Zobrazeno 1 - 10
of 1 621
pro vyhledávání: '"α smooth muscle actin"'
Autor:
Nilesh Sudhakar Ambhore, Premanand Balraj, Ashish Kumar, Mohammad Irshad Reza, Yogaraj S. Ramakrishnan, Jacob Tesch, Sahil Lohana, Venkatachalem Sathish
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background In asthma, sex-steroids signaling is recognized as a critical regulator of disease pathophysiology. However, the paradoxical role of sex-steroids, especially estrogen, suggests that an upstream mechanism or even independent of est
Externí odkaz:
https://doaj.org/article/1374b887534941a691c4103e49c319ef
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Fibrosis is an abnormal tissue healing process characterized by the excessive accumulation of ECM components, such as COL I and COL III, in response to tissue injury or chronic inflammation. Recent advances in epitranscriptomics have undersc
Externí odkaz:
https://doaj.org/article/a8d1a8b49fa146fba629217570eaa2bb
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 7, Pp 832-840 (2024)
Objective(s): Slit guidance ligand 3 (SLIT3) has been identified as a potential therapeutic regulator against fibroblast activity and fibrillary collagen production in an autocrine manner. However, this research aims to investigate the potential role
Externí odkaz:
https://doaj.org/article/532d63f25b054662b67196e1964d033d
Autor:
Fatemeh Eskandari-Malayeri, Marzieh Rezeai, Tahmineh Narimani, Nafiseh Esmaeil, Mahdieh Azizi
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Fusobacterium nucleatum, (F. nucleatum) as a known factor in inducing oncogenic, invasive, and inflammatory responses, can lead to an increase in the incidence and progression of colorectal cancer (CRC). Cancer-associated fibroblasts (CAF) a
Externí odkaz:
https://doaj.org/article/ef2d5702d4994ac7be5ae293fa34bde1
Autor:
Keiko Seino, Tomoyuki Nakano, Toshiaki Tanaka, Yasukazu Hozumi, Matthew K. Topham, Kaoru Goto, Ken Iseki
Publikováno v:
FEBS Open Bio, Vol 14, Iss 2, Pp 300-308 (2024)
Expression of α‐smooth muscle actin (αSMA) is constitutive in vascular smooth muscle cells, but is induced in nonmuscle cells such as hepatic stellate cells (HSCs). HSCs play important roles in both physiological homeostasis and pathological resp
Externí odkaz:
https://doaj.org/article/3068bee3ba404d47bbc2cb2ea859d866
Publikováno v:
ESC Heart Failure, Vol 11, Iss 1, Pp 492-502 (2024)
Abstract Aims There are few studies on the treatment of heart failure by injecting stem cells into the pericardial cavity. Can the cells injected into the pericardial cavity migrate through the epicardium to the myocardial tissue? Whether there is th
Externí odkaz:
https://doaj.org/article/9f74857bbb864d1090eb35a8aae6caf5
Publikováno v:
Guoji Yanke Zazhi, Vol 23, Iss 9, Pp 1454-1460 (2023)
AIM: To investigate the effect of the intravitreal injection of vascular endothelial growth factor-A165(VEGF-A165)on the scleral remodeling of guinea pigs with form-deprivation myopia(FDM).METHODS: A total of 120 tricolor guinea pigs, aged three week
Externí odkaz:
https://doaj.org/article/07d2679de2ce403da54586bb002531ad
Autor:
Md Rashedunnabi Akanda, Eun-Jung Ahn, Yeong Jin Kim, S M Abdus Salam, Myung-Giun Noh, Tae-Kyu Lee, Sung Sun Kim, Kyung-Hwa Lee, Kyung-Sub Moon
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Breast cancer brain metastasis (BCBM) is a growing therapeutic challenge and clinical concern. Stromal cancer-associated fibroblasts (CAFs) are crucial factors in the modulation of tumorigeneses and metastases. Herein, we investig
Externí odkaz:
https://doaj.org/article/cd731f35159245e59bf32f6c51058b48
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5244 (2024)
We previously found IQ motif containing GTPase activating protein (IQGAP1) to be consistently elevated in lung fibroblasts (LF) isolated from patients with scleroderma (systemic sclerosis, SSc)-associated interstitial lung disease (ILD) and reported
Externí odkaz:
https://doaj.org/article/7afdb2de64aa42ab8e14cace0159914e
Publikováno v:
Medicina, Vol 60, Iss 5, p 816 (2024)
Background and Objectives: This study aims to compare the neuromuscular structure of the vagina in women with posterior vaginal wall prolapse with the neuromuscular structure of the vagina in women without prolapse, to determine the difference, and t
Externí odkaz:
https://doaj.org/article/0248636ba1c14eb4b4569f877e7ff5f9