Zobrazeno 1 - 10
of 132
pro vyhledávání: '"α/β hydrolase fold"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
In recent years, the acyl-Coenzyme A thioester hydrolase family (ACOTs) has received wide attention as a key link in lipid metabolism. This family is a class of enzymes that catalyze the hydrolysis of fatty acyl-Coenzyme A, disrupting the thioester b
Externí odkaz:
https://doaj.org/article/72b57eb3a56e4c06ad954ecd96abd338
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Objective The fungus Metarhizium brunneum produces ergot alkaloids of the lysergic acid amide class, most abundantly lysergic acid α-hydroxyethylamide (LAH). Genes for making ergot alkaloids are clustered in the genomes of producers. Gene c
Externí odkaz:
https://doaj.org/article/ced38754dae94837a05b59392e8eb718
Autor:
Vega Miguel-Ruano, Ivanna Rivera, Jelena Rajkovic, Kamila Knapik, Ana Torrado, José Manuel Otero, Elisa Beneventi, Manuel Becerra, Mercedes Sánchez-Costa, Aurelio Hidalgo, José Berenguer, María-Isabel González-Siso, Jacobo Cruces, María L. Rúa, Juan A. Hermoso
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1214-1232 (2021)
A novel esterase, EstD11, has been discovered in a hot spring metagenomic library. It is a thermophilic and thermostable esterase with an optimum temperature of 60°C. A detailed substrate preference analysis of EstD11 was done using a library of chr
Externí odkaz:
https://doaj.org/article/e0e968e378104a6e9475a7f546816be6
Publikováno v:
FEBS Open Bio, Vol 9, Iss 7, Pp 1337-1343 (2019)
Yeast carboxypeptidase Y (CPY) is a serine protease with broad substrate specificity. Structurally, CPY belongs to the α/β hydrolase fold family and contains characteristic large helices, termed the V‐shape helix, above the active site cavity. Fo
Externí odkaz:
https://doaj.org/article/82972e1659154613823000446753f7a0
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2016 Dec . 113(50), 14318-14323.
Externí odkaz:
https://www.jstor.org/stable/26472836
Autor:
Kyung Rok Kim, Kyung A. Kim, Joon Sung Park, Jun Young Jang, Yuri Choi, Hyung Ho Lee, Dong Chul Lee, Kyung Chan Park, Young Il Yeom, Hyun-Jung Kim, Byung Woo Han
Publikováno v:
Biomolecules, Vol 10, Iss 1, p 90 (2020)
The N-Myc downstream-regulated gene (NDRG) family belongs to the α/β-hydrolase fold and is known to exert various physiologic functions in cell proliferation, differentiation, and hypoxia-induced cancer metabolism. In particular, NDRG3 is closely r
Externí odkaz:
https://doaj.org/article/7d2ea94d8a69402c86ccd496a7756752
Autor:
Helgit Eisner, Lina Riegler-Berket, Carlos Francisco Rodriguez Gamez, Theo Sagmeister, Gabriel Chalhoub, Barbara Darnhofer, P J Jazleena, Ruth Birner-Gruenberger, Tea Pavkov-Keller, Guenter Haemmerle, Gabriele Schoiswohl, Monika Oberer
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13101
Members of the carboxylesterase 2 (Ces2/CES2) family have been studied intensively with respect to their hydrolytic function on (pro)drugs, whereas their physiological role in lipid and energy metabolism has been realized only within the last few yea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8e9363d21426ed7a77426148cc16ca
https://pubmed.ncbi.nlm.nih.gov/36361897
https://pubmed.ncbi.nlm.nih.gov/36361897
Autor:
Gabriela Montero-Moran, Jorge M. Caviglia, Derek McMahon, Alexis Rothenberg, Vidya Subramanian, Zhi Xu, Samuel Lara-Gonzalez, Judith Storch, George M. Carman, Dawn L. Brasaemle
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 4, Pp 709-719 (2010)
Mutations in human CGI-58/ABHD5 cause Chanarin-Dorfman syndrome (CDS), characterized by excessive storage of triacylglycerol in tissues. CGI-58 is an α/β-hydrolase fold enzyme expressed in all vertebrates. The carboxyl terminus includes a highly co
Externí odkaz:
https://doaj.org/article/ace0162c51bc47f6845228a87c2862a3
Autor:
Yves Bourne, Pascale Marchot
Publikováno v:
Molecules, Vol 23, Iss 1, p 35 (2017)
The hydrolytic enzymes acetyl- and butyryl-cholinesterase, the cell adhesion molecules neuroligins, and the hormonogenic macromolecule thyroglobulin are a few of the many members of the α/β hydrolase fold superfamily of proteins. Despite their dist
Externí odkaz:
https://doaj.org/article/d611e304c0ab4cc8a6b02d023a7745e8