Zobrazeno 1 - 10
of 248
pro vyhledávání: '"α4β1"'
Autor:
Aksak, Tiinçe a, ⁎, 1, Askin, Ali b, Polat, Sait c, Ürünsak, İbrahim Ferhat d, Karaoğlan, Özdem c
Publikováno v:
In Journal of Reproductive Immunology February 2025 167
Autor:
Razieh Rezaeianpour, Ramin Lotfi, Seyed Hamidreza Mortazavi, Ali Gorgin Karaji, Alireza Rezaiemanesh, Farhad Salari
Publikováno v:
Acta Medica Iranica, Vol 61, Iss 8 (2024)
Allergic rhinitis (AR) is a chronic inflammatory disease involving the nasal mucosa. Leukocytes recruitment to the inflammation sites is controlled by chemokines, cytokines, and adhesion molecules. Retinoic acid (RA), a vitamin A metabolite, plays an
Externí odkaz:
https://doaj.org/article/2efe1b76e33e4d55b51c1b5b06a49af3
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 316 (2024)
Integrins are heterodimeric cell-surface receptors that regulate cell–cell adhesion and cellular functions through bidirectional signaling. On the other hand, anomalous trafficking of integrins is also implicated in severe pathologies as cancer, th
Externí odkaz:
https://doaj.org/article/de44bb42e1ef477d98086360e5f0f973
Autor:
Yi Hsing Chen, Malihe Eskandarpour, Xiaozhe Zhang, Grazyna Galatowicz, John Greenwood, Sue Lightman, Virginia Calder
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background The integrin VLA-4 (α4β1) plays an important role in leukocyte trafficking. This study investigated the efficacy of a novel topical α4β1 integrin inhibitor (GW559090, GW) in a mouse model for non-infectious posterior uveitis (
Externí odkaz:
https://doaj.org/article/9de152e6d08040b697c82aa3893728fb
Publikováno v:
eLife, Vol 10 (2021)
Integrin conformational ensembles contain two low-affinity states, bent-closed and extended-closed, and an active, high-affinity, extended-open state. It is widely thought that integrins must be activated before they bind ligand; however, one model h
Externí odkaz:
https://doaj.org/article/ede5e2f8cffd442a9ea94f51a327fbff
Autor:
Hai-Yan Lou, Hai-Peng Yan, Long-Gui Yang, Jiang-hua Fan, William C. Cho, Zheng-hui Xiao, Shuang-Jie Li
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Bacterial and viral infection is a common cause of pneumonia, respiratory failure, and even acute respiratory distress syndrome. Increasing evidence indicates that red blood cells (RBCs) may contribute to immune response and inflammation. However, th
Externí odkaz:
https://doaj.org/article/9f4f819240c0479787557b0dfa47b8c1
Autor:
Alexandru Filippi, Alina Constantin, Nicoleta Alexandru, Cristina Ana Mocanu, Mihaela Loredana Vlad, Ioana Madalina Fenyo, Agneta Simionescu, Dan Teodor Simionescu, Ileana Manduteanu, Adriana Georgescu
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1077 (2022)
The number and function of endothelial progenitor cells (EPCs) are reduced in diabetes, contributing to deteriorated vascular repair and the occurrence of cardiovascular complications. Here, we present the results of treating early diabetic dyslipide
Externí odkaz:
https://doaj.org/article/43fde9ec37ff44a99e1ccb6c12d7926f
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The non-selective mechanosensitive ion channel PIEZO1 controls erythrocyte volume homeostasis. Different missense gain-of-function mutations in PIEZO1 gene have been identified that cause Hereditary Xerocytosis (HX), a rare autosomal dominant haemoly
Externí odkaz:
https://doaj.org/article/af06a48afd7b4a559d8f71cf235b7fb7