Zobrazeno 1 - 10
of 228
pro vyhledávání: '"α2-Antiplasmin"'
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 2, Pp 217-232 (2024)
Introduction. Various compounds of mushroom extracts are of interest as a source of new active pharmaceutical substances with antithrombotic activity.Aim. The aim of the work is to determine the potential antithrombotic activity in vitro of aqueous e
Externí odkaz:
https://doaj.org/article/bbce1cb4b1e9463bbf05c248f04e6baf
Akademický článek
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Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
The superfamily of serine protease inhibitors (SERPINs) are a class of inhibitors that utilise a dynamic conformational change to trap and inhibit their target enzymes. Their powerful nature lends itself well to regulation of complex physiological en
Externí odkaz:
https://doaj.org/article/bff0cfa9e34d45da97b1fd213619d4ec
Autor:
Basmah Alsayejh, Noppadol Kietsiriroje, Mansour Almutairi, Katie Simmons, Nikoletta Pechlivani, Sreenivasan Ponnambalam, Ramzi A. Ajjan
Publikováno v:
TH Open, Vol 06, Iss 04, Pp e396-e407 (2022)
Abstract The vascular obstructive thrombus is composed of a mesh of fibrin fibers with blood cells trapped in these networks. Enhanced fibrin clot formation and/or suppression of fibrinolysis are associated with an increased risk of vascular occlusi
Externí odkaz:
https://doaj.org/article/c4ed8a57ea634e09829e465ce1a35a1e
Autor:
Eri Kawashita, Keiichi Ishihara, Haruko Miyaji, Yu Tanishima, Akiko Kiriyama, Osamu Matsuo, Satoshi Akiba
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract α2-Antiplasmin (α2AP), a principal physiological plasmin inhibitor, is mainly produced by the liver and kidneys, but it is also expressed in several parts of the brain, including the hippocampus and cerebral cortex. Our previous study demo
Externí odkaz:
https://doaj.org/article/2f860ad92f6d4b0db1a04621638e0e22
Publikováno v:
FEBS Open Bio, Vol 9, Iss 7, Pp 1259-1269 (2019)
Streptokinase (SK) is a plasminogen activator which converts inactive plasminogen (Pg) to active plasmin (Pm), which cleaves fibrin clots. SK secreted by groups A, C, and G Streptococcus (SKA/SKC/SKG) is composed of three domains: SKα, SKβ and SKγ
Externí odkaz:
https://doaj.org/article/242b3dfc29f04d59818a9f18c5edac04
Autor:
Yosuke Kanno, En Shu
Publikováno v:
Life, Vol 12, Iss 3, p 396 (2022)
Systemic sclerosis is a connective tissue disease of unknown origin that is characterized by immune system abnormalities, vascular damage, and extensive fibrosis of the skin and visceral organs. α2-antiplasmin is known to be the main plasmin inhibit
Externí odkaz:
https://doaj.org/article/1a2fe886c8df4147b2514d8985a4a36f
Akademický článek
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Publikováno v:
Micromachines, Vol 13, Iss 1, p 55 (2021)
We used the research quartz crystal microbalance (RQCM) to monitor regulatory effects of plasmin and trypsin in the presence of their inhibitor α2-antiplasmin. The gold surface of quartz crystals was modified with a β-casein layer that served as a
Externí odkaz:
https://doaj.org/article/4b9644fe2eae4e30b32c654dc125a0e2
Publikováno v:
Life, Vol 11, Iss 12, p 1340 (2021)
Fibrinogen synthesis is stimulated by proinflammatory triggers and depends on α-, β- and γ-fibrinogen (FGA, FGB, FGG) genotypes. Constellations of fibrinogen, factor XIII A-subunit (F13A) and α2-antiplasmin (A2AP) genotypes predisposing for dense
Externí odkaz:
https://doaj.org/article/f2e045f346754b9a8f192d21a56ca774