Zobrazeno 1 - 10
of 69
pro vyhledávání: '"α-ketoglutarate dehydrogenase complex"'
Autor:
Gergő Horváth, Gergely Sváb, Tímea Komlódi, Dora Ravasz, Gergely Kacsó, Judit Doczi, Christos Chinopoulos, Attila Ambrus, László Tretter
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1487 (2022)
α-ketoglutarate dehydrogenase complex (KGDHc), or 2-oxoglutarate dehydrogenase complex (OGDHc) is a rate-limiting enzyme in the tricarboxylic acid cycle, that has been identified in neurodegenerative diseases such as in Alzheimer’s disease. The ai
Externí odkaz:
https://doaj.org/article/e63f5b161a524c698f8f6f43744d2db7
Autor:
Konstantin Plokhikh, Roman Kamyshinsky, Yury Chesnokov, Semen Nesterov, Raif Vasilov, Lev Yaguzhinsky
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 17-18 (2021)
Background: Electron transport chain (ETC) complexes, pyruvate dehydrogenase complex (PDC), and α-ketoglutarate dehydrogenase complex (KGDC) are important elements in mitochondrial metabolism. The localization of the aforementioned protein complexes
Externí odkaz:
https://doaj.org/article/70b6fad27a404ac48f9566b8848e43c2
Autor:
Reithner, Fiona
In dieser Arbeit geht es um die Bedeutung des Metabolismus von Glutamat im Rahmen neuronaler Exzitotoxizität. Unter bestimmten Bedingungen, zum Beispiel bei einem Schlaganfall oder bei neurodegenerativen Erkrankungen, kann es zu einer Akkumulation v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10650::978e749c9ac0ef1e50185714b7a01acc
Autor:
Lichuan Yang, Qingli Shi, Daniel J. Ho, Anatoly A. Starkov, Elizabeth J. Wille, Hui Xu, H.L. Chen, Steven Zhang, Cliona M. Stack, Noel Y. Calingasan, Gary E. Gibson, M. Flint Beal
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 2, Pp 320-330 (2009)
The activity of a key mitochondrial tricarboxylic acid cycle enzyme, α-ketoglutarate dehydrogenase complex (KGDHC), declines in many neurodegenerative diseases. KGDHC consists of three subunits. The dihydrolipoyl succinyl transferase (DLST) componen
Externí odkaz:
https://doaj.org/article/e589e19bf5b940afab0ecdf08e74249c
Autor:
Edward Owusu-Ansah, Christian Garcia, Sergey Sosunov, Zoya Niatsetskaya, Anna Stepanova, Vadim Ten, Alexander Galkin, Belem Yoval-Sánchez, Fariha Ansari, Ilka Wittig
Publikováno v:
The Journal of Biological Chemistry
Impairments in mitochondrial energy metabolism have been implicated in human genetic diseases associated with mitochondrial and nuclear DNA mutations, neurodegenerative and cardiovascular disorders, diabetes, and aging. Alteration in mitochondrial co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bb0f4587b2ffb9835213ba93fb65a1
http://europepmc.org/articles/PMC8503622
http://europepmc.org/articles/PMC8503622
Akademický článek
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Autor:
Roman Kamyshinsky, Konstantin Plokhikh, R. G. Vasilov, Semen V. Nesterov, Lev S. Yaguzhinsky, Yury Chesnokov
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 17-18 (2021)
Background: Electron transport chain (ETC) complexes, pyruvate dehydrogenase complex (PDC), and α-ketoglutarate dehydrogenase complex (KGDC) are important elements in mitochondrial metabolism. The localization of the aforementioned protein complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d24085da99c26cb0c5c6a890bcd5cbb
http://ijbm.org/articles/v11s1/ijbm_2021_11_s1_p15.pdf
http://ijbm.org/articles/v11s1/ijbm_2021_11_s1_p15.pdf
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Anna Maria Porcelli, Michele Vidone, Renaud Vatrinet, Monica De Luise, Giuseppe Gasparre, Giulia Girolimetti, Giulia Leone
Publikováno v:
Cancer & Metabolism
Deregulated metabolism is a well-established hallmark of cancer. At the hub of various metabolic pathways deeply integrated within mitochondrial functions, the α-ketoglutarate dehydrogenase complex represents a major modulator of electron transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4b03ec5ddf98f4ac685a9b33fc5246
https://doi.org/10.1186/s40170-017-0165-0
https://doi.org/10.1186/s40170-017-0165-0
Autor:
Marjorie do Val Ietsugu, Luiz Eduardo Betting, Laís Augusti, Sonia Marta Moriguchi, Lívia Alves Amaral Santos, Talles Bazeia Lima, Matheus Alvarez, Fernando Gomes Romeiro, Giovanni Faria Silva, Letícia de Campos Franzoni, Katia Hiromoto Koga, Carlos Antonio Caramori
Publikováno v:
Neuroimage Clin
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
NeuroImage : Clinical
NeuroImage: Clinical, Vol 19, Iss, Pp 302-310 (2018)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
NeuroImage : Clinical
NeuroImage: Clinical, Vol 19, Iss, Pp 302-310 (2018)
Branched-chain amino acids increase the brain perfusion of patients with hepatic encephalopathy (HE), but the amino acid and the mechanisms involved are still unknown. This study compared brain perfusion and clinical improvement during leucine or iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7ef0f93da643308d41119c79aa2dbd
https://pubmed.ncbi.nlm.nih.gov/33189606
https://pubmed.ncbi.nlm.nih.gov/33189606