Zobrazeno 1 - 10
of 56
pro vyhledávání: '"α-synuclein aggregation and spreading"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Cholestanol accelerates α-synuclein aggregation and spreading by activating asparagine endopeptidase
Autor:
Ting Yu, Shuke Nie, Lihong Bu, Miao Liu, Juanfeng He, Xuan Niu, Hongyan Feng, Jifeng Guo, Beisha Tang, Zhaohui Zhang, Keqiang Ye, Haiqiang Jiang, Liam Chen, Zhentao Zhang
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
Cerebrotendinous xanthomatosis (CTX), an autosomal recessive disorder characterized by high levels of cholestanol in the blood and accumulation of cholestanol in multiple tissues, especially the brain, often presents in parkinsonism. However, it rema
Externí odkaz:
https://doaj.org/article/955afeea90bf46348fadccd5ba1ffd28
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Lina Pan, Chunrui Li, Lanxia Meng, Ye Tian, Mingyang He, Xin Yuan, Guoxin Zhang, Zhaohui Zhang, Jing Xiong, Guiqin Chen, Zhentao Zhang
Publikováno v:
Brain. 145:3454-3471
The aggregation and prion-like propagation of α-synuclein are involved in the pathogenesis of Parkinson’s disease. However, the underlying mechanisms regulating the assembly and spreading of α-synuclein fibrils remain poorly understood. Tau co-de
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Alzheimer’s and Parkinson’s diseases (AD and PD) are amongst top of the prevalent neurodegenerative disease. One-third of PD patients are diagnosed with dementia, a pre-symptom of AD, but the underlying mechanism is elusive. Amyloid beta (Aβ) an
Externí odkaz:
https://doaj.org/article/e8377e6943bc4f20a5b313a2c8875b70
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience
Alzheimer’s and Parkinson’s diseases (AD and PD) are amongst top of the prevalent neurodegenerative disease. One-third of PD patients are diagnosed with dementia, a pre-symptom of AD, but the underlying mechanism is elusive. Amyloid beta (Aβ) an
Autor:
Zhang, Xingyu1 (AUTHOR), Wang, Jiangyu1 (AUTHOR), Zhang, Zhentao1,2 (AUTHOR) zhentaozhang@whu.edu.cn, Ye, Keqiang3 (AUTHOR) kq.ye@siat.ac.cn
Publikováno v:
Translational Neurodegeneration. 8/6/2024, Vol. 13 Issue 1, p1-17. 17p.
Autor:
Zheng, Liping1 (AUTHOR), Zhou, Cheng2 (AUTHOR), Mao, Chengjie3 (AUTHOR), Xie, Chao1,4,5 (AUTHOR), You, Jia1,4,5 (AUTHOR), Cheng, Wei1,4,5,6 (AUTHOR), Liu, Chunfeng3 (AUTHOR), Huang, Peiyu2 (AUTHOR), Guan, Xiaoujun2 (AUTHOR), Guo, Tao2 (AUTHOR), Wu, Jingjing2 (AUTHOR), Luo, Yajun3 (AUTHOR), Xu, Xiaojun2 (AUTHOR), Zhang, Baorong7 (AUTHOR), Zhang, Minming2 (AUTHOR) zhangminming@zju.edu.cn, Wang, Linbo1,4,5 (AUTHOR) linbowang@fudan.edu.cn, Feng, Jianfeng1,4,5,8,9 (AUTHOR) jffeng@fudan.edu.cn
Publikováno v:
Communications Biology. 8/7/2024, Vol. 7 Issue 1, p1-11. 11p.
Autor:
Venati, Sriya Reddy1 (AUTHOR) sriyareddyvenati@usf.edu, Uversky, Vladimir N.1,2 (AUTHOR) vuversky@usf.edu
Publikováno v:
International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8399. 69p.
Autor:
Guo, Tao1 (AUTHOR), Zhou, Lingyan1 (AUTHOR), Xiong, Min1 (AUTHOR), Xiong, Jing1 (AUTHOR), Huang, Juan2 (AUTHOR), Li, Yiming1 (AUTHOR), Zhang, Guoxin1 (AUTHOR), Chen, Guiqin1 (AUTHOR), Wang, Zhi‐Hao1 (AUTHOR), Xiao, Tingting1 (AUTHOR), Hu, Dan1 (AUTHOR), Bao, Anyu3 (AUTHOR), Zhang, Zhentao1,4 (AUTHOR) zhentaozhang@whu.edu.cn
Publikováno v:
Aging Cell. May2024, Vol. 23 Issue 5, p1-18. 18p.