Zobrazeno 1 - 10
of 613
pro vyhledávání: '"β amyloid protein"'
Publikováno v:
Smart Molecules, Vol 2, Iss 2, Pp n/a-n/a (2024)
Abstract Metastable endoperoxides with beta‐amyloid fibrils targeting benzothiazole moieties were designed and synthesized. Singlet oxygen released from these endoperoxides by thermal cycloreversion reaction was shown to cause significant structura
Externí odkaz:
https://doaj.org/article/df0c3f1e99b543af903fcfb88712add7
Autor:
Zhongsheng CHEN, Zhangcheng FEI, Renjun PEI, Congchao QIAO, Zongkui WANG, Shengliang YE, Li MA, Rong ZHANG, Changqing LI, Xi DU, Haijun CAO
Publikováno v:
Zhongguo shuxue zazhi, Vol 36, Iss 5, Pp 396-403 (2023)
Objective To explore the risk of Alzheimer′s disease (AD) transmitted by blood transfusion. Methods There were 10 APP/PS1 mice of 3, 6 and 9 months old, half female and half male, and the cognitive and behavioral abilities of C57 mice of the same a
Externí odkaz:
https://doaj.org/article/4aeb5581fb5b4248b4ac59cd62b5fece
Autor:
Xiaotong Wang, Rui Zhou, Xiaqin Sun, Jun Li, Jinxin Wang, Weihua Yue, Lifang Wang, Hesheng Liu, Yigong Shi, Dai Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract A hallmark of Alzheimer's disease (AD) is the senile plaque, which contains β‐amyloid peptides (Aβ). Ganglioside GM1 is the most common brain ganglioside. However, the mechanism of GM1 in modulating Aβ processing is rarely known. Aβ le
Externí odkaz:
https://doaj.org/article/93404aa7e3f34b29b562184fa4160ed6
Publikováno v:
Shiyan dongwu yu bijiao yixue, Vol 42, Iss 5, Pp 432-439 (2022)
Alzheimer's disease is a common neurodegenerative disease characterized by progressive memory loss and overall cognitive decline. Two typical pathological features are senile plaques and neurofibrillary tangles detected in the brain, which consist of
Externí odkaz:
https://doaj.org/article/5df002166bf345c993364393d7e9235c
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Alzheimer’s disease (AD) is the most common chronic neurodegenerative disease worldwide. It causes cognitive dysfunction, such as aphasia and agnosia, and mental symptoms, such as behavioral abnormalities; all of which place a significant psycholog
Externí odkaz:
https://doaj.org/article/06078da0bebf45d0ad5cd8bed9e3ddbd
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Ming Zhong, Huiqiang Wang, Haiyan Yan, Shuo Wu, Kun Wang, Lu Yang, Boming Cui, Mengyuan Wu, Yuhuan Li
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract Background β-Amyloid (Aβ) protein is a pivotal pathogenetic factor in Alzheimer’s disease (AD). However, increasing evidence suggests that the brain has to continuously produce excessive Aβ to efficaciously prevent pathogenic micro-orga
Externí odkaz:
https://doaj.org/article/52612c4bad924fce92d694731d517550
Publikováno v:
Zhenduanxue lilun yu shijian, Vol 21, Iss 01, Pp 86-89 (2022)
Alzheimer′s disease (AD) and cerebral amyloid angiopathy (CAA) have close clinical and pathological relationships. In this paper, a 54-year male patients with AD and CAA is reported. AD is diagnosed according to A/T/N biomarker framework, and the c
Externí odkaz:
https://doaj.org/article/509e574aa49745cfa6dfe518dd143b34