Zobrazeno 1 - 10
of 153
pro vyhledávání: '"α-hederin"'
Autor:
Feng Jin, Xiaomin Jiang, Xiaochen Ni, Shilong Yu, Feng Wu, Xinlin Shi, Defang Mao, Haibo Wang, Qingtong Shi, Yanqing Liu, Qin Xu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Lung cancer is the most common oncological disease worldwide, with non-small cell lung cancer accounting for approximately 85% of lung cancer cases. α-Hederin is a monodesmosidic triterpenoid saponin isolated from the leaves of Hedera helix
Externí odkaz:
https://doaj.org/article/a06f4b5a185b4072ad67442ea228b590
Autor:
Xiwu Rao, Ziwen Li, Qinchang Zhang, Yueyang Lai, Jianrong Liu, Liu Li, Haibo Cheng, Weixing Shen, Dongdong Sun
Publikováno v:
Cancer Medicine, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract Background Non‐apoptotic cell death is presently emerging as a potential direction to overcome the apoptosis resistance of cancer cells. In the current study, a natural plant agent α‐hederin (α‐hed) induces caspase‐independent para
Externí odkaz:
https://doaj.org/article/7f04065b5e64421085780e2ef1fa7348
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 50, Iss 8, Pp 745-752 (2023)
Objective To explore the regulative effect of α-Hederin on the proliferation and invasion of NSCLC and investigate its related molecular mechanism. Methods After A549 and HCC-1833 cells were treated with a concentration gradient of α-Hederin for 24
Externí odkaz:
https://doaj.org/article/33590a9a00c64494a1f78c37ec98876e
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116097- (2024)
α-Hederin is a monosaccharide pentacyclic triterpene saponin compound derived from the Chinese herb, Pulsatilla. It has garnered considerable attention for its anti-tumor, anti-inflammatory, and spasmolytic pharmacological activities. Given the risi
Externí odkaz:
https://doaj.org/article/2c1575f4dbe34f459a0569286e76ca6d
Autor:
Zeng Junan, Zhao Guangyu
Publikováno v:
Open Medicine, Vol 18, Iss 1, Pp 203-23 (2023)
Sepsis is one of the most fatal inflammatory diseases with multiple organ failure caused by pathological infection. α-Hederin, a monodesmosidic triterpenoid saponin, has many biological activities including anti-inflammation. This study aimed to inv
Externí odkaz:
https://doaj.org/article/b7f34fca1b7a468cb7dd022dc16ce1ae
Akademický článek
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Akademický článek
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Publikováno v:
Biomedicine & Pharmacotherapy, Vol 150, Iss , Pp 112927- (2022)
Emerging studies showed that α-hederin induced autophagic cell death in different cancers via reactive oxygen species. Nevertheless, α-hederin role in non-small-cell lung cancer (NSCLC) remains unknown. So, the aim of this study was to explain whet
Externí odkaz:
https://doaj.org/article/1b92c39d9a594da89864819282c21a9e
Autor:
Samah M. Elaidy, Mohamed K. El-Kherbetawy, Sally Y. Abed, Abdullah Alattar, Reem Alshaman, Mohamed Ahmed Eladl, Eman Saad Alamri, Aisha Nawaf Al balawi, AbdelNaser Zaid, Amany Y. Elkazzaz, Sozan M. Abdelkhalig, Ziad E. Hamed, Sawsan A. Zaitone
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 405 (2023)
Stromal cell-derived factor-1 (SDF1) and its C-X-C chemokine receptor type 4 receptor (CXCR4) are significant mediators for cancer cells’ proliferation, and we studied their expression in Ehrlich solid tumors (ESTs) grown in mice. α-Hederin is a p
Externí odkaz:
https://doaj.org/article/ca1eaa78fa114e5eb59cc7c69f20f6db
Autor:
Tongqing Chen, Dongdong Sun, Qijuan Wang, Tingting Zhou, Jiani Tan, Changliang Xu, Haibo Cheng, Weixing Shen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
AimsYes-associated protein (YAP), a downstream protein in the Hippo signaling pathway, plays an important role in tumor proliferation, including in hepatocellular carcinoma (HCC). α-hederin, a monodesmosidic triterpenoid saponin isolated from Fructu
Externí odkaz:
https://doaj.org/article/78a560525d6e47b5bf10c4fcd4fa9885