Zobrazeno 1 - 10
of 30 430
pro vyhledávání: '"β-Catenin"'
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background The established association between Alzheimer's disease (AD) and compromised neural regeneration is well-documented. In addition to the mitigation of apoptosis in neural stem cells (NSCs), the induction of neurogenesis has been pr
Externí odkaz:
https://doaj.org/article/509fe601a6e7470b9ea8a790c186aa8e
Autor:
Hyun Geun Oh, Minyoung Jung, Seon-Yeong Jeong, Jimin Kim, Sang‑Deok Han, Hongduk Kim, Seulki Lee, Yejin Lee, Haedeun You, Somi Park, Eun A. Kim, Tae Min Kim, Soo Kim
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Androgenetic alopecia (AGA) is a common form of hair loss. Androgens, such as testosterone and dihydrotestosterone, are the main causes of AGA. Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) can reduce AGA
Externí odkaz:
https://doaj.org/article/5bc4d1a9095d4a4f91d0d9afe94d13b0
Publikováno v:
Nutrition & Metabolism, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background Breast cancer is the most diagnosed cancer in women. Its pathogenesis includes several pathways in cancer proliferation, apoptosis, and metastasis. Some clinical data have indicated the association between coffee consumption and d
Externí odkaz:
https://doaj.org/article/f9e33028a2eb4691ba67e8a61539e4a9
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Age-related osteoporosis is a prevalent bone metabolic disorder distinguished by an aberration in the equilibrium between bone formation and resorption. The reduction in the stemness of Bone Marrow Mesenchymal Stem Cells (BMSCs) plays a pivo
Externí odkaz:
https://doaj.org/article/3efcdbf11a2b4bc281227c8647abf671
Autor:
Mengyi Yan, Xiayun Chen, Xiaotong Li, Qianqian Liu, Baixue Yu, Yi Cen, Wei Zhang, Yibin Liu, Xinxuan Li, Ying Chen, Tao Wang, Shiying Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4118-4133 (2024)
The immunosuppressive phenotype of tumor cells extensively attenuates the immune activation effects of traditional treatments. In this work, a transferrin receptor (TfR) targeted immunostimulant (PTI) is fabricated for photodynamic immunotherapy agai
Externí odkaz:
https://doaj.org/article/e82264c1b8c34b5596ecc6997c5f01a8
Autor:
Yalan Li, Xiaoyue Chen, Yiqing Xiong, Xueqiang Xu, Caidie Xie, Min Min, Dongmei Liang, Cheng Chen, Huijuan Mao
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background The prevalence of vascular calcification (VC) in chronic kidney disease (CKD) patients remains substantial, but currently, there are no effective pharmaceutical therapies available. BRCA1/BRCA2-containing complex subunit 36 (BRCC3
Externí odkaz:
https://doaj.org/article/c02d71d0f79247c9a7b30b57fc94fc2a
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Clinical trials and studies have implicated that E3 ubiquitin ligase BTBD3 (BTB Domain Containing 3) is a cancer-associated gene. However, the role and underlying mechanism of BTBD3 in colorectal cancer (CRC) is not fully understood yet. Her
Externí odkaz:
https://doaj.org/article/8143ce00dfa740c6aa6598e2fee6d129
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 9227-9253 (2024)
Guoqiang Xu,1,2,* Xiaona Song,2,* Xiaotang Wang,1,2,* Rui Xue,1,2 Xiaoru Yan,1,2 Litao Qin,1,2 Xiaoqi Chang,1,2 Jiping Gao,1 Zhaoyang Chen,1 Guohua Song1 1Laboratory Animal Center Shanxi Key Laboratory of Experimental Animal Science and H
Externí odkaz:
https://doaj.org/article/8e03627a33cc4ffb8aa300eb947ad717
Autor:
Jonathan M Alexander, Leeanne Vazquez-Ramirez, Crystal Lin, Pantelis Antonoudiou, Jamie Maguire, Florence Wagner, Michele H Jacob
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2109-2131 (2024)
Abstract CTNNB1 syndrome is a rare monogenetic disorder caused by CTNNB1 de novo pathogenic heterozygous loss-of-function variants that result in cognitive and motor disabilities. Treatment is currently lacking; our study addresses this critical need
Externí odkaz:
https://doaj.org/article/19f1b69be0b84f4cb9a069254536ee34