent reports suggest that amyloid beta (Aβ) peptides can exhibit prion-like pathogenic properties. Transmission of Aβ peptide and the development of associated pathologies after surgeries with contaminated instruments and intr
Externí odkaz:
https://doaj.org/article/138af1cc6e0145c7ac61284247af3f6e
Autor:
Iram Iqbal, Fatima Saqib, Zobia Mubarak, Muhammad Farhaj Latif, Muqeet Wahid, Bushra Nasir, Hamna Shahzad, Javad Sharifi-Rad, Mohammad S. Mubarak
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-20 (2024)
Abstract Alzheimer's disease (AD) is a diverse disease with a complex pathophysiology. The presence of extracellular β-amyloid deposition as neuritic plaques and intracellular accumulation of hyper-phosphorylated tau as neurofibrillary tangles remai
Externí odkaz:
https://doaj.org/article/f02291430fa24c19b79083fa28bcc496