Zobrazeno 1 - 10
of 13
pro vyhledávání: '"α2 6 sialyltransferase"'
Publikováno v:
KSBB Journal. 32:193-198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abf3f3b458e01dffc17621c620b68c06
https://doi.org/10.7841/ksbbj.2017.32.3.193
https://doi.org/10.7841/ksbbj.2017.32.3.193
Autor:
Christopher J. Gray, Say-Kong Ng, Pauline M. Rudd, Kun Huang, Sabine L. Flitsch, Matthew S F Choo, Terry Nguyen-Khuong, Wen-Qin Tang, Jien-Nee Tai, Andrea Marchesi, Dawn Leong, Peter Both, Edward Pallister
Publikováno v:
Pallister, E G, Choo, M S F, Tai, J, Leong, D S Z, Tang, W, Ng, S, Huang, K, Marchesi, A, Both, P, Gray, C, Rudd, P M, Flitsch, S L & Nguyen-khuong, T 2019, ' Exploiting the Disialyl Galactose Activity of α2,6-Sialyltransferase from Photobacterium damselae To Generate a Highly Sialylated Recombinant α-1-Antitrypsin ', Biochemistry . https://doi.org/10.1021/acs.biochem.9b00563
Sialic acids are sugars present in many animal glycoproteins and are of particular interest in biopharmaceuticals, where a lack of sialylation can reduce bioactivity. Here, we describe how α-2,6-sialyltransferase from Photobacterium damselae can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042dc84e9b3d4e9cfcb7677cdfd80503
https://pure.manchester.ac.uk/ws/files/140427922/Updated_mauscript_biochemistry_Edward_Pallitser_2nd_revision_manu2.pdf
https://pure.manchester.ac.uk/ws/files/140427922/Updated_mauscript_biochemistry_Edward_Pallitser_2nd_revision_manu2.pdf
Autor:
Shinobu Kitazume
Publikováno v:
Trends in Glycoscience and Glycotechnology. 15:129-137
アルツハイマー病 (AD) においては、多量のアミロイドベータペプチド (Aβ) から構成されるアミロイド斑が脳内に蓄積することが、大きな特色とされている。BACE1プロテアーゼは、前駆体
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7920ffc8c8934be622826f57f7c9dd46
https://doi.org/10.4052/tigg.15.129
https://doi.org/10.4052/tigg.15.129
Autor:
Hitoshi Suzuki, Milada Horynová, Matthew B. Renfrow, Kazuo Takahashi, Tyler J. Stewart, Alena Vrablikova, Jan Novak, Lydie Czernekova, Milan Raska, Bruce A. Julian, Koshi Yamada
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 30(2)
Galactose-deficient O-glycans in the hinge region (HR) of immunoglobulin A1 (IgA1) play a key role in the pathogenesis of IgA nephropathy (IgAN). O-Glycans of circulatory IgA1 consist of N-acetylgalactosamine (GalNAc) with a β1,3-linked galactose; b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afa5c9348a00ed897f05448d6fca9e3
https://pubmed.ncbi.nlm.nih.gov/25281698
https://pubmed.ncbi.nlm.nih.gov/25281698
Publikováno v:
FEBS Letters. 409:347-350
Treatment of human colorectal carcinoma cells HT29 with specific antisense oligodeoxynucleotides led to a decreased Gal beta1,4GlcNAc alpha2,6 sialyltransferase activity on the level of protein expression as well as on the mRNA level. Antisense treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431add2fd741100b7df959f7d177fb80
https://doi.org/10.1016/s0014-5793(97)00543-7
https://doi.org/10.1016/s0014-5793(97)00543-7
Autor:
Reinhard Brossmer, Paraskevi Mirelis
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:2809-2814
Chemo-enzymatic synthesis afforded a series of CMP-activated sialic acids carrying a photoreactive group at C-9 or C-5, and in part a radiolabel as well. They were found to be accepted by α2,6-sialyltransferase. - Differing amino group reactivity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::605d25cfd9021a7c75bfc264f149b8de
https://doi.org/10.1016/0960-894x(95)00491-b
https://doi.org/10.1016/0960-894x(95)00491-b
Autor:
Paraskevi Mirelis, Reinhard Brossmer
Publikováno v:
ChemInform. 27
Chemo-enzymatic synthesis afforded a series of CMP-activated sialic acids carrying a photoreactive group at C-9 or C-5, and in part a radiolabel as well. They were found to be accepted by α2,6-sialyltransferase. - Differing amino group reactivity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b404d658319d45138fdad16fb1cdecb
https://doi.org/10.1002/chin.199614258
https://doi.org/10.1002/chin.199614258
Publikováno v:
Scandinavian journal of immunology. 69(2)
It is known that aberrant sialylation of IgA1 is involved in the pathogenesis of IgA nephropathy (IgAN). We hypothesize that aberrant sialylation of serum IgA1 may result from changes in the activity of alpha2,6-sialyltransferase (alpha2,6-ST) or exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b877f360082747435b0b81e62b7d62
https://pubmed.ncbi.nlm.nih.gov/19170967
https://pubmed.ncbi.nlm.nih.gov/19170967
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 8(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa31a2f185b509179a2a33a7c11088a2
https://pubmed.ncbi.nlm.nih.gov/9096124
https://pubmed.ncbi.nlm.nih.gov/9096124
Publikováno v:
Animal Cell Technology ISBN: 9789401062732
We have characterized two BHK cell lines (BHK-21B and BHK-21A) with different glycosylation properties. N-glycans synthesized by BHK-21B cells contain the typical N-acetyllactosamine motif (Gal(βl-4)GlcNAc-R) whereas BHK-21 A cells bear to a high am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09e6e1147feb2e132bf7a6eb6527aaff
https://doi.org/10.1007/978-94-011-5404-8_76
https://doi.org/10.1007/978-94-011-5404-8_76