Zobrazeno 1 - 10
of 805
pro vyhledávání: '"α1 antitrypsin"'
Publikováno v:
International Journal of COPD, Vol Volume 16, Pp 2617-2630 (2021)
Cristina Martinez-González,1 Ignacio Blanco,2 Isidro Diego,3 Patricia Bueno,4 Marc Miravitlles5 1Pulmonology Department, University Central Hospital of Asturias, Universidad de Oviedo, Instituto de Investigación del Principado de Asturias (ISPA), O
Externí odkaz:
https://doaj.org/article/32b558f38c994bc4a591029d51b332f4
Akademický článek
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Autor:
Marie Fisk, Joseph Cheriyan, Divya Mohan, Carmel M. McEniery, Julia Forman, John R. Cockcroft, James H. F. Rudd, Ruth Tal-Singer, Nicholas S. Hopkinson, Michael I. Polkey, Ian B. Wilkinson
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Chronic obstructive pulmonary disease (COPD) is a complex inflammatory condition in which an important extra-pulmonary manifestation is cardiovascular disease. We hypothesized that COPD patients would have increased aortic inflamm
Externí odkaz:
https://doaj.org/article/40d12aa2a44e4520acd99f76123fdfd9
Publikováno v:
Balkan Journal of Medical Genetics, Vol 19, Iss 2, Pp 35-44 (2016)
Hepatitis C virus (HCV) infection represents a serious health problem. The –174 G/C mutation in the pro inflammatory cytokine interleukin-6 (IL-6) is associated with developing liver diseases. Likewise, the S and Z mutations in the serine protease
Externí odkaz:
https://doaj.org/article/92029a068eee46699a7ebd76a342852e
Autor:
Tomoyuki Nakagiri, Fabio Ius, Ann-Kathrin Knöfel, Tobias Goecke, Patrick Zardo, Tobias Welte, Sabine Wrenger, Veronika Grau, Kokilavani Sivaraman, Axel Haverich, Sabina Janciauskiene
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
Respiratory Research
Respiratory Research
Background α1-Antitrypsin (AAT) is an acute phase glycoprotein, a multifunctional protein with proteinase inhibitory, anti-inflammatory and cytoprotective properties. Both preclinical and clinical experiences show that the therapy with plasma purifi
Autor:
Samuel L. James, Jonathan S. T. Woodhead, Troy L. Merry, Stewart W. C. Masson, Randall F. D'Souza, Christopher P. Hedges, Caitlin MacRae
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 321:E560-E570
Neutrophils accumulate in insulin-sensitive tissues during obesity and may play a role in impairing insulin sensitivity. The major serine protease expressed by neutrophils is neutrophil elastase (NE), which is inhibited endogenously by α1-antitrypsi
Autor:
I. V. Psareva, Yu.M. Stepanov
Publikováno v:
GASTROENTEROLOGY. 51:56-63
Хронічні запальні захворювання кишечника, а саме неспецифічний виразковий коліт та хвороба Крона, привертають увагу як лікарів, так і н
Autor:
Friedrich Kueppers, Farouk Dako, Yogesh Sean Gupta, Alexandra Mulvenna, Huaqing Zhao, Scott A. Simpson
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 5, Iss 3, Pp 590-595 (2021)
Objective To investigate the relationship between α1-antitrypsin deficiency (AATD), a disorder resulting in protease activity imbalances, and the risk of ascending aortic aneurysm. Methods In this single-center study, from August 1, 2018, to Februar
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 11, Iss 3, Pp BC09-BC12 (2017)
Introduction: Pre-eclampsia (PE) is a common maternal syndrome characterized by severe systemic inflammatory response including neutrophil activation leading to uncontrolled activity of elastase. The excessive activity of elastase would lead to d
Externí odkaz:
https://doaj.org/article/bbb74b496c894784a4d56eb62be12566
Publikováno v:
Bulletin of the Korean Chemical Society. 42:900-906