Zobrazeno 1 - 10
of 1 510
pro vyhledávání: '"β-Arrestin"'
Publikováno v:
Cells, Vol 13, Iss 20, p 1674 (2024)
The prolonged overstimulation of β-adrenergic receptors (β-ARs), a member of the G protein-coupled receptor (GPCR) family, causes abnormalities in the density and functionality of the receptor and contributes to cardiac dysfunctions, leading to the
Externí odkaz:
https://doaj.org/article/8c0bb5345dce497891001840fc9669cd
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/026e4b553f4144019a1b103dda3cce3f
Autor:
Lan Phuong Nguyen, Minyeong Cho, Thai Uy Nguyen, Hee-Kyung Park, Huong Thi Nguyen, Kateryna Mykhailova, Sunghoon Hurh, Hong-Rae Kim, Jae Young Seong, Cheol Soon Lee, Byung-Joo Ham, Jong-Ik Hwang
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Background Tachykinins and their cognate receptors, neurokinin receptors (NKs) including NK1, NK2, and NK3 play vital roles in regulating various physiological processes including neurotransmission, nociception, inflammation, smooth muscle c
Externí odkaz:
https://doaj.org/article/307d7b190b1740099026f1f1d0b3fcd4
Autor:
Alexander O. Shpakov
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 9, p 313 (2024)
Luteinizing hormone (LH) and human chorionic gonadotropin (CG), like follicle-stimulating hormone, are the most important regulators of the reproductive system. They exert their effect on the cell through the LH/CG receptor (LHCGR), which belongs to
Externí odkaz:
https://doaj.org/article/71575645fffd43eab35407db513ad8cd
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
There is now evidence from multiple Phase II clinical trials that psychedelic drugs can exert long-lasting anxiolytic, anti-depressant, and anti-drug abuse (nicotine and ethanol) effects in patients. Despite these benefits, the hallucinogenic actions
Externí odkaz:
https://doaj.org/article/59f60518aad045a08b4c3d8cae89d31e
Autor:
Emilio Y. Lucero‐Garcia Rojas, Arfaxad Reyes‐Alcaraz, Kehe Ruan, Bradley K. McConnell, Richard A. Bond
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 12, Pp 758-774 (2022)
Abstract The β2AR is a prototypical G protein‐coupled receptor (GPCR) known to orchestrate different cellular responses by the stimulation of specific signaling pathways. The best‐established signaling pathways for the β2AR are the canonical Gs
Externí odkaz:
https://doaj.org/article/f1ee986d5c6b434dbf21a6fe72535b42
Autor:
Dominik Straszak, Sylwia Woźniak, Agata Siwek, Monika Głuch-Lutwin, Marcin Kołaczkowski, Aldona Pietrzak, Bartłomiej Drop, Dariusz Matosiuk
Publikováno v:
Molecules, Vol 29, Iss 3, p 571 (2024)
μ-opioid receptor ligands such as morphine and fentanyl are the most known and potent painkillers. However, the severe side effects seen with their use significantly limit their widespread use. The continuous broadening of knowledge about the proper
Externí odkaz:
https://doaj.org/article/320eb04a4c514654807a191ca7115d2e
Autor:
Eun Young Kim, Stuart E. Dryer
Publikováno v:
Cells, Vol 13, Iss 2, p 172 (2024)
The soluble urokinase plasminogen activator receptor (suPAR) has been implicated in a wide range of pathological conditions including primary nephrotic syndromes and acute kidney injuries. suPAR can trigger transduction cascades in podocytes by outsi
Externí odkaz:
https://doaj.org/article/85a225fda41d438d8ae80754ccf7ad9c
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