Zobrazeno 1 - 10
of 57
pro vyhledávání: '"αvβ3-Integrin"'
Autor:
Yanshu Wang, Huanhuan Liu, Defan Yao, Jinning Li, Shuyan Yang, Caiyuan Zhang, Weibo Chen, Dengbin Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Purpose To develop a novel fluorine-18 (18F)-labeled arginine–glycine–aspartic acid (RGD)-coupled ultra-small iron oxide nanoparticle (USPIO) (hereafter, referred to as 18F-RGD@USPIO) and conduct an in-depth investigation to monitor the
Externí odkaz:
https://doaj.org/article/259980b053844e819f70132ae33b63ab
Autor:
Yin Song, Wei Li, Shuyan Meng, Wei Zhou, Bo Su, Liang Tang, Yinmin Zhao, Xiaoyan Wu, Dazhi Yin, Mingxia Fan, Caicun Zhou
Publikováno v:
Nanoscale Research Letters, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract Enhanced MRI (magnetic resonance imaging) plays a vital role in the early detection of tumor but with low specificity. Molecular imaging of angiogenesis could efficiently deliver contrast agents to the tumor site by specific targeted carrier
Externí odkaz:
https://doaj.org/article/11d5e9f915e448c0bd367b453f38d396
Akademický článek
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Publikováno v:
Bioengineered, Vol 13, Iss 2, Pp 4557-4572 (2022)
Integrins play an important role in multiple stages of tumor progression and metastasis. Previous studies have shown synergistic effects of combined αvβ6-integrin and αvβ8-integrin inhibitors with immunotherapy. However, the role of αvβ3-integr
Autor:
Cajetan Immanuel Lang, Piet Döring, Ralf Gäbel, Praveen Vasudevan, Heiko Lemcke, Paula Müller, Jan Stenzel, Tobias Lindner, Markus Joksch, Jens Kurth, Carina Bergner, Hans-Jürgen Wester, Hüseyin Ince, Gustav Steinhoff, Brigitte Vollmar, Robert David, Bernd Joachim Krause
Publikováno v:
Cells, Vol 9, Iss 6, p 1358 (2020)
Angiogenesis plays a central role in the healing process following acute myocardial infarction. The PET tracer [68Ga]-NODAGA-RGD, which is a ligand for the αvβ3 integrin, has been investigated for imaging angiogenesis in the process of healing myoc
Externí odkaz:
https://doaj.org/article/e20721c4c2414f1399df8a49cdaa5c18
Akademický článek
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Autor:
Catia Barboni, Anna Zaghini, Valerio Leoni, Tatiana Gianni, Gabriella Campadelli-Fiume, Andrea Vannini, Paolo Malatesta, Mara Sanapo
Publikováno v:
Proceedings of the National Academy of Sciences. 116:20141-20150
Tumors utilize a number of effective strategies, including the programmed death 1/PD ligand 1 (PD-1/PD-L1) axis, to evade immune-mediated control of their growth. PD-L1 expression is mainly induced by IFN receptor signaling or constitutively induced.
Akademický článek
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Autor:
Brigitte Vollmar, Tobias Lindner, Carina Bergner, Jens Kurth, Paula Müller, Heiko Lemcke, Jan Stenzel, Bernd J. Krause, Markus Joksch, Robert David, Cajetan Immanuel Lang, Hans-Jürgen Wester, Hüseyin Ince, Gustav Steinhoff, R Gäbel, Praveen Vasudevan, Piet Döring
Publikováno v:
Cells
Volume 9
Issue 6
Cells, Vol 9, Iss 1358, p 1358 (2020)
Volume 9
Issue 6
Cells, Vol 9, Iss 1358, p 1358 (2020)
Angiogenesis plays a central role in the healing process following acute myocardial infarction. The PET tracer [68Ga]-NODAGA-RGD, which is a ligand for the &alpha
v&beta
3 integrin, has been investigated for imaging angiogenesis in the proc
v&beta
3 integrin, has been investigated for imaging angiogenesis in the proc
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 127, Iss, Pp 110179-(2020)
We have designed 2-domain anticancer peptides with RGD-based KLAK bi-functional short motifs (linear and cyclic analogues). RGD tripeptide acts as tumor blood vessel ‘homing’ motif while KLAK tetrapeptide internalized in mitochondria and causes c