Zobrazeno 1 - 10
of 2 169
pro vyhledávání: '"αVβ3"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 8237-8251 (2024)
Xuefeng Hou,1– 4,* Qi Chen,1,* Ying Fang,5 Li Zhang,1 Shuoheng Huang,1 Minjie Xu,1 Yaning Ren,1 Zhansen Shi,1 Yan Wei,1 Lihua Li1– 4 1School of Pharmacy, Wannan Medical College, Wuhu, Anhui Province, People’s Republic of China; 2Anhui P
Externí odkaz:
https://doaj.org/article/fd363505dd494a5e8a687d1b6949ac39
Publikováno v:
Journal of Experimental Nanoscience, Vol 19, Iss 1 (2024)
This study investigated whether 10058-F4, a small molecule inhibitor of the c-Myc gene, could play a corresponding inhibitory role in the vascular proliferation process. The efficacy and targeting ability of the synthesised drug-loaded nanoparticles
Externí odkaz:
https://doaj.org/article/eebcca1a247d4d1c8583f519d19883d8
Autor:
Mimi Zhou, Yali Feng, Xiaoli Zhang, Jianguo Chen, Naijuan Yao, Shan Fu, Tianzhi Ni, Yi Chen, Fei Xie, Sahasrabda Roy, Jinfeng Liu, Yuan Yang, Yingli He, Yingren Zhao, Nan Yang
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Approximately two-thirds of hepatocellular carcinoma (HCC) is considered a “cold tumor” characterized by few tumor-infiltrating T cells and an abundance of immunosuppressive cells. Cilengitide, an integrin αvβ3 inhibitor, has failed in clinical
Externí odkaz:
https://doaj.org/article/065d3b3d163b4f5ab57e81638702dbe7
Autor:
Xiangwu Geng, Yifan Tang, Changjiang Gu, Junkai Zeng, Yin Zhao, Quanwei Zhou, Lianshun Jia, Shengyuan Zhou, Xiongsheng Chen
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Ossification of the posterior longitudinal ligament (OPLL), an emerging heterotopic ossification disease, causes spinal cord compression, resulting in motor and sensory dysfunction. The etiology of OPLL remains unclear but may inv
Externí odkaz:
https://doaj.org/article/95bc5135249a4d8dae508fe4713e2c24
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Cardiac remodeling after myocardial infarction is one of the key factors affecting patient prognosis. Myocardial fibrosis is an important pathological link of adverse ventricular remodeling after myocardial infarction, and early fibrosis is reversibl
Externí odkaz:
https://doaj.org/article/d2f8cadd3c0f424790a74714607b8ece
Publikováno v:
iRADIOLOGY, Vol 2, Iss 2, Pp 128-155 (2024)
Abstract Optimal therapeutic and diagnostic efficacy is essential for healthcare's global mission of advancing oncologic drug development. Accurate diagnosis and detection are crucial prerequisites for effective risk stratification and personalized p
Externí odkaz:
https://doaj.org/article/581ec3af255d4077ac1263947fae3b69
Autor:
Ayijiang Taledaohan, Maer Maer Tuohan, Renbo Jia, Kai Wang, Liujia Chan, Yijiang Jia, Feng Wang, Yuji Wang
Publikováno v:
Antioxidants, Vol 13, Iss 11, p 1339 (2024)
Cerebral ischemia–reperfusion injury significantly contributes to global morbidity and mortality. Loganin is a natural product with various neuroprotective effects; however, it lacks targeted specificity for particular cells or receptors, which may
Externí odkaz:
https://doaj.org/article/ea08199afafe4bafab79501a77f40191
Publikováno v:
Pharmaceuticals, Vol 17, Iss 11, p 1556 (2024)
Integrins, an important superfamily of cell adhesion receptors, play an essential role in cancer progression, metastasis, and angiogenesis, establishing them as prime targets for both diagnostic and therapeutic applications. Despite their significant
Externí odkaz:
https://doaj.org/article/452104bc430f447698ecf1b7a7c97067
Autor:
Zhengpeng Wan, Shun Zhang, Amy X. Zhong, Liling Xu, Mark F. Coughlin, Georgios Pavlou, Sarah E. Shelton, Huu Tuan Nguyen, Satomi Hirose, Seunggyu Kim, Marie A. Floryan, David A. Barbie, F. Stephen Hodi, Roger D. Kamm
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Endothelial programmed death‐ligand 1 (PD‐L1) expression is higher in tumors than in normal tissues. Also, tumoral vasculatures tend to be leakier than normal vessels leading to a higher trans‐endothelial or transmural fluid flow. Howe
Externí odkaz:
https://doaj.org/article/e0b6d2b3cd9a4d6185b943c5ce795bda
Autor:
Chung-Che Tsai, Yung-Ning Yang, Kuan Wang, Yu-Chun E. Chen, Yi-Fong Chen, Jen-Chang Yang, Zi-Lin Li, Haw-Ming Huang, Jens Z. Pedersen, Sandra Incerpi, Sheng-Yang Lee, Hung-Yun Lin, Jaqueline Whang-Peng
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e34006- (2024)
Progesterone (P4) plays a pivotal role in regulating the cancer progression of various types, including breast cancer, primarily through its interaction with the P4 receptor (PR). In PR-negative breast cancer cells, P4 appears to function in mediatin
Externí odkaz:
https://doaj.org/article/7e3013834876452d9bf07b1276ce3013