Zobrazeno 1 - 10
of 639
pro vyhledávání: '"α-gal"'
Autor:
Carolina Teles Barretto, Márcia Helena Cassago Nascimento, Bruna Ferro Brun, Tiago Barcelos da Silva, Pedro Augusto Costa Dias, Cassiano Augusto Braga Silva, Maneesh N. Singh, Francis L. Martin, Paulo Roberto Filgueiras, Wanderson Romão, Luciene Cristina Gastalho Campos, Valerio Garrone Barauna
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Fabry disease (FD) is a rare X-linked lysosomal storage disorder marked by alpha-galactosidase-A (α-Gal A) deficiency, caused by pathogenic mutations in the GLA gene, resulting in the accumulation of glycosphingolipids within lys
Externí odkaz:
https://doaj.org/article/9d8acc5dbdd94cfda34b04677ca3a383
Autor:
Neera Chakrapani, Kyra Swiontek, Judith M. Hübschen, Jörg Fischer, Maria Ruiz‐Castell, Francoise Codreanu‐Morel, Farah Hannachi, Martine Morisset, Markus Ollert, Annette Kuehn, Claude P. Muller, Christiane Hilger
Publikováno v:
Clinical and Translational Allergy, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background The α‐Gal syndrome (AGS) is characterized by the presence of specific IgE‐antibodies to the carbohydrate galactose‐α‐1,3‐galactose (α‐Gal). Sensitization to α‐Gal has been associated with tick bites and individua
Externí odkaz:
https://doaj.org/article/94598a661ce94feb8031079258f6a973
Autor:
Uri Galili
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1263 (2024)
A major reason for the failure of the immune system to detect tumor antigens (TAs) is the insufficient uptake, processing, and presentation of TAs by antigen-presenting cells (APCs). The immunogenicity of TAs in the individual patient can be markedly
Externí odkaz:
https://doaj.org/article/8a52f33292ad47f497a7609ec59f7c3b
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
Fabry disease, a lysosomal storage disease, is an uncommon X-linked recessive genetic disorder stemming from abnormalities in the alpha-galactosidase gene (GLA) that codes human alpha-Galactosidase A (α-Gal A). To date, over 800 GLA mutations have b
Externí odkaz:
https://doaj.org/article/54d0a06e5b9743b185c05bff95349b32
Autor:
Miriele Caroline da Silva, Wagner Loyola, Mônica Corrêa Ledur, Alexandre Oba, Emerson Jose Venâncio
Publikováno v:
Semina: Ciências Agrárias, Vol 45, Iss 4 (2024)
The antibodies produced in the first days of vertebrate life and are called natural antibodies (NAb). Other antibodies, produced in response to restricted contact with the antigen, are called specific antibodies (SpAb). To evaluate the production of
Externí odkaz:
https://doaj.org/article/4bd2c53950784f789769b77b40390d75
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
Allergy and its manifestations were first appreciated in the 1870 s. Today, the mechanism by which specific substances elicit allergic reactions remains poorly understood. This is problematic from a healthcare perspective because the prevalence of al
Externí odkaz:
https://doaj.org/article/b24aa1d1e6714bdfac42fbb16a9df9da
Autor:
Ying Wang, Miriam Hils, Andrea Fischer, Florian Wölbing, Tilo Biedermann, Angelika Schnieke, Konrad Fischer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The prevalence of food allergy is rising and is estimated to approach 10%. Red meat allergy is the first known food allergy elicited by immunoglobulin E (IgE) antibodies recognizing a carbohydrate. Due to the loss of function of the alpha−1,3−gal
Externí odkaz:
https://doaj.org/article/f99ab7ca441d497e99dd12b29253047e
Autor:
Marija Perusko, Jeanette Grundström, Maria Eldh, Carl Hamsten, Danijela Apostolovic, Marianne van Hage
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The galactose-α-1,3-galactose (α-Gal) epitope is the cause of a global allergic disease, the α-Gal syndrome (AGS). It is a severe form of allergy to food and products of mammalian origin where IgE against the mammalian carbohydrate, α-Gal, is the
Externí odkaz:
https://doaj.org/article/502bdc9012fa4ae795247120113235cd
Autor:
Julia Szymonik, Sebastian Szopa
Publikováno v:
Quality in Sport, Vol 17 (2024)
Introduction: Alpha-gal syndrome (AGS) arises from tick bites, triggering excessive IgE antibodies to galactose-α-1,3-galactose (α-Gal). Symptoms vary, often appearing post-α-Gal ingestion, ranging from mild to severe, including urticaria, angioed
Externí odkaz:
https://doaj.org/article/b41236188e7d454795ab92e444e58331
Autor:
Mulan Deng, Hongyu Zhou, Shaomei He, Haoheng Qiu, Yanping Wang, April Yuanyi Zhao, Yunping Mu, Fanghong Li, Allan Zijian Zhao
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background Fabry disease (FD) is a progressive multisystemic disease characterized by a lysosomal enzyme deficiency. A lack of α-galactosidase A (α-Gal A) activity results in the progressive systemic accumulation of its substrates, includi
Externí odkaz:
https://doaj.org/article/db59864a565d4f54ad60dc9bf0bd89de